ADVANCE ONLINE PUBLICATION
The latest research papers, published online ahead of print. These online versions are definitive and may be cited using the digital object identifier (DOI).
About advance online publication
December 30 2008 |
December 23 2008 |
December 16 2008 |
December 9 2008 |
December 2 2008 |
November 25 2008 |
November 11 2008 |
November 4 2008 |
October 28 2008 |
October 21 2008 |
October 14 2008 |
September 30 2008 |
September 23 2008 |
September 16 2008 |
September 9 2008 |
September 2 2008 |
August 26 2008 |
August 12 2008 |
July 29 2008 |
July 22 2008 |
July 15 2008 |
July 8 2008 |
July 1 2008 |
June 24 2008 |
June 3 2008 |
May 27 2008 |
May 20 2008 |
May 13 2008 |
May 6 2008 |
April 22 2008 |
April 15 2008 |
April 1 2008 |
March 25 2008 |
March 18 2008 |
March 11 2008 |
March 4 2008 |
February 26 2008 |
February 19 2008 |
February 12 2008 |
February 5 2008 |
January 29 2008 |
January 15 2008 |
January 8 2008 |
October 16 2007 |
November 21 2006
January 6 2009
Original Articles
A SNAP25 promoter variant is associated with early-onset bipolar disorder and a high expression level in brain
B Etain, A Dumaine, F Mathieu, F Chevalier, C Henry, J-P Kahn, J Deshommes, F Bellivier, M Leboyer and S Jamain
Mol Psychiatry advance online publication, January 6, 2009; doi:10.1038/mp.2008.148
Examination of the current top candidate genes for AD in a genome-wide association study
T M Feulner, S M Laws, P Friedrich, S Wagenpfeil, S H R Wurst, C Riehle, K A Kuhn, M Krawczak, S Schreiber, S Nikolaus, H Förstl, A Kurz and M Riemenschneider
Mol Psychiatry advance online publication, January 6, 2009; doi:10.1038/mp.2008.141
Variations in tryptophan hydroxylase 2 linked to decreased serotonergic activity are associated with elevated risk for metabolic syndrome in depression
S Kloiber, M A Kohli, T Brueckl, S Ripke, M Ising, M Uhr, A Menke, P G Unschuld, S Horstmann, D Salyakina, B Muller-Myhsok, E B Binder, F Holsboer and S Lucae
Mol Psychiatry advance online publication, January 6, 2009; doi:10.1038/mp.2008.142
December 30 2008
Immediate Communication
Singleton deletions throughout the genome increase risk of bipolar disorder
D Zhang, L Cheng, Y Qian, N Alliey-Rodriguez, J R Kelsoe, T Greenwood, C Nievergelt, T B Barrett, R McKinney, N Schork, E N Smith, C Bloss, J Nurnberger, H J Edenberg, T Foroud, W Sheftner, W B Lawson, E A Nwulia, M Hipolito, W Coryell, J Rice, W Byerley, F McMahon, T G Schulze, W Berrettini, J B Potash, P L Belmonte, P P Zandi, M G McInnis, S Zöllner, D Craig, S Szelinger, D Koller, S L Christian, C Liu and E S Gershon
Mol Psychiatry advance online publication, December 30, 2008; doi:10.1038/mp.2008.144
Original Article
Meta-analysis of 32 genome-wide linkage studies of schizophrenia
M Y M Ng, D F Levinson, S V Faraone, B K Suarez, L E DeLisi, T Arinami, B Riley, T Paunio, A E Pulver, Irmansyah, P A Holmans, M Escamilla, D B Wildenauer, N M Williams, C Laurent, B J Mowry, L M Brzustowicz, M Maziade, P Sklar, D L Garver, G R Abecasis, B Lerer, M D Fallin, H M D Gurling, P V Gejman, E Lindholm, H W Moises, W Byerley, E M Wijsman, P Forabosco, M T Tsuang, H-G Hwu, Y Okazaki, K S Kendler, B Wormley, A Fanous, D Walsh, F A O'Neill, L Peltonen, G Nestadt, V K Lasseter, K Y Liang, G M Papadimitriou, D G Dikeos, S G Schwab, M J Owen, M C O'Donovan, N Norton, E Hare, H Raventos, H Nicolini, M Albus, W Maier, V L Nimgaonkar, L Terenius, J Mallet, M Jay, S Godard, D Nertney, M Alexander, R R Crowe, J M Silverman, A S Bassett, M-A Roy, C Mérette, C N Pato, M T Pato, J Louw Roos, Y Kohn, D Amann-Zalcenstein, G Kalsi, A McQuillin, D Curtis, J Brynjolfson, T Sigmundsson, H Petursson, A R Sanders, J Duan, E Jazin, M Myles-Worsley, M Karayiorgou and C M Lewis
Mol Psychiatry advance online publication, December 30, 2008; doi:10.1038/mp.2008.135
December 23 2008
Original Article
