Naturejobs

Converging on DNA p3

Paul Smaglik

doi:10.1038/nj6917-03a

Full Text | PDF (68K)

Opinion

Trust and how to sustain it p719

Against a background of declining public trust in traditional institutions, scientists must work to retain their high public-confidence ratings. There are warnings and lessons to be learned from the events of 2002.

doi:10.1038/420719a

Full Text | PDF (39K)

Managing CERN's industries p719

Europe's huge particle-physics laboratory is now in need of both brilliant science and outstanding management.

doi:10.1038/420719b

Full Text | PDF (39K)

News

Stanford announces private plan to get stem-cell research moving p721

Erika Check

doi:10.1038/420721a

Full Text | PDF (80K)

CERN collider project back on track p721

Alison Abbott

doi:10.1038/420721b

Full Text | PDF (80K)

Ocean tests raise doubts over use of algae as carbon sink p722

Rex Dalton

doi:10.1038/420722a

Full Text | PDF (127K)

Mass resignation forces Italian rethink on university funds p722

Alison Abbott

doi:10.1038/420722b

Full Text | PDF (127K)

ESA weighs up future after Ariane explosion p723

David Adam

doi:10.1038/420723a

Full Text | PDF (46K)

Australian bushfire centre rises from the flames p723

Carina Dennis

doi:10.1038/420723b

Full Text | PDF (46K)

Neutrino projects are poles apart, says panel p724

Geoff Brumfiel

doi:10.1038/420724a

Full Text | PDF (75K)

Corporate chiefs told to follow animal urges p724

John Whitfield

doi:10.1038/420724b

Full Text | PDF (75K)

news in brief p726

doi:10.1038/420726a

Full Text | PDF (87K)

2002 in context

Misconduct: The stars who fell to Earth p728

Controversy has been the watchword in a year dogged by dispute. Misconduct revelations, clashes over transgenic crops, and confusion over stem cells have threatened to overshadow triumphs in fields from palaeoanthropology to fundamental physics. Nature's reporters recount the year's talking points.

Rex Dalton

doi:10.1038/420728a

Full Text | PDF (284K)

Genomics: Sorry, dogs — man's got a new best friend p729

Alison Abbott

doi:10.1038/420729a

Full Text | PDF (137K)

Agribiotech: More heat than light p730

Peter Aldhous

doi:10.1038/420730a

Full Text | PDF (308K)

Cosmology: It all adds up p731

Geoff Brumfiel

doi:10.1038/420731a

Full Text | PDF (307K)

Antihydrogen: Holding up a mirror to physics' world view p731

Geoff Brumfiel

doi:10.1038/420731b

Full Text | PDF (307K)

Small RNAs: The genome's guiding hand? p732

Carina Dennis

doi:10.1038/420732a

Full Text | PDF (161K)

Sustainable development: Now we're talking p733

Tom Clarke

doi:10.1038/420733a

Full Text | PDF (173K)

Stem cells: Articles of faith adulterated p734

Helen Pearson

doi:10.1038/420734a

Full Text | PDF (145K)

Palaeoanthropology: Face to face with our past p735

Rex Dalton

doi:10.1038/420735a

Full Text | PDF (167K)

Gene therapy: Shining hopes dented — but not dashed p735

Erika Check

doi:10.1038/420735b

Full Text | PDF (167K)

Biodefence: Ploughshares into swords p736

Erika Check

doi:10.1038/420736a

Full Text | PDF (102K)

Attosecond science: The fast show p737

Jim Giles

doi:10.1038/420737a

Full Text | PDF (109K)

Neutrino physics: Tanked up and ready for action p737

David Cyranoski

doi:10.1038/420737b

Full Text | PDF (109K)

Correspondence

Biometrics was no match for hair-raising tricks p739

People have been fooling the latest thing in security for a very long time.

Michael M. Bronstein and Alexander M. Bronstein

doi:10.1038/420739a

Full Text | PDF (46K)

Scientific misconduct: the state's role has limits p739

David Korn

doi:10.1038/420739b

Full Text | PDF (46K)

Scientific misconduct: ORI survey is flawed p739

Steven L. Teitelbaum

doi:10.1038/420739c

Full Text | PDF (46K)

Sounding the alarm on underwater noise p740

Michael Stocker

doi:10.1038/420740a

Full Text | PDF (35K)

Why astronomy is the star of the news show p740

Howard A. Smith

doi:10.1038/420740b

Full Text | PDF (35K)

Book Reviews

Baby love p741

Cruel experiments on monkeys showed that infants need affection.

