Bladder cancer progression to microscopically distinct variants such as sarcomatoid, small cell, micropapillary and plasmacytoid is associated with more aggressive clinical behaviour than conventional carcinoma. Advances in molecular profiling led to the identification of molecular subtypes of bladder cancer and provided insights into disease progression to aggressive variants.
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Czerniak, B. Bladder cancer variants — one disease with many faces. Nat Rev Urol (2024). https://doi.org/10.1038/s41585-024-00886-8
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DOI: https://doi.org/10.1038/s41585-024-00886-8
