Table of Contents : The EMBO Journal

Volume 27, Number 1
09 January 2008

pp 1-301

Chromosomen 323-3 and 323-6 during wintertime - Welded from iron in 2006, these sculptures are about 12 feet high. The artist, Martina Lauinger, has been interested in genetic themes for several years; to find out about her other work and exhibitions, visit www.lauinger.ch

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EMBO Members Review
Top of page
- MHC class II molecules on the move for successful antigen presentation FREE
  Nuno Rocha and Jacques Neefjes
  The EMBO Journal (2008), 27, - 1 - 5, doi:10.1038/sj.emboj.7601945
  Published online: 29 November 2007
  Subject Categories:
  - Membranes and Transport | Immunology
Articles
Top of page
- A versatile interaction platform on the Mex67–Mtr2 receptor creates an overlap between mRNA and ribosome export FREE
  Wei Yao, Malik Lutzmann and Ed Hurt
  The EMBO Journal (2008), 27, - 6 - 16, doi:10.1038/sj.emboj.7601947
  - Abstract - A versatile interaction platform on the Mex67-Mtr2 receptor creates an overlap between mRNA and ribosome export
  - Full text
  - PDF (406 KB) - A versatile interaction platform on the Mex67-Mtr2 receptor creates an overlap between mRNA and ribosome export
  - Supplementary information
  Published online: 29 November 2007
  Subject Categories:
  - Membranes and Transport | Proteins
- Parallel topology of genetically fused EmrE homodimers FREE
  Sonia Steiner-Mordoch, Misha Soskine, Dalia Solomon, Dvir Rotem, Ayala Gold, Michal Yechieli, Yoav Adam and Shimon Schuldiner
  The EMBO Journal (2008), 27, - 17 - 26, doi:10.1038/sj.emboj.7601951
  - Abstract - Parallel topology of genetically fused EmrE homodimers
  - Full text
  - PDF (612 KB) - Parallel topology of genetically fused EmrE homodimers
  Published online: 06 December 2007
  Subject Categories:
  - Membranes and Transport | Proteins
- Real-time detection reveals that effectors couple dynamin's GTP-dependent conformational changes to the membrane FREE
  Rajesh Ramachandran and Sandra L Schmid
  The EMBO Journal (2008), 27, - 27 - 37, doi:10.1038/sj.emboj.7601961
  - Abstract - Real-time detection reveals that effectors couple dynamin's GTP-dependent conformational changes to the membrane
  - Full text
  - PDF (330 KB) - Real-time detection reveals that effectors couple dynamin's GTP-dependent conformational changes to the membrane
  - Supplementary information
  Published online: 13 December 2007
  Subject Categories:
  - Membranes and Transport | Proteins
- Spatial recruitment and activation of the Fes kinase by ezrin promotes HGF-induced cell scattering FREE
  Alexandra Naba, Céline Reverdy, Daniel Louvard and Monique Arpin
  The EMBO Journal (2008), 27, - 38 - 50, doi:10.1038/sj.emboj.7601943
  - Abstract - Spatial recruitment and activation of the Fes kinase by ezrin promotes HGF-induced cell scattering
  - Full text
  - PDF (591 KB) - Spatial recruitment and activation of the Fes kinase by ezrin promotes HGF-induced cell scattering
  - Supplementary information
  Published online: 29 November 2007
  Subject Category:
  - Cell and Tissue Architecture
- Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA EMBO Open
  Lars Hagen, Bodil Kavli, Mirta ML Sousa, Kathrin Torseth, Nina B Liabakk, Ottar Sundheim, Javier Pea-Diaz, Marit Otterlei, Ole Hørning, Ole N Jensen, Hans E Krokan and Geir Slupphaug
  The EMBO Journal (2008), 27, - 51 - 61, doi:10.1038/sj.emboj.7601958
  - Abstract - Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA
  - Full text
  - PDF (592 KB) - Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA
  Published online: 13 December 2007
  Subject Categories:
  - Cell Cycle | Genome Stability and Dynamics
- Intermediate-affinity LFA-1 binds -actinin-1 to control migration at the leading edge of the T cell EMBO Open
  Paula Stanley, Andrew Smith, Alison McDowall, Alastair Nicol, Daniel Zicha and Nancy Hogg
  The EMBO Journal (2008), 27, - 62 - 75, doi:10.1038/sj.emboj.7601959
  - Abstract - Intermediate-affinity LFA-1 binds [alpha]-actinin-1 to control migration at the leading edge of the T cell
  - Full text
  - PDF (641 KB) - Intermediate-affinity LFA-1 binds [alpha]-actinin-1 to control migration at the leading edge of the T cell
  - Supplementary information
  Published online: 13 December 2007
