Gene Therapy http://www.nature.com/gt/current_issue/ Nature Publishing Group en Copyright © Nature Publishing Group Gene Therapy 0969-7128 Copyright © Nature Publishing Group permissions@nature.com Gene Therapy http://www.nature.com/aj/images/logos_b_o_w/gt.gif http://www.nature.com/gt/ Cystic fibrosis: Ferreting with fibroblasts for cystic fibrosis http://dx.doi.org/10.1038/gt.2008.155 Cystic fibrosis: Ferreting with fibroblasts for cystic fibrosis

Gene Therapy 16, 1 (January 2009). doi:10.1038/gt.2008.155

Authors: U Griesenbach & E W F W Alton

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Cystic fibrosis: Ferreting with fibroblasts for cystic fibrosis U Griesenbach E W F W Alton doi:10.1038/gt.2008.155 Gene Therapy 16, 1 (January 2009) October 2, 2008 Gene Therapy October 2, 2008 16 1 1 2
Progress & Prospects: Gene therapy in aging http://dx.doi.org/10.1038/gt.2008.166 Progress & Prospects: Gene therapy in aging

Gene Therapy 16, 3 (January 2009). doi:10.1038/gt.2008.166

Authors: S I S Rattan & R Singh

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Progress & Prospects: Gene therapy in aging S I S Rattan R Singh doi:10.1038/gt.2008.166 Gene Therapy 16, 3 (January 2009) November 13, 2008 Gene Therapy November 13, 2008 16 1 3 9
Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization http://dx.doi.org/10.1038/gt.2008.115 Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization

Gene Therapy 16, 10 (January 2009). doi:10.1038/gt.2008.115

Authors: P Pechan, H Rubin, M Lukason, J Ardinger, E DuFresne, W W Hauswirth, S C Wadsworth & A Scaria

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Novel anti-VEGF chimeric molecules delivered by AAV vectors for inhibition of retinal neovascularization P Pechan H Rubin M Lukason J Ardinger E DuFresne W W Hauswirth S C Wadsworth A Scaria doi:10.1038/gt.2008.115 Gene Therapy 16, 10 (January 2009) July 17, 2008 Gene Therapy July 17, 2008 16 1 10 16
Redox proteins thioredoxin 1 and thioredoxin 2 support retinal ganglion cell survival in experimental glaucoma http://dx.doi.org/10.1038/gt.2008.126 Redox proteins thioredoxin 1 and thioredoxin 2 support retinal ganglion cell survival in experimental glaucoma

Gene Therapy 16, 17 (January 2009). doi:10.1038/gt.2008.126

Authors: Y Munemasa, J H Ahn, J M K Kwong, J Caprioli & N Piri

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Redox proteins thioredoxin 1 and thioredoxin 2 support retinal ganglion cell survival in experimental glaucoma Y Munemasa J H Ahn J M K Kwong J Caprioli N Piri doi:10.1038/gt.2008.126 Gene Therapy 16, 17 (January 2009) August 14, 2008 Gene Therapy August 14, 2008 16 1 17 25
Herpes simplex virus vector-mediated delivery of neurturin rescues erectile dysfunction of cavernous nerve injury http://dx.doi.org/10.1038/gt.2008.132 Herpes simplex virus vector-mediated delivery of neurturin rescues erectile dysfunction of cavernous nerve injury

Gene Therapy 16, 26 (January 2009). doi:10.1038/gt.2008.132

Authors: R Kato, D Wolfe, C H Coyle, J B Wechuck, P Tyagi, T Tsukamoto, J B Nelson, J C Glorioso, M B Chancellor & N Yoshimura

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Herpes simplex virus vector-mediated delivery of neurturin rescues erectile dysfunction of cavernous nerve injury R Kato D Wolfe C H Coyle J B Wechuck P Tyagi T Tsukamoto J B Nelson J C Glorioso M B Chancellor N Yoshimura doi:10.1038/gt.2008.132 Gene Therapy 16, 26 (January 2009) July 31, 2008 Gene Therapy July 31, 2008 16 1 26 33
Transplantation of BMSCs expressing hPDGF-A/hBD2 promotes wound healing in rats with combined radiation-wound injury http://dx.doi.org/10.1038/gt.2008.133 Transplantation of BMSCs expressing hPDGF-A/hBD2 promotes wound healing in rats with combined radiation-wound injury

