TABLE 1 

FROM:

Top-down systems biology integration of conditional prebiotic modulated transgenomic interactions in a humanized microbiome mouse model

Francois-Pierre J Martin, Yulan Wang, Norbert Sprenger, Ivan K S Yap, Serge Rezzi, Ziad Ramadan, Emma Peré-Trepat, Florence Rochat, Christine Cherbut, Peter van Bladeren, Laurent B Fay, Sunil Kochhar, John C Lindon, Elaine Holmes & Jeremy K Nicholson

doi:10.1038/msb.2008.40

Table 1: Microbial species counts in mouse fecal and jejunal contents

Groups/log10 CFU	HBM (n=10)	HBM+ L. paracasei (n=9)	HBM+ L. paracasei +Pre1 (n=9)	HBM+ L. paracasei+ Pre2 (n=9)	HBM+ L. rhamnosus (n=9)	HBM+ L. rhamnosus +Pre1 (n=10)	HBM+ L. rhamnosus +Pre2 (n=9)
Key: Log10 CFU (colony forming unit) given per gram of wet weight of feces or wet weight of jejunal content. Data are presented as means.d. The average values obtained from the HBM+probiotics mice supplemented with prebiotics were compared with corresponding HBM+probiotics control mice, *, ** and *** designate significant difference at 95, 99 and 99.9% confidence level, respectively; —, probiotics not present in the gut microbiota.
Feses
L. paracasei	—	8.50.2	8.30.3*	8.10.4**	—	—	—
L. rhamnosus	—	—	—	—	7.80.2	7.60.4	7.90.3
E. coli	9.20.3	9.40.3	9.70.3	9.30.2	9.80.5	9.30.2*	9.30.2*
B. breve	9.10.2	7.782.13	8.51.5	8.71.5	8.70.3	9.80.3**	10.00.4***
B. longum	8.20.6	5.61.9	6.21.6	6.71.8	6.30.5	7.71.2**	9.31.04***
S. aureus	7.40.3	6.30.3	6.30.5	6.10.7	6.60.5	6.10.4	6.40.9
S. epidermidis	4.80.4	4.91.2	4.50.9	3.80.4	4.00.5	3.70.7	6.01.5
C. perfringens	7.20.3	7.00.5	6.51.0	5.90.6**	5.71.0	6.61.1	<5.0
Bacteroides distasonis	10.30.2	10.40.2	10.10.6	10.10.4	10.10.4	10.20.3	10.30.3
Jejunum
L. paracasei	—	4.21.8	2.90.8	2.60.9*	—	—	—
L. rhamnosus	—	—	—	—	3.61.3	3.11.3	3.00.8
E. coli	3.31.3	5.11.9	4.00.8	3.71.2	5.21.9	4.21.3	4.40.8
B. breve	2.71.4	2.51.0	2.71.3	3.01.4	2.40.8	4.01.6**	4.00.9**
B. longum	<2.0	<2.0	<2.0	<2.0	<2.0	<2.0	<2.0
S. aureus	4.10.9	3.81.3	4.10.9	3.70.7	4.20.7	3.01.3*	4.00.5
S. epidermidis	<3.0	<3.0	<3.0	<3.0	<3.0	<3.0	<3.0
C. perfringens	3.41.1	4.51.2	3.40.7	2.91.1	4.71.3	3.41.0*	3.20.5*
Bacteroides distasonis	3.41.6	4.81.6	3.21.2*	3.30.9*	3.81.7	4.01.3	4.11.3