In 49 patients with long-standing and active ankylosing spondylitis, anti-TNF treatment did not improve arterial stiffness (as measured by augmentation index and pulse wave velocity) after 6 months or 12 months, despite improvements in inflammation and disease activity. Lipid profiles and other cardiovascular risk factors also remained unchanged.
ORIGINAL RESEARCH PAPER
Mathieu, S. et al. No significant changes in arterial stiffness in patients with ankylosing spondylitis after tumour necrosis factor α blockade treatment for 6 and 12 months. Rheumatology (Oxford) doi:10.1093/rheumatology/kes272
Rights and permissions
About this article
Cite this article
Arterial stiffness unchanged by anti-TNF therapy. Nat Rev Rheumatol 8, 692 (2012). https://doi.org/10.1038/nrrheum.2012.196
Published:
Issue Date:
DOI: https://doi.org/10.1038/nrrheum.2012.196