Alison Jolly reviews Love at Goon Park: Harry Harlow and the Science of Affection by Deborah Blum

doi:10.1038/420741a

Full Text | PDF (184K)

Immunology tomorrow p741

Franziska Michor and Martin A. Nowak review Immunology and Evolution of Infectious Disease by Steven A. Frank

doi:10.1038/420741b

Full Text | PDF (184K)

A drink to your health! p742

John Mowbray reviews Wine: A Scientific Exploration edited by Merton Sandler and Roger Pinder

doi:10.1038/420742a

Full Text | PDF (246K)

London calling p743

Paul M. Grant reviews A Thread Across the Ocean by John Steele Gordon

doi:10.1038/420743a

Full Text | PDF (317K)

Science in culture p744

Martin Kemp reviews

doi:10.1038/420744a

Full Text | PDF (207K)

concepts

Multicellularity: Evolution and the egg p745

Lewis Wolpert and Eörs Szathmáry

doi:10.1038/420745a

Full Text | PDF (85K)

News and Views

Cosmology: Background comes to the fore p747

The cosmic microwave background radiation is a unique source of information about the early Universe. The detection of its polarization could lead to confirmation of an inflationary phase soon after the Big Bang.

Matias Zaldarriaga

doi:10.1038/420747a

Full Text | PDF (133K)

Immunology: Remembrance of things past p748

Memory T cells help us to fight off infectious microorganisms that we have encountered before. There are two models for the generation of memory cells, and new work provides support for one of them.

Michael J. Bevan

doi:10.1038/420748a

Full Text | PDF (72K)

Condensed-matter physics: Dense ice in detail p749

A substance as simple as water is in fact a rich source of interesting physics. The solid phase contains several amorphous forms of ice, including one with a very dense structure, the details of which have now been revealed.

Dennis D. Klug

doi:10.1038/420749a

Full Text | PDF (78K)

Neurobiology: How hardwired is the brain? p751

In a technological breakthrough, two groups have shown that it is possible to study the turnover of spines — tiny protrusions on nerve cells — in live mice. But it's still uncertain just how dynamic the spines are.

Ole P. Ottersen and P. Johannes Helm

doi:10.1038/420751a

Full Text | PDF (74K)

Applied physics: A light-emitting sandwich filling p752

Electroluminescence has taken a new turn with the combination of organic light-emitting diodes and inorganic quantum dots. The efficiency of light emission is much higher in the latest easy-to-make device.

Tetsuo Tsutsui

doi:10.1038/420752a

Full Text | PDF (143K)

Plant science: On the slide p753

Christopher Surridge

doi:10.1038/420753a

Full Text | PDF (82K)

Genomics: Return of a little squirt p755

The draft sequence of the genome of a dim and distant relation of vertebrates will allow closer inspection of vertebrate origins. Some people have been waiting more than a hundred years for this.

Henry Gee

doi:10.1038/420755a

Full Text | PDF (145K)

100 and 50 years ago p755

doi:10.1038/420755b

Full Text | PDF (145K)

Computational biology: Evolution plays dice p756

In computer simulations, initially identical populations of organisms growing in identical environments follow very different evolutionary trajectories. Mutational interdependence is a key factor.

Philip Gerrish

doi:10.1038/420756a

Full Text | PDF (113K)

Obituary: René Thom (1923–2002) p758

Ivar Ekeland

doi:10.1038/420758a

Full Text | PDF (110K)

Brief Communications

Organic chemistry: A digital fluorescent molecular photoswitch p759

The signal from a gaudy ring molecule flashes on and off as light flicks it open and shut.

