Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Thrombocytopathia therapies

Stopping the bleed when platelets don’t stick

Nature Cardiovascular Research volume 3, pages 100–101 (2024)Cite this article

Subjects

Defects in platelet adhesion at sites of injury can lead to excessive bleeding. A study by Gandhi et al. investigates a new bispecific antibody as a possible therapy to prevent bleeding in patients with inherited defects in platelet adhesion.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Orsini, S. et al. Haematologica 102, 1192–1203 (2017).

    Article  PubMed  PubMed Central  Google Scholar 

  2. Fiore, M. et al. Br. J. Haematol. 181, 173–182 (2018).

    Article  CAS  PubMed  Google Scholar 

  3. Siddiq, S. et al. Haemophilia. 17, e858–e869 (2011).

    CAS  PubMed  Google Scholar 

  4. Lisman, T. et al. Blood 103, 1720–1727 (2004).

    Article  CAS  PubMed  Google Scholar 

  5. Poon, M. C. Thromb. Haemost. 121, 332–340 (2021).

    Article  PubMed  Google Scholar 

  6. Friend, B. D. et al. J. Pediatr. Hematol. Oncol. 42, e521–e526 (2020).

    Article  PubMed  Google Scholar 

  7. Palma-Barqueros, V. et al. Haemophilia 28 (S1), Abstract SP022 (2022).

  8. Gandhi, P. et al. Nat. Cardiovas. Res. https://doi.org/10.1038/s44161-023-00418-4 (2024).

    Article  Google Scholar 

  9. Washington, A. V. et al. Blood 104, 1042–1047 (2004).

    Article  CAS  PubMed  Google Scholar 

  10. Morrissey, J. H. et al. Blood 81, 734–744 (1993).

    Article  CAS  PubMed  Google Scholar 

  11. Andiç, N. et al. Blood Coagul. Fibrinolysis 32, 349–351 (2021).

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Hematology, Department of Medicine, Duke University, Durham, NC, USA

    Ammon M. Fager

  2. Division of Hematology/Oncology, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA

    Dougald M. Monroe

Authors
  1. Ammon M. Fager
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Dougald M. Monroe
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Dougald M. Monroe.

Ethics declarations

Competing interests

The authors report no competing interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Fager, A.M., Monroe, D.M. Stopping the bleed when platelets don’t stick. Nat Cardiovasc Res 3, 100–101 (2024). https://doi.org/10.1038/s44161-024-00421-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/s44161-024-00421-3

Search

Advanced search

Quick links

Nature Briefing: Translational Research

Sign up for the Nature Briefing: Translational Research newsletter — top stories in biotechnology, drug discovery and pharma.

Get what matters in translational research, free to your inbox weekly. Sign up for Nature Briefing: Translational Research