Genome-wide association study of recurrent major depressive disorder in two European case–control cohorts
P Muglia, F Tozzi, N W Galwey, C Francks, R Upmanyu, X Q Kong, A Antoniades, E Domenici, J Perry, S Rothen, C L Vandeleur, V Mooser, G Waeber, P Vollenweider, M Preisig, S Lucae, B Müller-Myhsok, F Holsboer, L T Middleton and A D Roses
Mol Psychiatry advance online publication, December 23, 2008; doi:10.1038/mp.2008.131
December 16 2008
Immediate Communication
Two variants in Ankyrin 3 (ANK3) are independent genetic risk factors for bipolar disorder
T G Schulze, S D Detera-Wadleigh, N Akula, A Gupta, L Kassem, J Steele, J Pearl, J Strohmaier, R Breuer, M Schwarz, P Propping, M M Nöthen, S Cichon, J Schumacher, NIMH Genetics Initiative Bipolar Disorder ConsortiumM Rietschel and F J McMahon
Mol Psychiatry advance online publication, December 16, 2008; doi:10.1038/mp.2008.134
December 9 2008
Immediate Communications
Gene-wide analyses of genome-wide association data sets: evidence for multiple common risk alleles for schizophrenia and bipolar disorder and for overlap in genetic risk
V Moskvina, N Craddock, P Holmans, I Nikolov, J S Pahwa, E Green, Wellcome Trust Case Control ConsortiumM J Owen and M C O'Donovan
Mol Psychiatry advance online publication, December 9, 2008; doi:10.1038/mp.2008.133
Genome-wide association for major depressive disorder: a possible role for the presynaptic protein piccolo
P F Sullivan, E J C de Geus, G Willemsen, M R James, J H Smit, T Zandbelt, V Arolt, B T Baune, D Blackwood, S Cichon, W L Coventry, K Domschke, A Farmer, M Fava, S D Gordon, Q He, A C Heath, P Heutink, F Holsboer, W J Hoogendijk, J J Hottenga, Y Hu, M Kohli, D Lin, S Lucae, D J MacIntyre, W Maier, K A McGhee, P McGuffin, G W Montgomery, W J Muir, W A Nolen, M M Nöthen, R H Perlis, K Pirlo, D Posthuma, M Rietschel, P Rizzu, A Schosser, A B Smit, J W Smoller, J-Y Tzeng, R van Dyck, M Verhage, F G Zitman, N G Martin, N R Wray, D I Boomsma and B W J H Penninx
Mol Psychiatry advance online publication, December 9, 2008; doi:10.1038/mp.2008.125
Original Articles
Targeted disruption of serine racemase affects glutamatergic neurotransmission and behavior
A C Basu, G E Tsai, C-L Ma, J T Ehmsen, A K Mustafa, L Han, Z I Jiang, M A Benneyworth, M P Froimowitz, N Lange, S H Snyder, R Bergeron and J T Coyle
Mol Psychiatry advance online publication, December 9, 2008; doi:10.1038/mp.2008.130
Effect of abstinence challenge on brain function and cognition in smokers differs by COMT genotype
J Loughead, E P Wileyto, J N Valdez, P Sanborn, K Tang, A A Strasser, K Ruparel, R Ray, R C Gur and C Lerman
Mol Psychiatry advance online publication, December 9, 2008; doi:10.1038/mp.2008.132
Gene discovery through imaging genetics: identification of two novel genes associated with schizophrenia
S G Potkin, J A Turner, J A Fallon, A Lakatos, D B Keator, G Guffanti and F Macciardi FBIRN
Mol Psychiatry advance online publication, December 9, 2008; doi:10.1038/mp.2008.127
December 2 2008
Original Article
A threonine to isoleucine missense mutation in the pericentriolar material 1 gene is strongly associated with schizophrenia
S R Datta, A McQuillin, M Rizig, E Blaveri, S Thirumalai, G Kalsi, J Lawrence, N J Bass, V Puri, K Choudhury, J Pimm, C Crombie, G Fraser, N Walker, D Curtis, M Zvelebil, A Pereira, R Kandaswamy, D St Clair and H M D Gurling
Mol Psychiatry advance online publication, December 2, 2008; doi:10.1038/mp.2008.128
November 25 2008
Original Article
Developmental etiology for neuroanatomical and cognitive deficits in mice overexpressing G
s, a G-protein subunit genetically linked to schizophrenia
M P Kelly, J M Stein, C G Vecsey, C Favilla, X Yang, S F Bizily, M F Esposito, G Wand, S J Kanes and T Abel
Mol Psychiatry advance online publication, November 25, 2008; doi:10.1038/mp.2008.124
November 11 2008
