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Welcome to EMBO reports

The EMBO reports special issue on The Future Of Our Species is available online. Global climate change, space exploration, disease, genetic enhancement, evolution and extended lifespans are just some of the topics addressed by the authors. Humankind is facing both its greatest challenges and its biggest opportunities; how we deal with each may well determine the future of our species.

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EMBO reports Journal Cover
Volume 9, Number 10
(October 2008)
ISSN 1469 - 221X
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EMBO Reports
Science's twin taboos
Frame that gene
Science and Society in full...
Protein neddylation in the spotlight
Regulation of Wnt secretion
Reviews in full...
IL-33 attachment to chromatin
The Girard lab continues its work on nuclear IL-33 and shows a curious mimicry between the cytokine and Kaposi's sarcoma associated herpesvirus. IL-33 uses a short peptide to bind the acidic pocket of nucleosomes in a similar manner to the KSHV LANA anchoring of the viral genome to mitotic chromosomes.

PP4 is a γH2AX phosphatase
Phosphorylation of histone H2AX is a crucial event in the DNA double-strand breaks response. However, its dephosphorylation is less understood and here Durocher et al unravel the contribution of PP4 to dephosphorylation of H2AX and its role at the G2/M checkpoint arrest.

p38α prevents liver failure
Using p38α deficient mice livers, this study demonstrates the role of the MAPK in protecting the liver from LPS/TNF-induced failure. By blocking JNK, p38α collaborates with IKK2 to prevent endotoxin-induced hepatocyte apoptosis.

Scientific Reports in full...
EMBO reports SupplementScience and Society Special Issue
Volume 9, July 2008

The future of our species

Click here to view Special Issue

The EMBO Journal
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The EMBO Journal is a print and online publication dedicated to providing a variety of complete and rapidly published articles in all areas of molecular biology. It is one of the most highly cited journals, reflected in its latest impact factor of 8.662*

*Journal Citation Reports, Thomson Reuters 2008

MEMBRANES & TRANSPORT | PLANT BIOLOGY
 Rice OsHKT2;1 transporter mediates large Na+ influx component into K+-starved roots for growth

MICROBIOLOGY & PATHOGENS
 HIV-1 DNA Flap formation promotes uncoating of the pre-integration complex at the nuclear pore

13 October 2008
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