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Smart food packaging commercialization

Smart food packaging technologies can actualize real-time, in situ food quality monitoring, increasing food safety and decreasing food waste. Here, we detail challenges that hinder the commercialization of such smart packaging systems and identify opportunities to facilitate their translation from prototype to product.

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Fig. 1: Advances in real-time, in situ smart food monitoring developed by the Sentinel Wraps Group.

References

  1. Afsana, K., Jolly, S. P. & Akhter, F. in Handbook of Global Health (eds Haring, R. et al.) https://doi.org/10.1007/978-3-030-05325-3_93-2 (Springer, 2022).

  2. Khan, S. et al. Material breakthroughs in smart food monitoring: intelligent packaging and on-site testing technologies for spoilage and contamination detection. Adv. Mater. 36, 2300875 (2023).

    Article  Google Scholar 

  3. Prasad, A. et al. Advancing in situ food monitoring through a smart Lab-in-a-Package system demonstrated by the detection of Salmonella in whole chicken. Adv. Mater. 35, 2302641 (2023).

    Article  Google Scholar 

  4. Li, J. et al. A simple colorimetric Au-on-Au tip sensor with a new functional nucleic acid probe for food-borne pathogen Salmonella typhimurium. Angew. Chem. 135, e202300828 (2023).

    Article  Google Scholar 

  5. Hogan, S. & Kerry, J. Smart packaging of meat and poultry products. Smart packaging technologies for fast moving consumer goods (eds Kerry, J. & Butler, P.) 33–59 (Wiley, 2008).

  6. Yousefi, H., Ali, M. M., Su, H.-M., Filipe, C. D. M. & Didar, T. F. Sentinel wraps: real-time monitoring of food contamination by printing DNAzyme probes on food packaging. ACS Nano 12, 3287–3294 (2018).

    Article  Google Scholar 

  7. Ghosh, P. R., Fawcett, D., Sharma, S. B. & Poinern, G. E. J. Progress towards sustainable utilisation and management of food wastes in the global economy. Int. J. Food Sci. 2016, 3563478 (2016).

    Article  Google Scholar 

  8. Mustafa, F. & Andreescu, S. Nanotechnology-based approaches for food sensing and packaging applications. RSC Adv. 10, 19309–19336 (2020).

    Article  Google Scholar 

  9. Yousefi, H. et al. LISzyme biosensors: DNAzymes embedded in an anti-biofouling platform for hands-free real-time detection of bacterial contamination in milk. ACS Nano 16, 29–37 (2021).

    Article  Google Scholar 

  10. Tian, L. et al. Self-assembling nanofibrous bacteriophage microgels as sprayable antimicrobials targeting multidrug-resistant bacteria. Nat. Commun. 13, 7158 (2022).

    Article  Google Scholar 

  11. Tian, L. et al. High-throughput fabrication of antimicrobial phage microgels and example applications in food decontamination. Nat. Protoc. https://doi.org/10.1038/s41596-024-00964-6 (2024).

    Article  Google Scholar 

  12. Lacombe, A., Quintela, I. A., Liao, Y.-T. & Wu, V. C. Shiga toxin-producing Escherichia coli outbreaks in California’s leafy greens production continuum. Front. Food Sci. Technol. 2, 1068690 (2022).

    Article  Google Scholar 

Download references

Acknowledgements

S.K. is a recipient of a Vanier Canada Graduate Scholarship and Banting Postdoctoral Fellowship from the Natural Sciences and Engineering Research Council. The Sentinel Wraps Group has been supported by NSERC Discovery Grant and Toyota Tsusho Canada Incorporated grants awarded to T.F.D. Additionally, T.F.D. is a Tier II Canada Research Chair in Nanobiomaterials.

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Authors and Affiliations

Authors

Contributions

T.F.D. has founded and led the Sentinel Wraps consortium. S.K. prepared the initial manuscript and subsequent revisions. Z.H. offered guidance and revised the text. C.D.M.F., Y.L. and T.F.D. supervised this work throughout its generation.

Corresponding authors

Correspondence to Yingfu Li, Carlos D. M. Filipe or Tohid F. Didar.

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Competing interests

T.F.D. founded the Sentinel Wraps Group with support from core faculty members Y.L. and C.D.M.F., a consortium that seeks to actualize in-package food monitoring. We have developed several patented smart food technologies that are positioned for rapid real-world translation. Translational efforts are supported by Toyota Tsusho Canada Incorporated (TTCI), who have a global network of partners seeking to employ our systems. Key industry partners continue to support commercial scale-up assessments and initiatives.

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Khan, S., Hosseinidoust, Z., Li, Y. et al. Smart food packaging commercialization. Nat Rev Bioeng (2024). https://doi.org/10.1038/s44222-024-00190-5

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