Original Article
Differential effects on T-cell function following exposure to serum from schizophrenia smokers
M Herberth, D N Krzyszton, D Koethe, M R Craddock, E Bulger, E Schwarz, P Guest, F M Leweke and S Bahn
Mol Psychiatry advance online publication, November 11, 2008; doi:10.1038/mp.2008.120
November 4 2008
Original Articles
The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling
J M Bessa, D Ferreira, I Melo, F Marques, J J Cerqueira, J A Palha, O F X Almeida and N Sousa
Mol Psychiatry advance online publication, November 4, 2008; doi:10.1038/mp.2008.119
Review and meta-analysis of antidepressant pharmacogenetic findings in major depressive disorder
M Kato and A Serretti
Mol Psychiatry advance online publication, November 4, 2008; doi:10.1038/mp.2008.116
Chronic imipramine but not bupropion increases arachidonic acid signaling in rat brain: is this related to 'switching' in bipolar disorder?
H-J Lee, J S Rao, L Chang, S I Rapoport and H-W Kim
Mol Psychiatry advance online publication, November 4, 2008; doi:10.1038/mp.2008.117
Spatiotemporal dynamics of the expression of estrogen receptors in the postnatal mouse brain
N Sugiyama, S Andersson, R Lathe, X Fan, P Alonso-Magdalena, T Schwend, I Nalvarte, M Warner and J-Å Gustafsson
Mol Psychiatry advance online publication, November 4, 2008; doi:10.1038/mp.2008.118
October 28 2008
Feature Review
Immunization in Alzheimer's disease: naïve hope or realistic clinical potential?
J K Foster, G Verdile, K A Bates and R N Martins
Mol Psychiatry advance online publication, October 28, 2008; doi:10.1038/mp.2008.115
Original Articles
Lower CSF oxytocin concentrations in women with a history of childhood abuse
C Heim, L J Young, D J Newport, T Mletzko, A H Miller and C B Nemeroff
Mol Psychiatry advance online publication, October 28, 2008; doi:10.1038/mp.2008.112
Genome-wide association scan for five major dimensions of personality
A Terracciano, S Sanna, M Uda, B Deiana, G Usala, F Busonero, A Maschio, M Scally, N Patriciu, W-M Chen, M A Distel, E P Slagboom, D I Boomsma, S Villafuerte, E 
liwerska, M Burmeister, N Amin, A C J W Janssens, C M van Duijn, D Schlessinger, G R Abecasis and P T Costa Jr
Mol Psychiatry advance online publication, October 28, 2008; doi:10.1038/mp.2008.113
October 21 2008
Original Article
Polymorphisms in SREBF1 and SREBF2, two antipsychotic-activated transcription factors controlling cellular lipogenesis, are associated with schizophrenia in German and Scandinavian samples
S Le Hellard, T W Mühleisen, S Djurovic, J Fernø, Z Ouriaghi, M Mattheisen, C Vasilescu, M B Raeder, T Hansen, J Strohmaier, A Georgi, F F Brockschmidt, I Melle, I Nenadic, H Sauer, M Rietschel, M M Nöthen, T Werge, O A Andreassen, S Cichon and V M Steen
Mol Psychiatry advance online publication, October 21, 2008; doi:10.1038/mp.2008.110
October 14 2008
Original Article
Meta-analysis of the BDNF Val66Met polymorphism in major depressive disorder: effects of gender and ethnicity
M Verhagen, A van der Meij, P A M van Deurzen, J G E Janzing, A Arias-Vásquez, J K Buitelaar and B Franke
Mol Psychiatry advance online publication, October 14, 2008; doi:10.1038/mp.2008.109
September 30 2008
Original Article
Glial pathology in an animal model of depression: reversal of stress-induced cellular, metabolic and behavioral deficits by the glutamate-modulating drug riluzole
M Banasr, G M I Chowdhury, R Terwilliger, S S Newton, R S Duman, K L Behar and G Sanacora
Mol Psychiatry advance online publication, September 30, 2008; doi:10.1038/mp.2008.106
September 23 2008
Original Article
Amyloid-
causes memory impairment by disturbing the JAK2/STAT3 axis in hippocampal neurons
T Chiba, M Yamada, J Sasabe, K Terashita, M Shimoda, M Matsuoka and S Aiso
Mol Psychiatry advance online publication, September 23, 2008; doi:10.1038/mp.2008.105