Gene Therapy 16, 34 (January 2009). doi:10.1038/gt.2008.133

Authors: L Hao, J Wang, Z Zou, G Yan, S Dong, J Deng, X Ran, Y Feng, C Luo, Y Wang & T Cheng

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Transplantation of BMSCs expressing hPDGF-A/hBD2 promotes wound healing in rats with combined radiation-wound injury L Hao J Wang Z Zou G Yan S Dong J Deng X Ran Y Feng C Luo Y Wang T Cheng doi:10.1038/gt.2008.133 Gene Therapy 16, 34 (January 2009) August 14, 2008 Gene Therapy August 14, 2008 16 1 34 42
A small regulatory element from chromosome 19 enhances liver-specific gene expression http://dx.doi.org/10.1038/gt.2008.134 A small regulatory element from chromosome 19 enhances liver-specific gene expression

Gene Therapy 16, 43 (January 2009). doi:10.1038/gt.2008.134

Authors: C Li, M Hirsch, P Carter, A Asokan, X Zhou, Z Wu & R J Samulski

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A small regulatory element from chromosome 19 enhances liver-specific gene expression C Li M Hirsch P Carter A Asokan X Zhou Z Wu R J Samulski doi:10.1038/gt.2008.134 Gene Therapy 16, 43 (January 2009) August 14, 2008 Gene Therapy August 14, 2008 16 1 43 51
Gene delivery into ischemic myocardium by double-targeted lipoplexes with anti-myosin antibody and TAT peptide http://dx.doi.org/10.1038/gt.2008.135 Gene delivery into ischemic myocardium by double-targeted lipoplexes with anti-myosin antibody and TAT peptide

Gene Therapy 16, 52 (January 2009). doi:10.1038/gt.2008.135

Authors: Y T Ko, W C Hartner, A Kale & V P Torchilin

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Gene delivery into ischemic myocardium by double-targeted lipoplexes with anti-myosin antibody and TAT peptide Y T Ko W C Hartner A Kale V P Torchilin doi:10.1038/gt.2008.135 Gene Therapy 16, 52 (January 2009) August 14, 2008 Gene Therapy August 14, 2008 16 1 52 59
Enhancing transduction of the liver by adeno-associated viral vectors http://dx.doi.org/10.1038/gt.2008.137 Enhancing transduction of the liver by adeno-associated viral vectors

Gene Therapy 16, 60 (January 2009). doi:10.1038/gt.2008.137

Authors: A C Nathwani, M Cochrane, J McIntosh, C Y C Ng, J Zhou, J T Gray & A M Davidoff

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Enhancing transduction of the liver by adeno-associated viral vectors A C Nathwani M Cochrane J McIntosh C Y C Ng J Zhou J T Gray A M Davidoff doi:10.1038/gt.2008.137 Gene Therapy 16, 60 (January 2009) August 14, 2008 Gene Therapy August 14, 2008 16 1 60 69
Doxycycline-controlled splicing modulation by regulated antisense U7 snRNA expression cassettes http://dx.doi.org/10.1038/gt.2008.138 Doxycycline-controlled splicing modulation by regulated antisense U7 snRNA expression cassettes

Gene Therapy 16, 70 (January 2009). doi:10.1038/gt.2008.138

Authors: J Marquis, S S Kämpfer, L Angehrn & D Schümperli

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Doxycycline-controlled splicing modulation by regulated antisense U7 snRNA expression cassettes J Marquis S S Kämpfer L Angehrn D Schümperli doi:10.1038/gt.2008.138 Gene Therapy 16, 70 (January 2009) August 14, 2008 Gene Therapy August 14, 2008 16 1 70 77
Microvascular free tissue transfer for gene delivery: in vivo evaluation of different routes of plasmid and adenoviral delivery http://dx.doi.org/10.1038/gt.2008.140 Microvascular free tissue transfer for gene delivery: in vivo evaluation of different routes of plasmid and adenoviral delivery

Gene Therapy 16, 78 (January 2009). doi:10.1038/gt.2008.140

Authors: V K Agrawal, K M Copeland, Y Barbachano, A Rahim, R Seth, C L White, M Hingorani, C M Nutting, M Kelly, P Harris, H Pandha, A A Melcher, R G Vile, C Porter & K J Harrington

