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GLYCOBIOLOGY OF THE IMMUNE SYSTEM
- Focus issue:
- October 2008 Volume 86, No 7
Carbohydrates are involved in a range of interactions related to immune responses. This collection of recent review and research articles represents our current understanding of the roles glycans play in activating the adaptive and innate immune responses.
Library
Distribution of the αGal- and the non-αGal T-antigens in the pig kidney: potential targets for rejection in pig-to-man xenotransplantation FREE
Svend Kirkeby and Hanne B Mikkelsen
Immunology and Cell Biology (2008) 86, 363-371; doi:10.1038/icb.2008.1
Perlecan: a major IL-2-binding proteoglycan in murine spleen FREE
John D Miller, Elliott T Stevens, Deandra R Smith, Thomas N Wight and Lucile E Wrenshall
Immunology and Cell Biology (2008) 86, 192-199; doi:10.1038/sj.icb.7100128
Autoimmunity: Altered self-N-glycans trigger innate-mediated autoimmunity FREE
Steven J Van Dyken and Richard M Locksley
Immunology and Cell Biology (2007) 85, 572-574; doi:10.1038/sj.icb.7100122
Toll-like receptors: structural pieces of a curve-shaped puzzle FREE
Trevor Huyton, Jamie Rossjohn and Matthew Wilce
Immunology and Cell Biology (2007) 85, 406-410; doi:10.1038/sj.icb.7100089
Critical functions of N-glycans in L-selectin-mediated lymphocyte homing and recruitment
Junya Mitoma, Xingfeng Bao, Bronislawa Petryanik, Patrick Schaerli, Jean-Marc Gauguet, Shin-Yi Yu, Hiroto Kawashima, Hideo Saito, Kazuaki Ohtsubo, Jamey D Marth, Kay-Hooi Khoo, Ulrich H von Andrian, John B Lowe and Minoru Fukuda
Nature Immunology 8, 409-418 (2007) | doi:10.1038/ni1442
The sweet and sour of cancer: glycans as novel therapeutic targets
Mark M Fuster and Jeffrey D Esko
Nature Reviews Cancer 5, 526-542 (July 2005) | doi:10.1038/nrc1649
Glycans in cancer and inflammation — potential for therapeutics and diagnostics
Danielle H Dube and Carolyn R Bertozzi
Nature Reviews Drug Discovery 4, 477-488 (June 2005) | doi:10.1038/nrd1751
Metabolic labeling of glycans with azido sugars and subsequent glycan-profiling and visualization via Staudinger ligation
Scott T Laughlin and Carolyn Bertozzi
Nature Protocols 2, 2930-2944 (2007) | doi:10.1038/nprot.2007.422
Mucin-type O-glycans in human colon and breast cancer: glycodynamics and functions
Inka Brockhausen
EMBO reports 7, 6, 599-604 (2006) | doi:10.1038/sj.embor.7400705
Glycomics: an integrated systems approach to structure-function relationships of glycans
Rahul Raman, S Raguram, Ganesh Venkataraman, James C Paulson and Ram Sasisekharan
Nature Methods 2, 817-824 (2005) | doi:10.1038/nmeth807
CD1d-lipid-antigen recognition by the semi-invariant NKT T-cell receptor
Natalie A Borg, Kwok S Wun, Lars Kjer-Nielsen, Matthew C J Wilce, Daniel G Pellicci, Ruide Koh, Gurdyal S Besra, Mandvi Bharadwaj, Dale I Godfrey, James McCluskey and Jamie Rossjohn
Nature 448, 44-49 (5 July 2007) | doi:10.1038/nature05907
The crystal structure of human CD1d with and without αgalactosylceramide
Michael Koch, Victoria S Stronge, Dawn Shepherd, Stephan D Gadola, Bini Mathew, Gerd Ritter, Alan R Fersht, Gurdyal S Besra, Richard R Schmidt, E Yvonne Jones and Vincenzo Cerundolo
Nature Immunology 6, 819-826 (2005) | doi:10.1038/ni1225