Analysis of 10 independent samples provides evidence for association between schizophrenia and a SNP flanking fibroblast growth factor receptor 2
M C O'Donovan, N Norton, H Williams, T Peirce, V Moskvina, I Nikolov, M Hamshere, L Carroll, L Georgieva, S Dwyer, P Holmans, J L Marchini, C C A Spencer, B Howie, H-T Leung, I Giegling, A M Hartmann, H-J Möller, D W Morris, Y Shi, G Feng, P Hoffmann, P Propping, C Vasilescu, W Maier, M Rietschel, S Zammit, J Schumacher, E M Quinn, T G Schulze, N Iwata, M Ikeda, A Darvasi, S Shifman, L He, J Duan, A R Sanders, D F Levinson, R Adolfsson, U Ösby, L Terenius, E G Jönsson, S Cichon, M M Nöthen, M Gill, A P Corvin, D Rujescu, P V Gejman, G Kirov, N Craddock, N M Williams, M J Owen and Molecular Genetics of Schizophrenia Collaboration
Mol Psychiatry advance online publication, September 23, 2008; doi:10.1038/mp.2008.108
September 16 2008
Feature Review
Clearance mechanisms of Alzheimer's amyloid- peptide: implications for therapeutic design and diagnostic tests
K A Bates, G Verdile, Q-X Li, D Ames, P Hudson, C L Masters and R N Martins
Mol Psychiatry advance online publication, September 16, 2008; doi:10.1038/mp.2008.96
Original Articles
Population-based linkage analysis of schizophrenia and bipolar case–control cohorts identifies a potential susceptibility locus on 19q13
C Francks, F Tozzi, A Farmer, J B Vincent, D Rujescu, D St Clair and P Muglia
Mol Psychiatry advance online publication, September 16, 2008; doi:10.1038/mp.2008.100
Slitrk1-deficient mice display elevated anxiety-like behavior and noradrenergic abnormalities
K Katayama, K Yamada, V G Ornthanalai, T Inoue, M Ota, N P Murphy and J Aruga
Mol Psychiatry advance online publication, September 16, 2008; doi:10.1038/mp.2008.97
September 9 2008
Original Articles
Suicidal ideation and suicide attempts in the United States: 1991–1992 and 2001–2002
E Baca-Garcia, M M Perez-Rodriguez, K M Keyes, M A Oquendo, D S Hasin, B F Grant and C Blanco
Mol Psychiatry advance online publication, September 9, 2008; doi:10.1038/mp.2008.98
Association of maternal dopamine transporter genotype with negative parenting: evidence for gene x environment interaction with child disruptive behavior
S S Lee, A Chronis-Tuscano, K Keenan, W E Pelham, J Loney, C A Van Hulle, E H Cook and B B Lahey
Mol Psychiatry advance online publication, September 9, 2008; doi:10.1038/mp.2008.102
Behavioral immunization: immunity to self-antigens contributes to psychological stress resilience
G M Lewitus and M Schwartz
Mol Psychiatry advance online publication, September 9, 2008; doi:10.1038/mp.2008.103
September 2 2008
Original Article
Correlation analysis between genome-wide expression profiles and cytoarchitectural abnormalities in the prefrontal cortex of psychiatric disorders
S Kim and M J Webster
Mol Psychiatry advance online publication, September 2, 2008; doi:10.1038/mp.2008.99
August 26 2008
Original Article
The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication
A M Ruscio, D J Stein, W T Chiu and R C Kessler
Mol Psychiatry advance online publication, August 26, 2008; doi:10.1038/mp.2008.94
August 12 2008
Feature Review
Potential adverse effects of amphetamine treatment on brain and behavior: a review
S M Berman, R Kuczenski, J T McCracken and E D London
Mol Psychiatry advance online publication, August 12, 2008; doi:10.1038/mp.2008.90
July 29 2008
Original Articles
Soluble amyloid precursor proteins in the cerebrospinal fluid as novel potential biomarkers of Alzheimer's disease: a multicenter study
P Lewczuk, H Kamrowski-Kruck, O Peters, I Heuser, F Jessen, J Popp, K Bürger, H Hampel, L Frölich, S Wolf, B Prinz, H Jahn, Ch Luckhaus, R Perneczky, M Hüll, J Schröder, H Kessler, J Pantel, H-J Gertz, H-W Klafki, H Kölsch, U Reulbach, H Esselmann, J M Maler, M Bibl, J Kornhuber and J Wiltfang
Mol Psychiatry advance online publication, July 29, 2008; doi:10.1038/mp.2008.84
Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6
O Riccio, G Potter, C Walzer, P Vallet, G Szabó, L Vutskits, J Z Kiss and A G Dayer
Mol Psychiatry advance online publication, July 29, 2008; doi:10.1038/mp.2008.89
Panic disorder is associated with the serotonin transporter gene (SLC6A4) but not the promoter region (5-HTTLPR)
L J Strug, R Suresh, A J Fyer, A Talati, P B Adams, W Li, S E Hodge, T C Gilliam and M M Weissman
Mol Psychiatry advance online publication, July 29, 2008; doi:10.1038/mp.2008.79
July 22 2008
Original Articles
The association between smoking and subsequent suicide-related outcomes in the National Comorbidity Survey panel sample
R C Kessler, G Borges, N Sampson, M Miller and M K Nock
Mol Psychiatry advance online publication, July 22, 2008; doi:10.1038/mp.2008.78
Proton MRS in twin pairs discordant for schizophrenia
E S Lutkenhoff, T G van Erp, M A Thomas, S Therman, M Manninen, M O Huttunen, J Kaprio, J Lönnqvist, J O'Neill and T D Cannon
Mol Psychiatry advance online publication, July 22, 2008; doi:10.1038/mp.2008.87
July 15 2008
Original Article
Minor physical anomalies in autism: a meta-analysis
H M Ozgen, J W Hop, J J Hox, F A Beemer and H van Engeland
Mol Psychiatry advance online publication, July 15, 2008; doi:10.1038/mp.2008.75
July 8 2008
Original Articles
Altered calcium homeostasis in autism-spectrum disorders: evidence from biochemical and genetic studies of the mitochondrial aspartate/glutamate carrier AGC1
L Palmieri, V Papaleo, V Porcelli, P Scarcia, L Gaita, R Sacco, J Hager, F Rousseau, P Curatolo, B Manzi, R Militerni, C Bravaccio, S Trillo, C Schneider, R Melmed, M Elia, C Lenti, M Saccani, T Pascucci, S Puglisi-Allegra, K-L Reichelt and A M Persico
Mol Psychiatry advance online publication, July 8, 2008; doi:10.1038/mp.2008.63
Brain surface contraction mapped in first-episode schizophrenia: a longitudinal magnetic resonance imaging study
D Sun, G W Stuart, M Jenkinson, S J Wood, P D McGorry, D Velakoulis, T G M van Erp, P M Thompson, A W Toga, D J Smith, T D Cannon and C Pantelis
Mol Psychiatry advance online publication, July 8, 2008; doi:10.1038/mp.2008.34
July 1 2008
Original Article
Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype
N Craddock, L Jones, I R Jones, G Kirov, E K Green, D Grozeva, V Moskvina, I Nikolov, M L Hamshere, D Vukcevic, S Caesar, K Gordon-Smith, C Fraser, E Russell, N Norton, G Breen, D St Clair, D A Collier, A H Young, I N Ferrier, A Farmer, P McGuffin, P A Holmans, Wellcome Trust Case Control Consortium (WTCCC)P Donnelly, M J Owen and M C O'Donovan
Mol Psychiatry advance online publication, July 1, 2008; doi:10.1038/mp.2008.66
June 24 2008
Original Article
The complex global pattern of genetic variation and linkage disequilibrium at catechol-O-methyltransferase
N Mukherjee, K K Kidd, A J Pakstis, W C Speed, H Li, Z Tarnok, C Barta, S L B Kajuna and J R Kidd
Mol Psychiatry advance online publication, June 24, 2008; doi:10.1038/mp.2008.64
June 3 2008
Original Articles
Association of the NPAS3 gene and five other loci with response to the antipsychotic iloperidone identified in a whole genome association study
C Lavedan, L Licamele, S Volpi, J Hamilton, C Heaton, K Mack, R Lannan, A Thompson, C D Wolfgang and M H Polymeropoulos
Mol Psychiatry advance online publication, June 3, 2008; doi:10.1038/mp.2008.56
Interferon- effects on diurnal hypothalamic–pituitary–adrenal axis activity: relationship with proinflammatory cytokines and behavior
C L Raison, A S Borisov, B J Woolwine, Breanne Massung, G Vogt and A H Miller
Mol Psychiatry advance online publication, June 3, 2008; doi:10.1038/mp.2008.58
Whole genome association study identifies polymorphisms associated with QT prolongation during iloperidone treatment of schizophrenia
