Distinguishing between a first episode of multiple sclerosis and acute disseminated encephalomyelitis in children who present with an initial demyelinating event can be a clinical challenge. New brain MRI criteria that aim to differentiate these clinical presentations, and revised McDonald MRI criteria specific for the pediatric population, are both worthy of note.
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Chabas, D., Pelletier, D. Sorting through the pediatric MS spectrum with brain MRI. Nat Rev Neurol 5, 186–188 (2009). https://doi.org/10.1038/nrneurol.2009.35
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DOI: https://doi.org/10.1038/nrneurol.2009.35