Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain
the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in
Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles
and JavaScript.
This issue features articles on artificial intelligence, MRONJ, and occlusion.
Cover image: Plaque-forming bacteria. Coloured scanning electron micrograph (SEM) of plaque-forming bacteria. Plaque consists of a film of bacteria embedded in a glycoprotein matrix. The matrix is formed from bacterial secretions and saliva. Plaque is the main cause of tooth decay. The bacteria feed on sugars in food, producing acid as a waste product. This acid corrodes the teeth’s enamel coating, resulting in dental caries. A build-up of dental plaque can also lead to inflamed and infected gums. Severe gum disease can lead to teeth falling out. Magnification: x3000 when printed at 10 cm across.