S Volpi, C Heaton, K Mack, J B Hamilton, R Lannan, C D Wolfgang, L Licamele, M H Polymeropoulos and C Lavedan
Mol Psychiatry advance online publication, June 3, 2008; doi:10.1038/mp.2008.52
May 27 2008
Original Article
Integrative proteomic analysis of the nucleus accumbens in rhesus monkeys following cocaine self-administration
N S Tannu, L L Howell and S E Hemby
Mol Psychiatry advance online publication, May 27, 2008; doi:10.1038/mp.2008.53
May 20 2008
Original Articles
Deep brain stimulation of the ventral internal capsule/ventral striatum for obsessive-compulsive disorder: worldwide experience
B D Greenberg, L A Gabriels, D A Malone Jr, A R Rezai, G M Friehs, M S Okun, N A Shapira, K D Foote, P R Cosyns, C S Kubu, P F Malloy, S P Salloway, J E Giftakis, M T Rise, A G Machado, K B Baker, P H Stypulkowski, W K Goodman, S A Rasmussen and B J Nuttin
Mol Psychiatry advance online publication, May 20, 2008; doi:10.1038/mp.2008.55
Genetic variants in AVPR1A linked to autism predict amygdala activation and personality traits in healthy humans
A Meyer-Lindenberg, B Kolachana, B Gold, A Olsh, K K Nicodemus, V Mattay, M Dean and D R Weinberger
Mol Psychiatry advance online publication, May 20, 2008; doi:10.1038/mp.2008.54
May 13 2008
Original Article
Heavy marijuana users show increased serum apolipoprotein C-III levels: evidence from proteomic analyses
S Jayanthi, S Buie, S Moore, R I Herning, W Better, N M Wilson, C Contoreggi and J L Cadet
Mol Psychiatry advance online publication, May 13, 2008; doi:10.1038/mp.2008.50
May 6 2008
Original Article
Functional polymorphisms in the interleukin-6 and serotonin transporter genes, and depression and fatigue induced by interferon- and ribavirin treatment
S J Bull, P Huezo-Diaz, E B Binder, J F Cubells, G Ranjith, C Maddock, C Miyazaki, N Alexander, M Hotopf, A J Cleare, S Norris, E Cassidy, K J Aitchison, A H Miller and C M Pariante
Mol Psychiatry advance online publication, May 6, 2008; doi:10.1038/mp.2008.48
April 22 2008
Original Articles
Tph2 gene variants modulate response control processes in adult ADHD patients and healthy individuals
C G Baehne, A-C Ehlis, M M Plichta, A Conzelmann, P Pauli, C Jacob, L Gutknecht, K-P Lesch and A J Fallgatter
Mol Psychiatry advance online publication, April 22, 2008; doi:10.1038/mp.2008.39
Expression of -synuclein is increased in the hippocampus of rats with high levels of innate anxiety
S Chiavegatto, G S Izidio, A Mendes-Lana, I Aneas, T A Freitas, A S Torrão, I M Conceição, L R G Britto and A Ramos
Mol Psychiatry advance online publication, April 22, 2008; doi:10.1038/mp.2008.43
Sociodemographic and psychopathologic predictors of first incidence of DSM-IV substance use, mood and anxiety disorders: results from the Wave 2 National Epidemiologic Survey on Alcohol and Related Conditions
B F Grant, R B Goldstein, S P Chou, B Huang, F S Stinson, D A Dawson, T D Saha, S M Smith, A J Pulay, R P Pickering, W J Ruan and W M Compton
Mol Psychiatry advance online publication, April 22, 2008; doi:10.1038/mp.2008.41
April 15 2008
Original Articles
Ontogeny of sensorimotor gating and immune impairment induced by prenatal immune challenge in rats: implications for the etiopathology of schizophrenia
E Romero, C Guaza, B Castellano and J Borrell
Mol Psychiatry advance online publication, April 15, 2008; doi:10.1038/mp.2008.44
Genetic variation in the CHRNA5 gene affects mRNA levels and is associated with risk for alcohol dependence
J C Wang, R Grucza, C Cruchaga, A L Hinrichs, S Bertelsen, J P Budde, L Fox, E Goldstein, O Reyes, N Saccone, S Saccone, X Xuei, K Bucholz, S Kuperman, J Nurnberger Jr, J P Rice, M Schuckit, J Tischfield, V Hesselbrock, B Porjesz, H J Edenberg, L J Bierut and A M Goate
Mol Psychiatry advance online publication, April 15, 2008; doi:10.1038/mp.2008.42
April 1 2008
Original Article
A genome-wide panel of congenic mice reveals widespread epistasis of behavior quantitative trait loci
