SPOTLIGHT ON MOLECULAR TARGETED THERAPY
2002
EDITORIAL
Spotlight on molecular targeted therapy: introduction
MS Sheikh
REVIEWS
Sphingosine 1-phosphate as a therapeutic agent
S Spiegel and R Kolesnick
The proteasome: a novel target for cancer chemotherapy
JB Almond and GM Cohen
Hsp-90-associated oncoproteins: multiple targets of geldanamycin and its analogs
MV Blagosklonny
Classical and novel retinoids: their targets in cancer therapy
JA Fontana and AK Rishi
Large-scale gene expression analysis in molecular target discovery
MS Orr and U Scherf
Identification of novel targets for cancer therapy using expression proteomics
SM Hanash, J Madoz-Gurpide and DE Misek
The Raf/MEK/ERK signal transduction cascade as a target for chemotherapeutic intervention in leukaemia
JT Lee Jr and JA McCubrey
HMG-CoA reductase inhibitors and the malignant cell: the statin family of drugs as triggers of tumor-specific apoptosis
WW-L Wong, J Dimitroulakos, MD Minden and L Penn
Developmental Therapeutics Program at the NCI: molecular target and drug discovery process
M Monga and EA Sausville
Myeloid Differentiation (MyD)/Growth Arrest DNA Damage (GADD) genes in tumor suppression, immunity and inflammation
DA Liebermann and B Hoffman
Nuclear transcription factor- B as a target for cancer drug development
A Garg and BB Aggarwal
