EMBO Reports EMBO Reports http://www.nature.com/emboj/current_issue/ Nature Publishing Group en Copyright © 2009 European Molecular Biology Organization EMBO Reports 1469-221X 1469-3178 Nature Publishing Group Copyright © 2009 European Molecular Biology Organization permissions@nature.com EMBO Reports http://www.nature.com/embor/images/embo_reports_logo.gif http://www.nature.com/emboj/ A letter to Darwin http://dx.doi.org/10.1038/embor.2008.239 Frank Gannon A letter to Darwin Frank Gannon doi:10.1038/embor.2008.239 EMBO Reports 10, 1 (2009) 2009-01-01 EMBO Reports 2009-01-01 10 1 editorial 1 The state of h index research. Is the h index the ideal way to measure research performance? http://dx.doi.org/10.1038/embor.2008.233 Lutz Bornmann & Hans-Dieter Daniel The state of h index research. Is the h index the ideal way to measure research performance? Lutz Bornmann Hans-Dieter Daniel doi:10.1038/embor.2008.233 EMBO Reports 10, 2 (2009) 2009-01-01 EMBO Reports 2009-01-01 10 1 science and society 2 6 Managing the unimaginable. Regulatory responses to the challenges posed by synthetic biology and synthetic genomics http://dx.doi.org/10.1038/embor.2008.232 Gabrielle N Samuel, Michael J Selgelid & Ian Kerridge Managing the unimaginable. Regulatory responses to the challenges posed by synthetic biology and synthetic genomics Gabrielle N Samuel Michael J Selgelid Ian Kerridge doi:10.1038/embor.2008.232 EMBO Reports 10, 7 (2009) 2009-01-01 EMBO Reports 2009-01-01 10 1 science and society 7 11 A decade of stem-cell research. An interview with John Gearhart, Director of the Institute for Regenerative Medicine at the University of Pennsylvania, USA http://dx.doi.org/10.1038/embor.2008.235 Howard Wolinsky A decade of stem-cell research. An interview with John Gearhart, Director of the Institute for Regenerative Medicine at the University of Pennsylvania, USA Howard Wolinsky doi:10.1038/embor.2008.235 EMBO Reports 10, 12 (2009) 2009-01-01 EMBO Reports 2009-01-01 10 1 science and society 12 16 The good, the bad and the ugly red tape of biomedical research. How could regulators lower bureaucratic hurdles in clinical research without compromising the safety of patients? http://dx.doi.org/10.1038/embor.2008.237 Mark Greener The good, the bad and the ugly red tape of biomedical research. How could regulators lower bureaucratic hurdles in clinical research without compromising the safety of patients? Mark Greener doi:10.1038/embor.2008.237 EMBO Reports 10, 17 (2009) 2009-01-01 EMBO Reports 2009-01-01 10 1 science and society 17 20 Reading the metabolic fine print. The application of metabolomics to diagnostics, drug research and nutrition might be integral to improved health and personalized medicine http://dx.doi.org/10.1038/embor.2008.236 Philip Hunter Reading the metabolic fine print. The application of metabolomics to diagnostics, drug research and nutrition might be integral to improved health and personalized medicine Philip Hunter doi:10.1038/embor.2008.236 EMBO Reports 10, 20 (2009) 2009-01-01 EMBO Reports 2009-01-01 10 1 science and society 20 23 Science-in-theatre-in-science http://dx.doi.org/10.1038/embor.2008.234 Suresh Rattan Science-in-theatre-in-science Suresh Rattan doi:10.1038/embor.2008.234 EMBO Reports 10, 24 (2009) 2009-01-01 EMBO Reports 2009-01-01 10 1 science and society 24 Epigenetics and the control of multicellularity. Workshop on Chromatin at the Nexus of Cell Division and Differentiation http://dx.doi.org/10.1038/embor.2008.226 Gunter Reuter & Giacomo Cavalli Epigenetics and the control of multicellularity. Workshop on Chromatin at the Nexus of Cell Division and Differentiation Gunter Reuter Giacomo Cavalli doi:10.1038/embor.2008.226 EMBO Reports 10, 25 (2009) 2009-01-01 EMBO Reports 2009-01-01 10 1 review 25 29 MHC molecules lead many lives. Workshop on MHC Class I Molecules at the interface between Biology & Medicine http://dx.doi.org/10.1038/embor.2008.215 Paul Bowness, Steve Caplan & Michael Edidin MHC molecules lead many lives. Workshop on MHC Class I Molecules at the interface between Biology & Medicine Paul Bowness Steve Caplan Michael Edidin doi:10.1038/embor.2008.215 EMBO Reports 10, 30 (2009) 2009-01-01 EMBO Reports 2009-01-01 10 1 review 30 34 Old and new faces of the nucleolus. Workshop on the Nucleolus and Disease http://dx.doi.org/10.1038/embor.2008.230 Lesley A Stark & Michael Taliansky Old and new faces of the nucleolus. 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Sonja Sollner, Markus Schober, Andrea Wagner, Anna Prem, Lucie Lorkova, Bruce A Palfey, Michael Groll & Peter Macheroux Quinone reductase acts as a redox switch of the 20S yeast proteasome Sonja Sollner Markus Schober Andrea Wagner Anna Prem Lucie Lorkova Bruce A Palfey Michael Groll Peter Macheroux doi:10.1038/embor.2008.218 EMBO Reports 10, 65 (2009) 2009-01-01 EMBO Reports 2009-01-01 10 1 scientific report 65 70 Cellular senescence and organismal ageing in the absence of p21CIP1/WAF1 in ku80-/- mice http://dx.doi.org/10.1038/embor.2008.220 Bo Zhao, Erica K Benson, Ruifang Qiao, Xing Wang, Sunchin Kim, James J Manfredi, Sam W Lee & Stuart A Aaronson Cellular senescence and organismal ageing in the absence of p21CIP1/WAF1 in ku80-/- mice Bo Zhao Erica K Benson Ruifang Qiao Xing Wang Sunchin Kim James J Manfredi Sam W Lee Stuart A Aaronson doi:10.1038/embor.2008.220 EMBO Reports 10, 71 (2009) 2009-01-01 EMBO Reports 2009-01-01 10 1 scientific report 71 78 SHARP1/DEC2 inhibits 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expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease http://dx.doi.org/10.1038/embor.2008.222 Nikolai D Belyaev, Natalia N Nalivaeva, Natalia Z Makova & Anthony J Turner Neprilysin gene expression requires binding of the amyloid precursor protein intracellular domain to its promoter: implications for Alzheimer disease Nikolai D Belyaev Natalia N Nalivaeva Natalia Z Makova Anthony J Turner doi:10.1038/embor.2008.222 EMBO Reports 10, 94 (2009) 2009-01-01 EMBO Reports 2009-01-01 10 1 scientific report 94 100 Blm10 binds to pre-activated proteasome core particles with open gate conformation http://dx.doi.org/10.1038/embor.2008.225 Andrea Lehmann, Katharina Jechow & Cordula Enenkel Blm10 binds to pre-activated proteasome core particles with open gate conformation Andrea Lehmann Katharina Jechow Cordula Enenkel doi:10.1038/embor.2008.225 EMBO Reports 10, 101 (2009) 2009-01-01 EMBO Reports 2009-01-01 10 1 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