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Microvascular free tissue transfer for gene delivery: in vivo evaluation of different routes of plasmid and adenoviral delivery V K Agrawal K M Copeland Y Barbachano A Rahim R Seth C L White M Hingorani C M Nutting M Kelly P Harris H Pandha A A Melcher R G Vile C Porter K J Harrington doi:10.1038/gt.2008.140 Gene Therapy 16, 78 (January 2009) September 11, 2008 Gene Therapy September 11, 2008 16 1 78 92
Lentiviral gene transfer to reduce atherosclerosis progression by long-term CC-chemokine inhibition http://dx.doi.org/10.1038/gt.2008.141 Lentiviral gene transfer to reduce atherosclerosis progression by long-term CC-chemokine inhibition

Gene Therapy 16, 93 (January 2009). doi:10.1038/gt.2008.141

Authors: C A Bursill, E McNeill, L Wang, O C Hibbitt, R Wade-Martins, D J Paterson, D R Greaves & K M Channon

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Lentiviral gene transfer to reduce atherosclerosis progression by long-term CC-chemokine inhibition C A Bursill E McNeill L Wang O C Hibbitt R Wade-Martins D J Paterson D R Greaves K M Channon doi:10.1038/gt.2008.141 Gene Therapy 16, 93 (January 2009) September 18, 2008 Gene Therapy September 18, 2008 16 1 93 102
Extended release of adenovirus from silica implants in vitro and in vivo http://dx.doi.org/10.1038/gt.2008.142 Extended release of adenovirus from silica implants in vitro and in vivo

Gene Therapy 16, 103 (January 2009). doi:10.1038/gt.2008.142

Authors: L Kangasniemi, M Koskinen, M Jokinen, M Toriseva, R Ala-Aho, V-M Kähäri, H Jalonen, S Ylä-Herttuala, H Moilanen, U-H Stenman, I Diaconu, A Kanerva, S Pesonen, T Hakkarainen & A Hemminki

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Extended release of adenovirus from silica implants in vitro and in vivo L Kangasniemi M Koskinen M Jokinen M Toriseva R Ala-Aho V-M Kähäri H Jalonen S Ylä-Herttuala H Moilanen U-H Stenman I Diaconu A Kanerva S Pesonen T Hakkarainen A Hemminki doi:10.1038/gt.2008.142 Gene Therapy 16, 103 (January 2009) August 28, 2008 Gene Therapy August 28, 2008 16 1 103 110
Transgene optimization significantly improves SIN vector titers, gp91phox expression and reconstitution of superoxide production in X-CGD cells http://dx.doi.org/10.1038/gt.2008.143 Transgene optimization significantly improves SIN vector titers, gp91phox expression and reconstitution of superoxide production in X-CGD cells

Gene Therapy 16, 111 (January 2009). doi:10.1038/gt.2008.143

Authors: B Moreno-Carranza, M Gentsch, S Stein, A Schambach, G Santilli, E Rudolf, M F Ryser, S Haria, A J Thrasher, C Baum, S Brenner & M Grez

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Transgene optimization significantly improves SIN vector titers, gp91phox expression and reconstitution of superoxide production in X-CGD cells B Moreno-Carranza M Gentsch S Stein A Schambach G Santilli E Rudolf M F Ryser S Haria A J Thrasher C Baum S Brenner M Grez doi:10.1038/gt.2008.143 Gene Therapy 16, 111 (January 2009) September 11, 2008 Gene Therapy September 11, 2008 16 1 111 118
Microwave irradiation enhances gene and oligonucleotide delivery and induces effective exon skipping in myoblasts http://dx.doi.org/10.1038/gt.2008.144 Microwave irradiation enhances gene and oligonucleotide delivery and induces effective exon skipping in myoblasts

Gene Therapy 16, 119 (January 2009). doi:10.1038/gt.2008.144

Authors: T J Doran, P J Lu, G S Vanier, M J Collins, B Wu & Q L Lu

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Microwave irradiation enhances gene and oligonucleotide delivery and induces effective exon skipping in myoblasts T J Doran P J Lu G S Vanier M J Collins B Wu Q L Lu doi:10.1038/gt.2008.144 Gene Therapy 16, 119 (January 2009) September 11, 2008 Gene Therapy September 11, 2008 16 1 119 126
Polymeric gene delivery of ischemia-inducible VEGF significantly attenuates infarct size and apoptosis following myocardial infarct http://dx.doi.org/10.1038/gt.2008.146 Polymeric gene delivery of ischemia-inducible VEGF significantly attenuates infarct size and apoptosis following myocardial infarct

Gene Therapy 16, 127 (January 2009). doi:10.1038/gt.2008.146

Authors: J W Yockman, D Choi, M G Whitten, C W Chang, A Kastenmeier, H Erickson, A Albanil, M Lee, S W Kim & D A Bull

