A systems-level approach to mapping the telomere length maintenance gene circuitry
Rafi Shachar, Lior Ungar, Martin Kupiec, Eytan Ruppin & Roded Sharan
doi:10.1038/msb.2008.13
Published online:
04 March 2008
Subject archive
Signal Transduction
2008
Recurrent design patterns in the feedback regulation of the mammalian signalling network
Stefan Legewie, Hanspeter Herzel, Hans V Westerhoff & Nils Blüthgen
doi:10.1038/msb.2008.29
Published online:
06 May 2008
Understanding NF-
B signaling via mathematical modeling
Raymond Cheong, Alexander Hoffmann & Andre Levchenko
doi:10.1038/msb.2008.30
Published online:
06 May 2008
Fus3-triggered Tec1 degradation modulates mating transcriptional output during the pheromone response
Song Chou, Su Zhao, You Song, Haoping Liu & Qing Nie
doi:10.1038/msb.2008.47
Published online:
05 August 2008
Variable sizes of Escherichia coli chemoreceptor signaling teams
Robert G Endres, Olga Oleksiuk, Clinton H Hansen, Yigal Meir, Victor Sourjik & Ned S Wingreen
doi:10.1038/msb.2008.49
Published online:
05 August 2008
Synopsis | Full Text | PDF (1,892K) | Supplementary information
A quantitative comparison of sRNA-based and protein-based gene regulation
Pankaj Mehta, Sidhartha Goyal & Ned S Wingreen
doi:10.1038/msb.2008.58
Published online:
14 October 2008
Synopsis | Full Text | PDF (372K) | Supplementary information
Analysis of pairwise cell interactions using an integrated dielectrophoretic-microfluidic system
Zhizhong Yin, David Noren, C Joanne Wang, Rob Hang & Andre Levchenko
doi:10.1038/msb.2008.69
Published online:
16 December 2008
Synopsis | Full Text | PDF (4,541K) | Supplementary information
Robust and sensitive control of a quorum-sensing circuit by two interlocked feedback loops
Joshua W Williams, Xiaohui Cui, Andre Levchenko & Ann M Stevens
doi:10.1038/msb.2008.70
Published online:
16 December 2008
Synopsis | Full Text | PDF (400K) | Supplementary information
Linear combinations of docking affinities explain quantitative differences in RTK signaling
Andrew Gordus, Jordan A Krall, Elsa M Beyer, Alexis Kaushansky, Alejandro Wolf-Yadlin, Mark Sevecka, Bryan H Chang, John Rush & Gavin MacBeath
doi:10.1038/msb.2008.72
Published online:
16 December 2008
Synopsis | Full Text | PDF (3,153K) | Supplementary information
2007
A homeostatic model of IB metabolism to control constitutive NF-B activity
Ellen L O'Dea, Derren Barken, Raechel Q Peralta, Kim T Tran, Shannon L Werner, Jeffrey D Kearns, Andre Levchenko & Alexander Hoffmann
doi:10.1038/msb4100148
Published online:
08 May 2007
Environmental signal integration by a modular AND gate
J Christopher Anderson, Christopher A Voigt & Adam P Arkin
doi:10.1038/msb4100173
Published online:
14 August 2007
Synopsis | Full Text | PDF (226K) | Supplementary information
PhosphoPep—a phosphoproteome resource for systems biology research in Drosophila Kc167 cells
Bernd Bodenmiller, Johan Malmstrom, Bertran Gerrits, David Campbell, Henry Lam, Alexander Schmidt, Oliver Rinner, Lukas N Mueller, Paul T Shannon, Patrick G Pedrioli, Christian Panse, Hoo-Keun Lee, Ralph Schlapbach & Ruedi Aebersold
doi:10.1038/msb4100182
Published online:
16 October 2007
Ligand-dependent responses of the ErbB signaling network: experimental and modeling analyses
Marc R Birtwistle, Mariko Hatakeyama, Noriko Yumoto, Babatunde A Ogunnaike, Jan B Hoek & Boris N Kholodenko
doi:10.1038/msb4100188
Published online:
13 November 2007
Synopsis | Full Text | PDF (646K) | Supplementary information
Evolvable signaling networks of receptor tyrosine kinases: relevance of robustness to malignancy and to cancer therapy
Ido Amit, Ron Wides & Yosef Yarden
doi:10.1038/msb4100195
Published online:
04 December 2007
Capturing cell-fate decisions from the molecular signatures of a receptor-dependent signaling response
Dhiraj Kumar, Ravichandran Srikanth, Helena Ahlfors, Riitta Lahesmaa & Kanury V S Rao
doi:10.1038/msb4100197
Published online:
04 December 2007
Synopsis | Full Text | PDF (909K) | Supplementary information
2006
The proteomes of neurotransmitter receptor complexes form modular networks with distributed functionality underlying plasticity and behaviour
Andrew J Pocklington, Mark Cumiskey, J Douglas Armstrong & Seth G N Grant
doi:10.1038/msb4100041
Published online:
17 January 2006
Synopsis | Full Text | PDF (496K) | Supplementary information
A comprehensive map of the toll-like receptor signaling network
Kanae Oda & Hiroaki Kitano
doi:10.1038/msb4100057
Published online:
18 April 2006
Principles of microRNA regulation of a human cellular signaling network
Qinghua Cui, Zhenbao Yu, Enrico O Purisima & Edwin Wang
doi:10.1038/msb4100089
Published online:
12 September 2006
Effects of HER2 overexpression on cell signaling networks governing proliferation and migration
Alejandro Wolf-Yadlin, Neil Kumar, Yi Zhang, Sampsa Hautaniemi, Muhammad Zaman, Hyung-Do Kim, Viara Grantcharova, Douglas A Lauffenburger & Forest M White
doi:10.1038/msb4100094
Published online:
03 October 2006
Synopsis | Full Text | PDF (552K) | Supplementary information
Imaging single molecules in living cells for systems biology
Yasushi Sako
doi:10.1038/msb4100100
Published online:
17 October 2006
Long-range signaling by phosphoprotein waves arising from bistability in protein kinase cascades
Nick I Markevich, Mikhail A Tsyganov, Jan B Hoek & Boris N Kholodenko
doi:10.1038/msb4100108
Published online:
14 November 2006
2005
Phosphotyrosine interactome of the ErbB-receptor kinase family
Waltraud X Schulze, Lei Deng & Matthias Mann
doi:10.1038/msb4100012
Published online:
25 May 2005
Synopsis | Full Text | PDF (445K) | Supplementary information
A comprehensive pathway map of epidermal growth factor receptor signaling
Kanae Oda, Yukiko Matsuoka, Akira Funahashi & Hiroaki Kitano
doi:10.1038/msb4100014
Published online:
25 May 2005
A theoretical framework for specificity in cell signaling
Natalia L Komarova, Xiufen Zou, Qing Nie & Lee Bardwell
doi:10.1038/msb4100031
Published online:
18 October 2005
Threshold responses to morphogen gradients by zero-order ultrasensitivity
Gustavo J Melen, Sagi Levy, Naama Barkai & Ben-Zion Shilo
doi:10.1038/msb4100036
Published online:
13 December 2005
Synopsis | Full Text | PDF (461K) | Supplementary information