G D Gale, R D Yazdi, A H Khan, A J Lusis, R C Davis and D J Smith
Mol Psychiatry advance online publication, April 1, 2008; doi:10.1038/mp.2008.4
March 25 2008
Original Article
Influence of escitalopram treatment on 5-HT1A receptor binding in limbic regions in patients with anxiety disorders
C Spindelegger, R Lanzenberger, W Wadsak, L K Mien, P Stein, M Mitterhauser, U Moser, A Holik, L Pezawas, K Kletter and S Kasper
Mol Psychiatry advance online publication, March 25, 2008; doi:10.1038/mp.2008.35
March 18 2008
Original Article
Glutamate as a spectroscopic marker of hippocampal structural plasticity is elevated in long-term euthymic bipolar patients on chronic lithium therapy and correlates inversely with diurnal cortisol
M Colla, F Schubert, M Bubner, J O Heidenreich, M Bajbouj, F Seifert, A Luborzewski, I Heuser and G Kronenberg
Mol Psychiatry advance online publication, March 18, 2008; doi:10.1038/mp.2008.26
March 11 2008
Original Articles
Family-based association testing strongly implicates DRD2 as a risk gene for schizophrenia in Han Chinese from Taiwan
S J Glatt, S V Faraone, J A Lasky-Su, T Kanazawa, H-G Hwu and M T Tsuang
Mol Psychiatry advance online publication, March 11, 2008; doi:10.1038/mp.2008.30
A genome-wide association study in 574 schizophrenia trios using DNA pooling
G Kirov, I Zaharieva, L Georgieva, V Moskvina, I Nikolov, S Cichon, A Hillmer, D Toncheva, M J Owen and M C O'Donovan
Mol Psychiatry advance online publication, March 11, 2008; doi:10.1038/mp.2008.33
March 4 2008
Original Articles
DISC1 association, heterogeneity and interplay in schizophrenia and bipolar disorder
W Hennah, P Thomson, A McQuillin, N Bass, A Loukola, A Anjorin, D Blackwood, D Curtis, I J Deary, S E Harris, E T Isometsä, J Lawrence, J Lönnqvist, W Muir, A Palotie, T Partonen, T Paunio, E Pylkkö, M Robinson, P Soronen, K Suominen, J Suvisaari, S Thirumalai, D St Clair, H Gurling, L Peltonen and D Porteous
Mol Psychiatry advance online publication, March 4, 2008; doi:10.1038/mp.2008.22
Involvement of the PRKCB1 gene in autistic disorder: significant genetic association and reduced neocortical gene expression
C Lintas, R Sacco, K Garbett, K Mirnics, R Militerni, C Bravaccio, P Curatolo, B Manzi, C Schneider, R Melmed, M Elia, T Pascucci, S Puglisi-Allegra, K-L Reichelt and A M Persico
Mol Psychiatry advance online publication, March 4, 2008; doi:10.1038/mp.2008.21
Interacting haplotypes at the NPAS3 locus alter risk of schizophrenia and bipolar disorder
B S Pickard, A Christoforou, P A Thomson, A Fawkes, K L Evans, S W Morris, D J Porteous, D H Blackwood and W J Muir
Mol Psychiatry advance online publication, March 4, 2008; doi:10.1038/mp.2008.24
Decreased cortical muscarinic receptors define a subgroup of subjects with schizophrenia
E Scarr, T F Cowie, S Kanellakis, S Sundram, C Pantelis and B Dean
Mol Psychiatry advance online publication, March 4, 2008; doi:10.1038/mp.2008.28
Effects of the G(-656)A variant on CREB1 promoter activity in a neuronal cell line: Interactions with gonadal steroids and stress
G S Zubenko and H B Hughes III
Mol Psychiatry advance online publication, March 4, 2008; doi:10.1038/mp.2008.23
February 26 2008
Original Articles
Identifying blood biomarkers for mood disorders using convergent functional genomics
H Le-Niculescu, S M Kurian, N Yehyawi, C Dike, S D Patel, H J Edenberg, M T Tsuang, D R Salomon, J I Nurnberger Jr and A B Niculescu
Mol Psychiatry advance online publication, February 26, 2008; doi:10.1038/mp.2008.11
Assessment of circadian function in fibroblasts of patients with bipolar disorder
S Yang, H P A Van Dongen, K Wang, W Berrettini and M Bu
an
Mol Psychiatry advance online publication, February 26, 2008; doi:10.1038/mp.2008.10
February 19 2008
Original Articles
A high-density SNP genome-wide linkage scan in a large autism extended pedigree