  Subject Categories:
  - Cell and Tissue Architecture | Immunology
- JNK phosphorylates synaptotagmin-4 and enhances Ca²⁺-evoked release FREE
  Yasunori Mori, Maiko Higuchi, Yusuke Hirabayashi, Mitsunori Fukuda and Yukiko Gotoh
  The EMBO Journal (2008), 27, - 76 - 87, doi:10.1038/sj.emboj.7601935
  - Abstract - JNK phosphorylates synaptotagmin-4 and enhances Ca: 2+: -evoked release
  - Full text
  - PDF (581 KB) - JNK phosphorylates synaptotagmin-4 and enhances Ca: 2+: -evoked release
  - Supplementary information
  Published online: 29 November 2007
  Subject Categories:
  - Membranes and Transport | Signal Transduction
- 14-3-3 Proteins recognize a histone code at histone H3 and are required for transcriptional activation FREE
  Stefan Winter, Elisabeth Simboeck, Wolfgang Fischle, Gordin Zupkovitz, Ilse Dohnal, Karl Mechtler, Gustav Ammerer and Christian Seiser
  The EMBO Journal (2008), 27, - 88 - 99, doi:10.1038/sj.emboj.7601954
  - Abstract - 14-3-3 Proteins recognize a histone code at histone H3 and are required for transcriptional activation
  - Full text
  - PDF (454 KB) - 14-3-3 Proteins recognize a histone code at histone H3 and are required for transcriptional activation
  - Supplementary information
  Published online: 06 December 2007
  Subject Category:
  - Chromatin and Transcription
- RSC regulates nucleosome positioning at Pol II genes and density at Pol III genes FREE
  Timothy J Parnell, Jason T Huff and Bradley R Cairns
  The EMBO Journal (2008), 27, - 100 - 110, doi:10.1038/sj.emboj.7601946
  - Abstract - RSC regulates nucleosome positioning at Pol II genes and density at Pol III genes
  - Full text
  - PDF (298 KB) - RSC regulates nucleosome positioning at Pol II genes and density at Pol III genes
  - Supplementary information
  Published online: 06 December 2007
  Subject Category:
  - Chromatin and Transcription
- Cell-cycle regulation of cohesin stability along fission yeast chromosomes FREE
  Pascal Bernard, Christine Katrin Schmidt, Sabine Vaur, Sonia Dheur, Julie Drogat, Sylvie Genier, Karl Ekwall, Frank Uhlmann and Jean-Paul Javerzat
  The EMBO Journal (2008), 27, - 111 - 121, doi:10.1038/sj.emboj.7601955
  - Abstract - Cell-cycle regulation of cohesin stability along fission yeast chromosomes
  - Full text
  - PDF (329 KB) - Cell-cycle regulation of cohesin stability along fission yeast chromosomes
  - Supplementary information
  Published online: 13 December 2007
  Subject Categories:
  - Chromatin and Transcription | Cell Cycle
- Intrasplicing coordinates alternative first exons with alternative splicing in the protein 4.1R gene FREE
  Marilyn K Parra, Jeff S Tan, Narla Mohandas and John G Conboy
  The EMBO Journal (2008), 27, - 122 - 131, doi:10.1038/sj.emboj.7601957
  - Abstract - Intrasplicing coordinates alternative first exons with alternative splicing in the protein 4.1R gene
  - Full text
  - PDF (433 KB) - Intrasplicing coordinates alternative first exons with alternative splicing in the protein 4.1R gene
  Published online: 13 December 2007
  Subject Category:
  - RNA
- Cdc2p controls the forkhead transcription factor Fkh2p by phosphorylation during sexual differentiation in fission yeast FREE
  Midori Shimada, Chisato Yamada-Namikawa, Yuko Murakami-Tonami, Takashi Yoshida, Makoto Nakanishi, Takeshi Urano and Hiroshi Murakami
  The EMBO Journal (2008), 27, - 132 - 142, doi:10.1038/sj.emboj.7601949
  - Abstract - Cdc2p controls the forkhead transcription factor Fkh2p by phosphorylation during sexual differentiation in fission yeast
  - Full text
  - PDF (301 KB) - Cdc2p controls the forkhead transcription factor Fkh2p by phosphorylation during sexual differentiation in fission yeast
  - Supplementary information
  Published online: 06 December 2007
  Subject Category:
  - Cell Cycle
- p166, a link between the trypanosome mitochondrial DNA and flagellum, mediates genome segregation FREE
  Zhixing Zhao, Megan E Lindsay, Arnab Roy Chowdhury, Derrick R Robinson and Paul T Englund
  The EMBO Journal (2008), 27, - 143 - 154, doi:10.1038/sj.emboj.7601956
  - Abstract - p166, a link between the trypanosome mitochondrial DNA and flagellum, mediates genome segregation
  - Full text
  - PDF (562 KB) - p166, a link between the trypanosome mitochondrial DNA and flagellum, mediates genome segregation
  - Supplementary information
