By dissecting the cell composition and function of arterial grafts derived from the internal thoracic, radial and right gastroepiploic arteries, we identified factors that might promote patency rates of arterial grafts, including combating lipid deposition, disturbances in wall shear stress, smooth muscle cell proliferation, fibrosis and spasm.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 digital issues and online access to articles
$119.00 per year
only $9.92 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Gaudino, M. et al. The choice of conduits in coronary artery bypass surgery. J. Am. Coll. Cardiol. 66, 1729–1737 (2015). A review article that presents evidence for the use of different conduits in coronary artery bypass surgery and proposes an evidence-based algorithm for the choice of the second conduit during bypass operations.
Yi, G., Shine, B., Rehman, S. M., Altman, D. G. & Taggart, D. P. Effect of bilateral internal mammary artery grafts on long-term survival: a meta-analysis approach. Circulation 130, 539–545 (2014). This paper reports the long-term survival benefit of internal mammary artery grafts.
Tranbaugh, R. F. et al. Radial artery conduits improve long-term survival after coronary artery bypass grafting. Ann. Thorac. Surg. 90, 1165–1172 (2010). This paper reports the advantage of the radial artery compared with the saphenous vein.
Gaudino, M. et al. Mechanisms, consequences, and prevention of coronary graft failure. Circulation 136, 1749–1764 (2017). A review article demonstrating that intrinsic morphological and functional features of the bypass conduits affect graft failure.
Additional information
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This is a summary of: Hu, Z. et al. Strategies for arterial graft optimization at the single-cell level. Nat. Cardiovasc. Res. https://doi.org/10.1038/s44161-024-00464-6 (2024).
Rights and permissions
About this article
Cite this article
Directions for promoting patency of arterial grafts. Nat Cardiovasc Res 3, 498–499 (2024). https://doi.org/10.1038/s44161-024-00466-4
Published:
Issue Date:
DOI: https://doi.org/10.1038/s44161-024-00466-4
