Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Comment
  • Published:

A congress on head and neck paragangliomas: advancing clinical care

Nature Reviews Endocrinology (2024)Cite this article

Subjects

The First International Congress on Head and Neck Paragangliomas in 2023 launched a global initiative directed towards improving the management of head and neck paragangliomas (HNPGLs), including prevention, treatment and research. The Congress highlighted a lack of international evidence-based consensuses and guidelines for HNPGLs. The Congress will now convene triennially to foster personalized medicine and research to advance patient care.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Pacak, K., Eisenhofer, G. & Tischler, A. S. Phaeochromocytoma-advances through science, collaboration and spreading the word. Nat. Rev. Endocrinol. 16, 621–622 (2020).

    Article  PubMed  Google Scholar 

  2. Tooker, E. L. et al. The natural history of observed SDHx-related head and neck paragangliomas using three-dimensional volumetric tumor analysis. Otol. Neurotol. 44, 931–940 (2023).

    Article  PubMed  Google Scholar 

  3. Jansen, T. T. G., Timmers, H. J. L. M., Marres, H. A. M. & Kunst, H. P. M. Feasibility of a wait-and-scan period as initial management strategy for head and neck paraganglioma. Head Neck 39, 2088–2094 (2017).

    Article  PubMed  Google Scholar 

  4. Richter, S. et al. Head/neck paragangliomas: focus on tumor location, mutational status and plasma methoxytyramine. Endocr. Relat. Cancer 29, 213–224 (2022).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  5. McCrary, H. C. et al. Characterization of malignant head and neck paragangliomas at a single institution across multiple decades. JAMA Otolaryngol. Head Neck Surg. 145, 641–646 (2019).

    Article  PubMed  PubMed Central  Google Scholar 

  6. Taïeb, D. et al. Clinical consensus guideline on the management of phaeochromocytoma and paraganglioma in patients harbouring germline SDHD pathogenic variants. Lancet Diabetes Endocrinol. 11, 345–361 (2023).

    Article  PubMed  Google Scholar 

  7. Prasad, S. C. et al. The role of wait-and-scan and the efficacy of radiotherapy in the treatment of temporal bone paragangliomas. Otol. Neurotol. 35, 922–931 (2014).

    Article  PubMed  Google Scholar 

  8. Lloyd, S., Obholzer, R. & Tysome, J. BSBS Consensus Group. British Skull Base Society clinical consensus document on management of head and neck paragangliomas. Otolaryngol. Head Neck Surg. 163, 400–409 (2020).

    Article  PubMed  Google Scholar 

  9. Sanna, M., Piazza, P., Shin, S.-H., Flanagan, S. & Mancini, F. Microsurgery of Skull Base Paraganglioma (Thieme, 2013).

  10. Pamporaki, C. et al. Prediction of metastatic pheochromocytoma and paraganglioma: a machine learning modelling study using data from a cross-sectional cohort. Lancet Digit. Health 5, e551–e559 (2023).

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

R.M.-C. acknowledges the support of Head and Neck Paraganglioma Research Grants AIRC IG 16932 and AIRC IG 24501, supported by Fondazione AIRC per la Ricerca sul Cancro, viale Isonzo 25, 20135 Milano, Italy.

Author information

Authors and Affiliations

  1. Otology and Skull Base Unit, Gruppo Otologico, Piacenza, Italy

    Mario Sanna

  2. Section on Medical Neuroendocrinology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA

    Karel Pacak

  3. Department of Nuclear Medicine, Aix-Marseille University, La Timone University Hospital, Marseille, France

    David Taїeb

  4. Center for Advanced Studies and Technology, G. d’Annunzio University, Chieti, Italy

    Renato Mariani-Costantini

Authors
  1. Mario Sanna
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Karel Pacak
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. David Taїeb
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Renato Mariani-Costantini
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Karel Pacak.

Ethics declarations

Competing interests

The authors declare no competing interests.

Additional information

Related links

First International Congress, 2023 Update on the Management of Head and Neck Paragangliomas: https://paragangliomas.com

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Sanna, M., Pacak, K., Taїeb, D. et al. A congress on head and neck paragangliomas: advancing clinical care. Nat Rev Endocrinol (2024). https://doi.org/10.1038/s41574-024-00987-9

Download citation

  • Published:

  • DOI: https://doi.org/10.1038/s41574-024-00987-9

Search

Advanced search

Quick links

Nature Briefing: Cancer

Sign up for the Nature Briefing: Cancer newsletter — what matters in cancer research, free to your inbox weekly.

Get what matters in cancer research, free to your inbox weekly. Sign up for Nature Briefing: Cancer