  Published online: 06 December 2007
  Subject Category:
  - Genome Stability and Dynamics
- Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step FREE
  Vincent Mocquet, Jean Philippe Lainé, Thilo Riedl, Zhou Yajin, Marietta Y Lee and Jean Marc Egly
  The EMBO Journal (2008), 27, - 155 - 167, doi:10.1038/sj.emboj.7601948
  - Abstract - Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step
  - Full text
  - PDF (543 KB) - Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step
  - Supplementary information
  Published online: 13 December 2007
  Subject Category:
  - Genome Stability and Dynamics
- Two distinct mechanisms of silencing by the KvDMR1 imprinting control region FREE
  Jong-Yeon Shin, Galina V Fitzpatrick and Michael J Higgins
  The EMBO Journal (2008), 27, - 168 - 178, doi:10.1038/sj.emboj.7601960
  - Abstract - Two distinct mechanisms of silencing by the KvDMR1 imprinting control region
  - Full text
  - PDF (538 KB) - Two distinct mechanisms of silencing by the KvDMR1 imprinting control region
  - Supplementary information
  Published online: 13 December 2007
  Subject Categories:
  - Chromatin and Transcription | Development
- Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis FREE
  Dirk Heitzmann, Renaud Derand, Stefan Jungbauer, Sascha Bandulik, Christina Sterner, Frank Schweda, Abeer El Wakil, Enzo Lalli, Nicolas Guy, Raymond Mengual, Markus Reichold, Ines Tegtmeier, Saïd Bendahhou, Celso E Gomez-Sanchez, M Isabel Aller, William Wisden, Achim Weber, Florian Lesage, Richard Warth and Jacques Barhanin
  The EMBO Journal (2008), 27, - 179 - 187, doi:10.1038/sj.emboj.7601934
  - Abstract - Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis
  - Full text
  - PDF (437 KB) - Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis
  Published online: 22 November 2007
  Subject Categories:
  - Membranes and Transport | Cellular Metabolism
- Neural recognition molecules CHL1 and NB-3 regulate apical dendrite orientation in the neocortex via PTP FREE
  Haihong Ye, Yen Ling Jessie Tan, Sathivel Ponniah, Yasuo Takeda, Shi-Qiang Wang, Melitta Schachner, Kazutada Watanabe, Catherine J Pallen and Zhi-Cheng Xiao
  The EMBO Journal (2008), 27, - 188 - 200, doi:10.1038/sj.emboj.7601939
  - Abstract - Neural recognition molecules CHL1 and NB-3 regulate apical dendrite orientation in the neocortex via PTP[alpha]
  - Full text
  - PDF (874 KB) - Neural recognition molecules CHL1 and NB-3 regulate apical dendrite orientation in the neocortex via PTP[alpha]
  - Supplementary information
  Published online: 29 November 2007
  Subject Category:
  - Neuroscience
- Hsp90-mediated cytosolic refolding of exogenous proteins internalized by dendritic cells EMBO Open
  Alessandra Giodini and Peter Cresswell
  The EMBO Journal (2008), 27, - 201 - 211, doi:10.1038/sj.emboj.7601941
  - Abstract - Hsp90-mediated cytosolic refolding of exogenous proteins internalized by dendritic cells
  - Full text
  - PDF (286 KB) - Hsp90-mediated cytosolic refolding of exogenous proteins internalized by dendritic cells
  - Supplementary information
  Published online: 29 November 2007
  Subject Categories:
  - Proteins | Immunology
- Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance FREE
  Tobias A Beyer, Weihua Xu, Daniel Teupser, Ulrich auf dem Keller, Philippe Bugnon, Eberhard Hildt, Joachim Thiery, Yuet Wai Kan and Sabine Werner
  The EMBO Journal (2008), 27, - 212 - 223, doi:10.1038/sj.emboj.7601950
  - Abstract - Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance
  - Full text
  - PDF (343 KB) - Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance
  - Supplementary information
  Published online: 06 December 2007
  Subject Categories:
  - Signal Transduction | Molecular Biology of Disease
- Lipids revert inert A amyloid fibrils to neurotoxic protofibrils that affect learning in mice EMBO Open
  Ivo Cristiano Martins, Inna Kuperstein, Hannah Wilkinson, Elke Maes, Mieke Vanbrabant, Wim Jonckheere, Patrick Van Gelder, Dieter Hartmann, Rudi D'Hooge, Bart De Strooper, Joost Schymkowitz and Frederic Rousseau
  The EMBO Journal (2008), 27, - 224 - 233, doi:10.1038/sj.emboj.7601953
  - Abstract - Lipids revert inert A[beta] amyloid fibrils to neurotoxic protofibrils that affect learning in mice
  - Full text