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Polymeric gene delivery of ischemia-inducible VEGF significantly attenuates infarct size and apoptosis following myocardial infarct J W Yockman D Choi M G Whitten C W Chang A Kastenmeier H Erickson A Albanil M Lee S W Kim D A Bull doi:10.1038/gt.2008.146 Gene Therapy 16, 127 (January 2009) September 11, 2008 Gene Therapy September 11, 2008 16 1 127 135
PET imaging of thymidine kinase gene expression in the liver of non-human primates following systemic delivery of an adenoviral vector http://dx.doi.org/10.1038/gt.2008.122 PET imaging of thymidine kinase gene expression in the liver of non-human primates following systemic delivery of an adenoviral vector

Gene Therapy 16, 136 (January 2009). doi:10.1038/gt.2008.122

Authors: A Fontanellas, S Hervas-Stubbs, A Sampedro, M Collantes, A Azpilicueta, I Mauleón, A Pañeda, G Quincoces, J Prieto, I Melero & I Peñuelas

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PET imaging of thymidine kinase gene expression in the liver of non-human primates following systemic delivery of an adenoviral vector A Fontanellas S Hervas-Stubbs A Sampedro M Collantes A Azpilicueta I Mauleón A Pañeda G Quincoces J Prieto I Melero I Peñuelas doi:10.1038/gt.2008.122 Gene Therapy 16, 136 (January 2009) July 31, 2008 Gene Therapy July 31, 2008 16 1 136 141
Prevention of interferon-stimulated gene expression using microRNA-designed hairpins http://dx.doi.org/10.1038/gt.2008.123 Prevention of interferon-stimulated gene expression using microRNA-designed hairpins

Gene Therapy 16, 142 (January 2009). doi:10.1038/gt.2008.123

Authors: M Bauer, N Kinkl, A Meixner, E Kremmer, M Riemenschneider, H Förstl, T Gasser & M Ueffing

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Prevention of interferon-stimulated gene expression using microRNA-designed hairpins M Bauer N Kinkl A Meixner E Kremmer M Riemenschneider H Förstl T Gasser M Ueffing doi:10.1038/gt.2008.123 Gene Therapy 16, 142 (January 2009) August 14, 2008 Gene Therapy August 14, 2008 16 1 142 147
Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2-/-γc-/-) mouse model http://dx.doi.org/10.1038/gt.2008.124 Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2-/-γc-/-) mouse model

Gene Therapy 16, 148 (January 2009). doi:10.1038/gt.2008.124

Authors: O ter Brake, N Legrand, K J von Eije, M Centlivre, H Spits, K Weijer, B Blom & B Berkhout

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Evaluation of safety and efficacy of RNAi against HIV-1 in the human immune system (Rag-2-/-γc-/-) mouse model O ter Brake N Legrand K J von Eije M Centlivre H Spits K Weijer B Blom B Berkhout doi:10.1038/gt.2008.124 Gene Therapy 16, 148 (January 2009) July 31, 2008 Gene Therapy July 31, 2008 16 1 148 153
An efficient transfection method for mouse embryonic stem cells http://dx.doi.org/10.1038/gt.2008.125 An efficient transfection method for mouse embryonic stem cells

Gene Therapy 16, 154 (January 2009). doi:10.1038/gt.2008.125

Authors: B S Ko, T C Chang, S K Shyue, Y C Chen & J Y Liou

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An efficient transfection method for mouse embryonic stem cells B S Ko T C Chang S K Shyue Y C Chen J Y Liou doi:10.1038/gt.2008.125 Gene Therapy 16, 154 (January 2009) July 31, 2008 Gene Therapy July 31, 2008 16 1 154 158
SIVMAC Vpx improves the transduction of dendritic cells with nonintegrative HIV-1-derived vectors http://dx.doi.org/10.1038/gt.2008.128 SIVMAC Vpx improves the transduction of dendritic cells with nonintegrative HIV-1-derived vectors

Gene Therapy 16, 159 (January 2009). doi:10.1038/gt.2008.128

Authors: G Berger, C Goujon, J-L Darlix & A Cimarelli

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SIVMAC Vpx improves the transduction of dendritic cells with nonintegrative HIV-1-derived vectors G Berger C Goujon J-L Darlix A Cimarelli doi:10.1038/gt.2008.128 Gene Therapy 16, 159 (January 2009) July 31, 2008 Gene Therapy July 31, 2008 16 1 159 163