TABLE OF CONTENTS
Volume 23, Issue 7 (July 2009)
Spotlight Introduction |
Spotlight Reviews |
Original Articles |
Letters to the Editor |
Corrigendum
Spotlight Editorial
Genomic technologies in leukemia and lymphoma: a review series
A A Ferrando
Leukemia 23: 1207; doi:10.1038/leu.2009.81
Spotlight Introduction
Introduction to the genomics spotlight
N Killmann
Leukemia 23: 1208; doi:10.1038/leu.2009.97
Spotlight Reviews
Genome-wide profiling of genetic alterations in acute lymphoblastic leukemia: recent insights and future directions
C G Mullighan and J R Downing
Leukemia 23: 1209-1218; advance online publication, February 26, 2009; doi:10.1038/leu.2009.18
Toward a systems biology approach to investigate cellular networks in normal and malignant B cells
K Basso
Leukemia 23: 1219-1225; advance online publication, February 5, 2009; doi:10.1038/leu.2009.4
Genomic approaches to small molecule discovery
K Stegmaier
Leukemia 23: 1226-1235; advance online publication, March 5, 2009; doi:10.1038/leu.2009.29
Genomic tools for dissecting oncogenic transcriptional networks in human leukemia
T Palomero and A A Ferrando
Leukemia 23: 1236-1242; advance online publication, January 22, 2009; doi:10.1038/leu.2008.394
Chromatin maps, histone modifications and leukemia
T Neff and S A Armstrong
Leukemia 23: 1243-1251; advance online publication, March 26, 2009; doi:10.1038/leu.2009.40
Deletion 5q in myelodysplastic syndrome: a paradigm for the study of hemizygous deletions in cancer
B L Ebert
Leukemia 23: 1252-1256; advance online publication, March 26, 2009; doi:10.1038/leu.2009.53
The role of microRNA in human leukemia: a review
S Yendamuri and G A Calin
Leukemia 23: 1257-1263; advance online publication, January 15, 2009; doi:10.1038/leu.2008.382
Original Articles
Therapy
Induction death and treatment-related mortality in first remission of children with acute lymphoblastic leukemia: a population-based analysis of the Austrian Berlin-Frankfurt-Münster study group
C Prucker, A Attarbaschi, C Peters, M N Dworzak, U Pötschger, C Urban, F-M Fink, B Meister, K Schmitt, O A Haas, H Gadner and G Mann on behalf of the Austrian Berlin-Frankfurt-Münster (BFM) Study Group
Leukemia 23: 1264-1269; advance online publication, February 12, 2009; doi:10.1038/leu.2009.12
Acute Leukemias
GATA-1 and GATA-2 binding to 3' enhancer of WT1 gene is essential for its transcription in acute leukemia and solid tumor cell lines
A Furuhata, M Murakami, H Ito, S Gao, K Yoshida, S Sobue, R Kikuchi, T Iwasaki, A Takagi, T Kojima, M Suzuki, A Abe, T Naoe and T Murate
Leukemia 23: 1270-1277; advance online publication, February 12, 2009; doi:10.1038/leu.2009.13
Effects of activating NK cell receptor expression and NK cell reconstitution on the outcomes of unrelated donor hematopoietic cell transplantation for hematologic malignancies
B M Triplett, E M Horwitz, R Iyengar, V Turner, M S Holladay, K Gan, F G Behm and W Leung
Leukemia 23: 1278-1287; advance online publication, February 12, 2009; doi:10.1038/leu.2009.21
Myelodysplasias
Altered naive and memory CD4+ T-cell homeostasis and immunosenescence characterize younger patients with myelodysplastic syndrome
J X Zou, D E Rollison, D Boulware, D-T Chen, E M Sloand, L V Pfannes, J J Goronzy, F Bai, J S Painter, S Wei, D Cosgrove, A F List and P K Epling-Burnette
Leukemia 23: 1288-1296; advance online publication, March 12, 2009; doi:10.1038/leu.2009.14
Phase II study of rabbit anti-thymocyte globulin, cyclosporine and granulocyte colony-stimulating factor in patients with aplastic anemia and myelodysplastic syndrome
R Garg, S Faderl, G Garcia-Manero, J Cortes, C Koller, X Huang, S York, S Pierce, M Brandt, M Beran, G Borthakur, H Kantarjian and F Ravandi
Leukemia 23: 1297-1302; advance online publication, February 26, 2009; doi:10.1038/leu.2009.28
Acute myeloid leukemia bearing t(7;11)(p15;p15) is a distinct cytogenetic entity with poor outcome and a distinct mutation profile: comparative analysis of 493 adult patients
W-C Chou, C-Y Chen, H-A Hou, L-I Lin, J-L Tang, M Yao, W Tsay, B-S Ko, S-J Wu, S-Y Huang, S-C Hsu, Y-C Chen, Y-N Huang, M-H Tseng, C-F Huang and H-F Tien
Leukemia 23: 1303-1310; advance online publication, February 19, 2009; doi:10.1038/leu.2009.25
Oncogenes, Fusion Genes and Tumor Suppressor Genes
Continuous Fli-1 expression plays an essential role in the proliferation and survival of F-MuLV-induced erythroleukemia and human erythroleukemia
J-W Cui, L M Vecchiarelli-Federico, Y-J Li, G-J Wang and Y Ben-David
Leukemia 23: 1311-1319; advance online publication, March 12, 2009; doi:10.1038/leu.2009.20
Lymphoma
Cyclin D1 as a universally expressed mantle cell lymphoma-associated tumor antigen for immunotherapy
