Welcome to The EMBO Journal


  • New initiatives for 2009

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  • Have You Seen…?

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    • When separation means death: killing through the mitochondria, but starting from the endoplasmic reticulum

      Proapoptotic proteins of the BCL-2 family also exert housekeeping functions at the ER. An intriguing study in this issue of The EMBO Journal finds they can activate the mitochondrial apoptosis pathway even when restricted to the ER, overcoming the spatial restriction of cellular components by employing an unconventional signalling cascade.

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    • ncRNA transcription makes its mark

      Transcription of an overlapping non-coding RNA is a recently recognized strategy for regulating expression of a given target gene. A study in this issue of The EMBO Journal shows how the act of ncRNA transcription itself, rather than the product, can mediate such regulation, through the deposition of histone marks by elongating RNA polymerases.

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  • AOP Highlights

    • Advance online publication
    • 18 June 2009
    • Insights into complement convertase formation based on the structure of the factor B-cobra venom factor complex

      Piet Gros' lab reports here the first crystal structure of the pro-convertase/cobra venom factor complex. By analogy, this reveals crucial insight into pro-convertase assembly and thereby extends our molecular understanding of complement system activation.

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  • Web Focus Collections

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    • Quality control in an unreliable world

      This collection of eight review articles highlights different aspects of cellular quality control and their potential relevance for human diseases.

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    • Let's go to the movies

      Recently published Reviews on imaging of biological membranes, the dynamics of protein structure, gene expression, cell polarity and cell migration, together with a selection of movies from our archive linked to the article in which they originally appeared.

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  • Other Publications

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