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Intergenerational trauma, passed down through generations, is a significant concern for refugees and their descendants. Millions of people are forcibly displaced worldwide, with profound effects on mental and physical health. Refugees face many challenges, from acculturation to legal uncertainties, leading to a range of emotional struggles.
Deciding between treatments in depression relies on trial-and-error following the stepped-care approach (escalating to more intensive treatments after treatment failures). Recent research is focused on biomarkers and precision psychiatry; however, we argue that stratified psychiatry could be a practical alternative for individuals with mental health disorders.
Early evidence suggests psychedelics could help alleviate end-of-life anxiety and depression. Yet there has been little study or discussion of their integration into hospice and palliative care settings, where patients often have complex comorbidities and medication regimens. The authors discuss relevant clinical challenges and approaches.
This Comment proposes to increase knowledge of the effects of urbanicity on brain and mental health by linking existing human spatial data with macroenvironmental and regional socioeconomic data. It introduces hypothesis-free models to capture the data and model life in the city and suggests refinements for future studies into conditions that will soon affect the majority of the earth’s population.
This Comment highlights the intertwined nature of mental and brain health and disease. Common genetic, environmental and lifestyle factors contribute to psychiatric and neurological disorders, which partially share neurocognitive and pathophysiological mechanisms. A call for a more dimensional, interdisciplinary approach can accelerate the development of robust approaches to research, prevention and intervention.
Utilizing an everyday citizenship approach in forensic psychiatric care, by recognizing the agentive actions and relational interactions in mundane activities and caregiving communications, could substantially enhance and advance care practices.
Men often experience mental health issues in silence. This Comment considers the many manifestations of silence in men’s mental illness, which serve to reduce subjective wellbeing and social/occupational functioning amid elevating suicide risk.
Cases of mild or transient distress in young people are increasingly viewed as problems that require medical intervention. As CAMHS clinicians, we argue that this overmedicalization undermines the value of social support within the family and community, and funding cuts to nonmedical support services have only compounded the problem.
LGBTQIA+ older adults are under-represented in Alzheimer’s disease and mental health research. Here we highlight the current research evidence, social and policy influences, and ways healthcare and research professionals can improve equity in research and healthcare.
Climate change and ecological emergencies threaten life on Earth. This creates a distress that is in danger of being pathologized and dismissed. We examine how such feelings are rational and underpinned by instinctive compassion for the environment and each other. We must respond by supporting people to act with their full potential, amidst systemic and government failures.
Sex and gender play an important role in mental health. Clinical and preclinical research for novel treatments need to take this serious matter under consideration. The development of safe and effective treatments for specific populations can be achieved only with enhanced and targeted funding that will generate robust and reliable data.
Climate change is affecting mental health in all communities, especially in young people. It is critical that we consider how to support young people affected by climate change anxiety and the possibilities of looking forward to supporting them.
In this Comment, Patwary et al. discuss the mental health needs of the Turkey–Syria earthquake survivors from an internal point of view, providing suggestions on what could be done for short- and long-term mental health improvement.
The mental health implications of the 2023 Turkey–Syria earthquake will probably be profound. Here we present research from prior disasters related to the potential negative mental health effects of the earthquake and its aftermath and provide suggestions for mitigating potential deleterious consequences.
A new survey from the International Alliance of Mental Health Research Funders explores how funders collaborate with people with lived experience of mental health challenges, and reveals potential routes to improve involvement.
Socioeconomic inequalities are antecedents for poor mental health outcomes. Mental illness is highly prevalent internationally — impacting 1 in 8 people, with incidence of anxiety and depression skyrocketing during the pandemic. In the USA, one of the world’s wealthiest nations, the economic outlook remains bleak.
Moving the needle in mental health research requires doing justice to the social, psychological, biological and developmental complexities that affect people in their living environments. We developed a comprehensive national research program to achieve scale and depth through translational project bundles focused on early recognition and prevention, urban mental health, and enhanced psychotherapy, underpinned by a range of shared infrastructures. The program was consistently co-created with and will involve people with lived experience at all stages of research.
Adolescents differ in their beliefs, or mindsets, about the nature and workings of their personal qualities. Here we present theory and data that show why changing adolescents’ mindsets can lead to more productive coping with challenging situations and improved mental health.
Neurotechnologies that measure and modulate brain activity have not yet reached widespread clinical relevance. To accelerate translation into patient care, we propose three strategic adjustments in neurotechnology research — to consider the scope, scalability and stakeholders.