M Wang, L Sun, J Qian, X Han, L Zhang, P Lin, Z Cai and Q Yi
Leukemia 23: 1320-1328; advance online publication, February 19, 2009; doi:10.1038/leu.2009.19
CMC-544 (inotuzumab ozogamicin), an anti-CD22 immuno-conjugate of calicheamicin, alters the levels of target molecules of malignant B-cells
A Takeshita, N Yamakage, K Shinjo, T Ono, I Hirano, S Nakamura, K Shigeno, T Tobita, M Maekawa, H Kiyoi, T Naoe, K Ohnishi, Y Sugimoto and R Ohno
Leukemia 23: 1329-1336; advance online publication, April 16, 2009; doi:10.1038/leu.2009.77
Myeloma
Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: high response rates in a phase II clinical trial
C B Reeder, D E Reece, V Kukreti, C Chen, S Trudel, J Hentz, B Noble, N A Pirooz, J E Spong, J G Piza, V H J Zepeda, J R Mikhael, J F Leis, P L Bergsagel, R Fonseca and A K Stewart
Leukemia 23: 1337-1341; advance online publication, February 19, 2009; doi:10.1038/leu.2009.26
Letters to the Editor
Successful induction therapy with decitabine in refractory childhood acute lymphoblastic leukemia
L Yánez, A Bermúdez, C Richard, E Bureo and A Iriondo
Leukemia 23: 1342-1343; advance online publication, March 26, 2009; doi:10.1038/leu.2009.58
Detection of mutant TET2 in myeloid malignancies other than myeloproliferative neoplasms: CMML, MDS, MDS/MPN and AML
A Tefferi, K-H Lim, O Abdel-Wahab, T L Lasho, J Patel, M M Patnaik, C A Hanson, A Pardanani, D G Gilliland and R L Levine
Leukemia 23: 1343-1345; advance online publication, March 19, 2009; doi:10.1038/leu.2009.59
Functional characterization of an activating TEK mutation in acute myeloid leukemia: a cellular context-dependent activating mutation
J W Tyner, M L Rutenberg-Schoenberg, H Erickson, S G Willis, T O'Hare, M W Deininger, B J Druker and M M Loriaux
Leukemia 23: 1345-1348; advance online publication, April 2, 2009; doi:10.1038/leu.2009.66
Reduced folate carrier and methylenetetrahydrofolate reductase gene polymorphisms: associations with clinical outcome in childhood acute lymphoblastic leukemia
L J Ashton, A J Gifford, E Kwan, A Lingwood, D T T Lau, G M Marshall, M Haber and M D Norris
Leukemia 23: 1348-1351; advance online publication, April 2, 2009; doi:10.1038/leu.2009.67
Detection of p53 dysfunction in chronic lymphocytic leukaemia cells through multiplex quantification of p53 target gene induction
R Mous, A Jaspers, D M P Luijks, C H M Mellink, M H J van Oers, A P Kater and E Eldering
Leukemia 23: 1352-1355; advance online publication, April 2, 2009; doi:10.1038/leu.2009.71
Immunoglobulin and T-cell receptor gene rearrangements as PCR-based targets are stable markers for monitoring minimal residual disease in acute lymphoblastic leukemia after stem cell transplantation
H Kreyenberg, C Eckert, Y Yarkin, M Reising, A Willasch, R Handgretinger, B Kremens, A von Stackelberg, G Henze, T Klingebiel and P Bader
Leukemia 23: 1355-1358; advance online publication, April 9, 2009; doi:10.1038/leu.2009.72
LRRFIP1, a new FGFR1 partner gene associated with 8p11 myeloproliferative syndrome
G Soler, S Nusbaum, B Varet, E A Macintyre, M Vekemans, S P Romana and I Radford-Weiss
Leukemia 23: 1359-1361; advance online publication, April 16, 2009; doi:10.1038/leu.2009.79
Flow cytometric identification of acute myeloid leukemia with limited differentiation and NPM1 type A mutation: a new biologically defined entity
W Kern, C Haferlach, U Bacher, T Haferlach and S Schnittger
Leukemia 23: 1361-1364; advance online publication, April 16, 2009; doi:10.1038/leu.2009.84
A novel pedigree with heterozygous germline RUNX1 mutation causing familial MDS-related AML: can these families serve as a multistep model for leukemic transformation?
T Ripperger, D Steinemann, G Göhring, J Finke, C M Niemeyer, B Strahm and B Schlegelberger
Leukemia 23: 1364-1366; advance online publication, April 23, 2009; doi:10.1038/leu.2009.87
Recombinant interferon alpha (rIFN
-2b) may retard progression of early primary myelofibrosis
R T Silver and K Vandris
Leukemia 23: 1366-1369; advance online publication, May 14, 2009; doi:10.1038/leu.2009.90
Cytoplasmic mutated nucleophosmin (NPM1) in blast crisis of chronic myeloid leukaemia
P P Piccaluga, E Sabattini, F Bacci, C Agostinelli, S Righi, F Salmi, N Testoni, S Paolini, F Castagnetti, G Martinelli, B Falini and S A Pileri
Leukemia 23: 1370-1371; advance online publication, May 7, 2009; doi:10.1038/leu.2009.95
Corrigendum
CMC-544 (inotuzumab ozogamicin), an anti-CD22 immuno-conjugate of calicheamicin, alters the levels of target molecules of malignant B-cells FREE
A Takeshita, N Yamakage, K Shinjo, T Ono, I Hirano, S Nakamura, K Shigeno, T Tobita, M Maekawa, H Kiyoi, T Naoe, K Ohnishi, Y Sugimoto and R Ohno
Leukemia 23: 1372; doi:10.1038/leu.2009.115
