Subject archive

Molecular Biology of Disease

2008

A systems biology approach to prediction of oncogenes and molecular perturbation targets in B-cell lymphomas

Kartik M Mani, Celine Lefebvre, Kai Wang, Wei Keat Lim, Katia Basso, Riccardo Dalla-Favera & Andrea Califano

doi:10.1038/msb.2008.2
Published online: 12 February 2008

Network-based global inference of human disease genes

Xuebing Wu, Rui Jiang, Michael Q Zhang & Shao Li

doi:10.1038/msb.2008.27
Published online: 06 May 2008

Metabolic profiling of the human response to a glucose challenge reveals distinct axes of insulin sensitivity

Oded Shaham, Ru Wei, Thomas J Wang, Catherine Ricciardi, Gregory D Lewis, Ramachandran S Vasan, Steven A Carr, Ravi Thadhani, Robert E Gerszten & Vamsi K Mootha

doi:10.1038/msb.2008.50
Published online: 05 August 2008

Finding multiple target optimal intervention in disease-related molecular network

Kun Yang, Hongjun Bai, Qi Ouyang, Luhua Lai & Chao Tang

doi:10.1038/msb.2008.60
Published online: 04 November 2008

p53-repressed miRNAs are involved with E2F in a feed-forward loop promoting proliferation

Ran Brosh, Reut Shalgi, Atar Liran, Gilad Landan, Katya Korotayev, Giang Huong Nguyen, Espen Enerly, Hilde Johnsen, Yosef Buganim, Hilla Solomon, Ido Goldstein, Shalom Madar, Naomi Goldfinger, Anne-Lise Børresen-Dale, Doron Ginsberg, Curtis C Harris, Yitzhak Pilpel, Moshe Oren & Varda Rotter

doi:10.1038/msb.2008.65
Published online: 25 November 2008

The liver pharmacological and xenobiotic gene response repertoire

Georges Natsoulis, Cecelia I Pearson, Jeremy Gollub, Barrett P Eynon, Joe Ferng, Ramesh Nair, Radha Idury, May D Lee, Mark R Fielden, Richard J Brennan, Alan H Roter & Kurt Jarnagin

doi:10.1038/msb.2008.9
Published online: 25 March 2008

1H NMR metabonomics approach to the disease continuum of diabetic complications and premature death

Ville-Petteri Mäkinen, Pasi Soininen, Carol Forsblom, Maija Parkkonen, Petri Ingman, Kimmo Kaski, Per-Henrik Groop & Mika Ala-Korpela for the FinnDiane Study Group

doi:10.1038/msb4100205
Published online: 12 February 2008

2007

Computational analysis of the synergy among multiple interacting genes

Dimitris Anastassiou

doi:10.1038/msb4100124
Published online: 13 February 2007

A network biology approach to prostate cancer

Ayla Ergün, Carolyn A Lawrence, Michael A Kohanski, Timothy A Brennan & James J Collins

doi:10.1038/msb4100125
Published online: 13 February 2007

Hubs in biological interaction networks exhibit low changes in expression in experimental asthma

Xin Lu, Vipul V Jain, Patricia W Finn & David L Perkins

doi:10.1038/msb4100138
Published online: 17 April 2007

A top-down systems biology view of microbiome-mammalian metabolic interactions in a mouse model

François-Pierre J Martin, Marc-Emmanuel Dumas, Yulan Wang, Cristina Legido-Quigley, Ivan K S Yap, Huiru Tang, Séverine Zirah, Gerard M Murphy, Olivier Cloarec, John C Lindon, Norbert Sprenger, Laurent B Fay, Sunil Kochhar, Peter van Bladeren, Elaine Holmes & Jeremy K Nicholson

doi:10.1038/msb4100153
Published online: 22 May 2007

Human disease classification in the postgenomic era: A complex systems approach to human pathobiology

Joseph Loscalzo, Isaac Kohane & Albert-Laszlo Barabasi

doi:10.1038/msb4100163
Published online: 10 July 2007

An integrated approach to prognosis using protein microarrays and nonparametric methods

Tanya Knickerbocker, Jiunn R Chen, Ravi Thadhani & Gavin MacBeath

doi:10.1038/msb4100167
Published online: 26 June 2007

Network-based classification of breast cancer metastasis

Han-Yu Chuang, Eunjung Lee, Yu-Tsueng Liu, Doheon Lee & Trey Ideker

doi:10.1038/msb4100180
Published online: 16 October 2007

A modular network model of aging

Huiling Xue, Bo Xian, Dong Dong, Kai Xia, Shanshan Zhu, Zhongnan Zhang, Lei Hou, Qingpeng Zhang, Yi Zhang & Jing-Dong J Han

doi:10.1038/msb4100189
Published online: 04 December 2007

Evolvable signaling networks of receptor tyrosine kinases: relevance of robustness to malignancy and to cancer therapy

Ido Amit, Ron Wides & Yosef Yarden

doi:10.1038/msb4100195
Published online: 04 December 2007

A map of human cancer signaling

Qinghua Cui, Yun Ma, Maria Jaramillo, Hamza Bari, Arif Awan, Song Yang, Simo Zhang, Lixue Liu, Meng Lu, Maureen O'Connor-McCourt, Enrico O Purisima & Edwin Wang

doi:10.1038/msb4100200
Published online: 18 December 2007

2006

Dynamic analysis of optimality in myocardial energy metabolism under normal and ischemic conditions

Ruo-Yu Luo, Sha Liao, Guan-Yang Tao, Yuan-Yuan Li, Shaoqun Zeng, Yi-Xue Li & Qingming Luo

doi:10.1038/msb4100071
Published online: 06 June 2006

Systems biology of SNPs

Neema Jamshidi & Bernhard Ø Palsson

doi:10.1038/msb4100077
Published online: 04 July 2006

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