  - PDF (480 KB) - Lipids revert inert A[beta] amyloid fibrils to neurotoxic protofibrils that affect learning in mice
  - Supplementary information
  Published online: 06 December 2007
  Subject Categories:
  - Molecular Biology of Disease | Structural Biology
- Structure-guided identification of a new catalytic motif of oligosaccharyltransferase FREE
  Mayumi Igura, Nobuo Maita, Jun Kamishikiryo, Masaki Yamada, Takayuki Obita, Katsumi Maenaka and Daisuke Kohda
  The EMBO Journal (2008), 27, - 234 - 243, doi:10.1038/sj.emboj.7601940
  - Abstract - Structure-guided identification of a new catalytic motif of oligosaccharyltransferase
  - Full text
  - PDF (448 KB) - Structure-guided identification of a new catalytic motif of oligosaccharyltransferase
  - Supplementary information
  Published online: 29 November 2007
  Subject Categories:
  - Proteins | Structural Biology
- The post-rigor structure of myosin VI and implications for the recovery stroke FREE
  Julie Ménétrey, Paola Llinas, Jérome Cicolari, Gaëlle Squires, Xiaoyan Liu, Anna Li, H Lee Sweeney and Anne Houdusse
  The EMBO Journal (2008), 27, - 244 - 252, doi:10.1038/sj.emboj.7601937
  - Abstract - The post-rigor structure of myosin VI and implications for the recovery stroke
  - Full text
  - PDF (623 KB) - The post-rigor structure of myosin VI and implications for the recovery stroke
  - Supplementary information
  Published online: 29 November 2007
  Subject Category:
  - Structural Biology
- Molecular basis of the C-terminal tail-to-tail assembly of the sarcomeric filament protein myomesin FREE
  Nikos Pinotsis, Stephan Lange, Jean-Claude Perriard, Dmitri I Svergun and Matthias Wilmanns
  The EMBO Journal (2008), 27, - 253 - 264, doi:10.1038/sj.emboj.7601944
  - Abstract - Molecular basis of the C-terminal tail-to-tail assembly of the sarcomeric filament protein myomesin
  - Full text
  - PDF (526 KB) - Molecular basis of the C-terminal tail-to-tail assembly of the sarcomeric filament protein myomesin
  Published online: 06 December 2007
  Subject Categories:
  - Cell and Tissue Architecture | Structural Biology
- Structure and functional analysis of the IGF-II/IGF2R interaction FREE
  James Brown, Carlie Delaine, Oliver J Zaccheo, Christian Siebold, Robert J Gilbert, Gijs van Boxel, Adam Denley, John C Wallace, A Bassim Hassan, Briony E Forbes and E Yvonne Jones
  The EMBO Journal (2008), 27, - 265 - 276, doi:10.1038/sj.emboj.7601938
  - Abstract - Structure and functional analysis of the IGF-II/IGF2R interaction
  - Full text
  - PDF (736 KB) - Structure and functional analysis of the IGF-II/IGF2R interaction
  - Supplementary information
  Published online: 29 November 2007
  Subject Categories:
  - Signal Transduction | Structural Biology
- Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition EMBO Open
  Gregg V Crichlow, Hongwen Zhou, Hsin-hao Hsiao, Kendra B Frederick, Maxime Debrosse, Yuande Yang, Ewa J Folta-Stogniew, Hye-Jung Chung, Chengpeng Fan, Enrique M De La Cruz, David Levens, Elias Lolis and Demetrios Braddock
  The EMBO Journal (2008), 27, - 277 - 289, doi:10.1038/sj.emboj.7601936
  - Abstract - Dimerization of FIR upon FUSE DNA binding suggests a mechanism of : c-myc: inhibition
  - Full text
  - PDF (640 KB) - Dimerization of FIR upon FUSE DNA binding suggests a mechanism of : c-myc: inhibition
  - Supplementary information
  Published online: 06 December 2007
  Subject Categories:
  - Chromatin and Transcription | Structural Biology
- Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ EMBO Open
  Yi Li, Dimitri Y Chirgadze, Victor M Bolanos-Garcia, Bancinyane L Sibanda, Owen R Davies, Peter Ahnesorg, Stephen P Jackson and Tom L Blundell
  The EMBO Journal (2008), 27, - 290 - 300, doi:10.1038/sj.emboj.7601942
  - Abstract - Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ
  - Full text
  - PDF (515 KB) - Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ
  - Supplementary information
  Published online: 29 November 2007
  Subject Categories:
  - Cell Cycle | Structural Biology
Retraction
Top of page
- TRiC/CCT cooperates with different upstream chaperones in the folding of distinct protein classes FREE
  Katja Siegers, Bettina Bölter, Juliane P Schwarz, Ulrike M K Böttcher, Suranjana Guha and F Ulrich Hartl
  The EMBO Journal (2008), 27, - 301, doi:10.1038/sj.emboj.7601964

