Use of a proteomics approach has demonstrated that changes in protein expression association with Alzheimer disease are not always reflected in changes in RNA levels, highlighting the importance of directly studying proteomic changes to a full understanding of Alzheimer disease pathogenesis.
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Perluigi, M., Barone, E. Aberrant protein networks in Alzheimer disease. Nat Rev Neurol 18, 255–256 (2022). https://doi.org/10.1038/s41582-022-00648-3
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DOI: https://doi.org/10.1038/s41582-022-00648-3
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