K Allen-Brady, J Miller, N Matsunami, J Stevens, H Block, M Farley, L Krasny, C Pingree, J Lainhart, M Leppert, W M McMahon and H Coon
Mol Psychiatry advance online publication, February 19, 2008; doi:10.1038/mp.2008.14
Impairment in role functioning in mental and chronic medical disorders in the United States: results from the National Comorbidity Survey Replication
B G Druss, I Hwang, M Petukhova, N A Sampson, P S Wang and R C Kessler
Mol Psychiatry advance online publication, February 19, 2008; doi:10.1038/mp.2008.13
A common polymorphism in serotonin receptor 1B mRNA moderates regulation by miR-96 and associates with aggressive human behaviors
K P Jensen, J Covault, T S Conner, H Tennen, H R Kranzler and H M Furneaux
Mol Psychiatry advance online publication, February 19, 2008; doi:10.1038/mp.2008.15
February 12 2008
Original Article
Evidence for HTR1A and LHPP as interacting genetic risk factors in major depression
C D Neff, V Abkevich, J C L Packer, Y Chen, J Potter, R Riley, C Davenport, J DeGrado Warren, S Jammulapati, A Bhathena, W S Choi, P E Kroeger, R E Metzger, A Gutin, M H Skolnick, D Shattuck and D A Katz
Mol Psychiatry advance online publication, February 12, 2008; doi:10.1038/mp.2008.8
February 5 2008
Original Article
Metabonomic analysis identifies molecular changes associated with the pathophysiology and drug treatment of bipolar disorder
M J Lan, G A McLoughlin, J L Griffin, T M Tsang, J T J Huang, P Yuan, H Manji, E Holmes and S Bahn
Mol Psychiatry advance online publication, February 5, 2008; doi:10.1038/sj.mp.4002130
January 29 2008
Original Articles
Oxytocin as a natural antipsychotic: a study using oxytocin knockout mice
H K Caldwell, S L Stephens and W S Young III
Mol Psychiatry advance online publication, January 29, 2008; doi:10.1038/sj.mp.4002150
The extracellular signal-regulated kinase pathway contributes to the control of behavioral excitement
S R Engel, T K Creson, Y Hao, Y Shen, S Maeng, T Nekrasova, G E Landreth, H K Manji and G Chen
Mol Psychiatry advance online publication, January 29, 2008; doi:10.1038/sj.mp.4002135
A genome screen of 35 bipolar affective disorder pedigrees provides significant evidence for a susceptibility locus on chromosome 15q25-26
E Z McAuley, I P Blair, Z Liu, J M Fullerton, A Scimone, M Van Herten, M R Evans, K C Kirkby, J A Donald, P B Mitchell and P R Schofield
Mol Psychiatry advance online publication, January 29, 2008; doi:10.1038/sj.mp.4002146
January 15 2008
Original Articles
Association between the insulin-induced gene 2 (INSIG2) and weight gain in a German sample of antipsychotic-treated schizophrenic patients: perturbation of SREBP-controlled lipogenesis in drug-related metabolic adverse effects?
S Le Hellard, F M Theisen, M Haberhausen, M B Raeder, J Fernø, S Gebhardt, A Hinney, H Remschmidt, J C Krieg, C Mehler-Wex, M M Nöthen, J Hebebrand and V M Steen
Mol Psychiatry advance online publication, January 15, 2008; doi:10.1038/sj.mp.4002133
Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice
J C O'Connor, M A Lawson, C André, M Moreau, J Lestage, N Castanon, K W Kelley and R Dantzer
Mol Psychiatry advance online publication, January 15, 2008; doi:10.1038/sj.mp.4002148
Chronic stimulation of corticotropin-releasing factor receptor 1 enhances the anxiogenic response of the cholecystokinin system
T Sherrin, C Todorovic, T Zeyda, C H Tan, P W T Hon, Y-Z Zhu and J Spiess
Mol Psychiatry advance online publication, January 15, 2008; doi:10.1038/sj.mp.4002121
January 8 2008
Original Articles
To discard or not to discard: the neural basis of hoarding symptoms in obsessive-compulsive disorder
S K An, D Mataix-Cols, N S Lawrence, S Wooderson, V Giampietro, A Speckens, M J Brammer and M L Phillips
Mol Psychiatry advance online publication, January 8, 2008; doi:10.1038/sj.mp.4002129