Table of Contents

Volume 27, Number 1 09 January 2008

EMBO Members Review

MHC class II molecules on the move for successful antigen presentation FREE

Subject Categories:

Articles

A versatile interaction platform on the Mex67–Mtr2 receptor creates an overlap between mRNA and ribosome export FREE

Subject Categories:

Parallel topology of genetically fused EmrE homodimers FREE

Subject Categories:

Real-time detection reveals that effectors couple dynamin's GTP-dependent conformational changes to the membrane FREE

Subject Categories:

Spatial recruitment and activation of the Fes kinase by ezrin promotes HGF-induced cell scattering FREE

Subject Category:

Cell cycle-specific UNG2 phosphorylations regulate protein turnover, activity and association with RPA EMBO Open

Subject Categories:

Intermediate-affinity LFA-1 binds -actinin-1 to control migration at the leading edge of the T cell EMBO Open

Subject Categories:

JNK phosphorylates synaptotagmin-4 and enhances Ca2+-evoked release FREE

Subject Categories:

14-3-3 Proteins recognize a histone code at histone H3 and are required for transcriptional activation FREE

Subject Category:

RSC regulates nucleosome positioning at Pol II genes and density at Pol III genes FREE

Subject Category:

Cell-cycle regulation of cohesin stability along fission yeast chromosomes FREE

Subject Categories:

Intrasplicing coordinates alternative first exons with alternative splicing in the protein 4.1R gene FREE

Subject Category:

Cdc2p controls the forkhead transcription factor Fkh2p by phosphorylation during sexual differentiation in fission yeast FREE

Subject Category:

p166, a link between the trypanosome mitochondrial DNA and flagellum, mediates genome segregation FREE

Subject Category:

Sequential recruitment of the repair factors during NER: the role of XPG in initiating the resynthesis step FREE

Subject Category:

Two distinct mechanisms of silencing by the KvDMR1 imprinting control region FREE

Subject Categories:

Invalidation of TASK1 potassium channels disrupts adrenal gland zonation and mineralocorticoid homeostasis FREE

Subject Categories:

Neural recognition molecules CHL1 and NB-3 regulate apical dendrite orientation in the neocortex via PTP FREE

Subject Category:

Hsp90-mediated cytosolic refolding of exogenous proteins internalized by dendritic cells EMBO Open

Subject Categories:

Impaired liver regeneration in Nrf2 knockout mice: role of ROS-mediated insulin/IGF-1 resistance FREE

Subject Categories:

Lipids revert inert A amyloid fibrils to neurotoxic protofibrils that affect learning in mice EMBO Open

Subject Categories:

Structure-guided identification of a new catalytic motif of oligosaccharyltransferase FREE

Subject Categories:

The post-rigor structure of myosin VI and implications for the recovery stroke FREE

Subject Category:

Molecular basis of the C-terminal tail-to-tail assembly of the sarcomeric filament protein myomesin FREE

Subject Categories:

Structure and functional analysis of the IGF-II/IGF2R interaction FREE

Subject Categories:

Dimerization of FIR upon FUSE DNA binding suggests a mechanism of c-myc inhibition EMBO Open

Subject Categories:

Crystal structure of human XLF/Cernunnos reveals unexpected differences from XRCC4 with implications for NHEJ EMBO Open

Subject Categories:

Retraction

TRiC/CCT cooperates with different upstream chaperones in the folding of distinct protein classes FREE

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Volume 27, Number 1
09 January 2008

JNK phosphorylates synaptotagmin-4 and enhances Ca²⁺-evoked release FREE