The metabolic network model of arachidonic acid in human endothelial cell. This model is according to the paper: Finding Multiple-Target Optimal Intervention in Disease Related Molecular Network. Figure S3C in the paper can be reproduced by SBML ode solver.

 2008-09-08T15:24:29 2008-09-08T15:24:29 KPLAe x17 linEC 1 x4 KI12HPETEplae x2 KI15HPETEplae x15 KIPGF2plae linEC kPLAe 1 x1 ksEC iPLA kiPLA K15LOXe x18 x1 1 0 x1 k15LOXe 1 x2 ksEC K12LOXe con12LOXe x1 1 0 x1 k12LOXe 1 x4 ksEC KCOXe conCOXe x1 1 0 x1 kCOXe 1 x14 kiPGEcoxe x6 ksEC iCOX2 kiCOX2 K15LOXe x18 x1 1 0 x1 k15LOXe 1 x2 ksEC KPHGPxe conPHGPxe x2 1 0 x2 kPHGPxe 1 x3 ksEC kd15HPETEe x2 KPHGPxe conPHGPxe x2 1 0 x2 kPHGPxe 1 x3 ksEC kd15HETEe x3 K12LOXe con12LOXe x1 1 0 x1 k12LOXe 1 x4 ksEC KPHGPxe conPHGPxe x4 1 0 x4 kPHGPxe 1 x5 ksEC KPHGPxe conPHGPxe x4 1 0 x4 kPHGPxe 1 x5 ksEC kd12HETEe x5 KCOXe conCOXe x1 1 0 x1 kCOXe 1 x14 kiPGEcoxe x6 ksEC iCOX2 kiCOX2 KTXASe x19 x6 1 0 x6 kTXASe 1 x7 ksEC KPGISe conPGISe x6 1 0 x6 kPGISe 1 x2 ki15HPETEpgise x9 ksEC KPGDSe conPGDSe x6 1 0 x6 kPGDSe 1 x11 ksEC KPGESe x20 x6 1 0 x6 kPGESe 1 x1 kiAApgese x3 ki15HETEpgese x14 ksEC iPGES kiPGES kdPGHe x6 KTXASe x19 x6 1 0 x6 kTXASe 1 x7 ksEC kdTXAe x7 kdTXAe x7 kdTXBe x8 KPGISe conPGISe x6 1 0 x6 kPGISe 1 x2 ki15HPETEpgise x9 ksEC kdPGIe x9 kdPGIe x9 kdPGF1e x10 KPGDSe conPGDSe x6 1 0 x6 kPGDSe 1 x11 ksEC KPGFSe conPGFSe x11 1 0 x11 kPGFSe 1 0 kdPGDe x11 kdPGDe x11 kdPGJe x12 kdPGJe x12 KPGESe x20 x6 1 0 x6 kPGESe 1 x1 kiAApgese x3 ki15HETEpgese x14 ksEC iPGES kiPGES KCRe conCRe x14 1 0 x14 kCRe 1 x15 ksEC KKPRe conKPRe x14 1 0 x14 kKPRe 1 x15 ksEC KCRe conCRe x14 1 0 x14 kCRe 1 x15 ksEC KKPRe conKPRe x14 1 0 x14 kKPRe 1 x15 ksEC kdPGHe x6 KPGDHe conPGDHe x15 1 0 x15 kPGDHe 1 x16 ksEC KPGDHe conPGDHe x15 1 0 x15 kPGDHe 1 x16 ksEC kidPGJplae x13 x17 aPGE15loxe x14 x14 x14 x14 KIPGE15loxe KIPGE15loxe kd15LOXe x18 ki15HPETEtxase x2 kiPGHtxase x6 x19 kidPGJpgese x13 x20