Masahiro Irie, Tuyoshi Fukaminato, Takatoshi Sasaki, Naoto Tamai and Tsuyoshi Kawai

doi:10.1038/420759a

First paragraph | Full Text | PDF (128K) | Supplementary information

Palaeontology: First Devonian tetrapod from Asia p760

Min Zhu, Per E. Ahlberg, Wenjin Zhao and Liantao Jia

doi:10.1038/420760a

First paragraph | Full Text | PDF (142K)

Nanotechnology: Carbon nanotubes with DNA recognition p761

Keith A. Williams, Peter T. M. Veenhuizen, Beatriz G. de la Torre, Ramon Eritja and Cees Dekker

doi:10.1038/420761a

First paragraph | Full Text | PDF (83K)

Secure communication: Quantum cryptography with a photon turnstile p762

Edo Waks, Kyo Inoue, Charles Santori, David Fattal, Jelena Vuckovic, Glenn S. Solomon and Yoshihisa Yamamoto

doi:10.1038/420762a

First paragraph | Full Text | PDF (83K) | Supplementary information

Articles

Measurement of polarization with the Degree Angular Scale Interferometer p763

E. M. Leitch, J. M. Kovac, C. Pryke, J. E. Carlstrom, N. W. Halverson, W. L. Holzapfel, M. Dragovan, B. Reddall and E. S. Sandberg

doi:10.1038/nature01271

Abstract | Full Text | PDF (482K)

See also: News and Views by Zaldarriaga

Detection of polarization in the cosmic microwave background using DASI p772

J. M. Kovac, E. M. Leitch, C. Pryke, J. E. Carlstrom, N. W. Halverson and W. L. Holzapfel

doi:10.1038/nature01269

Abstract | Full Text | PDF (516K)

See also: News and Views by Zaldarriaga

Long-term in vivo imaging of experience-dependent synaptic plasticity in adult cortex p788

Joshua T. Trachtenberg, Brian E. Chen, Graham W. Knott, Guoping Feng, Joshua R. Sanes, Egbert Welker and Karel Svoboda

doi:10.1038/nature01273

Abstract | Full Text | PDF (602K) | Supplementary information

See also: News and Views by Ottersen & Helm

Letters to Nature

Direct detection of variable tropospheric clouds near Titan's south pole p795

Michael E. Brown, Antonin H. Bouchez and Caitlin A. Griffith

doi:10.1038/nature01302

First paragraph | Full Text | PDF (207K)

Charge-ordered ferromagnetic phase in La_0.5Ca_0.5MnO₃ p797

James C. Loudon, Neil D. Mathur and Paul A. Midgley

doi:10.1038/nature01299

First paragraph | Full Text | PDF (225K) | Supplementary information

Electroluminescence from single monolayers of nanocrystals in molecular organic devices p800

Seth Coe, Wing-Keung Woo, Moungi Bawendi and Vladimir Bulovi

doi:10.1038/nature01217

First paragraph | Full Text | PDF (315K)

See also: News and Views by Tsutsui

Metastable garnet in oceanic crust at the top of the lower mantle p803

Tomoaki Kubo, Eiji Ohtani, Tadashi Kondo, Takumi Kato, Motomasa Toma, Tomofumi Hosoya, Asami Sano, Takumi Kikegawa and Toshiro Nagase

doi:10.1038/nature01281

First paragraph | Full Text | PDF (263K)

SAR11 clade dominates ocean surface bacterioplankton communities p806

Robert M. Morris, Michael S. Rappé, Stephanie A. Connon, Kevin L. Vergin, William A. Siebold, Craig A. Carlson and Stephen J. Giovannoni

doi:10.1038/nature01240

First paragraph | Full Text | PDF (305K)

Macroevolution simulated with autonomously replicating computer programs p810

Gabriel Yedid and Graham Bell

doi:10.1038/nature01151

First paragraph | Full Text | PDF (215K)

See also: News and Views by Gerrish

Long-term dendritic spine stability in the adult cortex p812

Jaime Grutzendler, Narayanan Kasthuri and Wen-Biao Gan

doi:10.1038/nature01276

First paragraph | Full Text | PDF (283K) | Supplementary information

See also: News and Views by Ottersen & Helm

A role for casein kinase 2 in the Drosophila circadian clock p816

Jui-Ming Lin, Valerie L. Kilman, Kevin Keegan, Brie Paddock, Myai Emery-Le, Michael Rosbash and Ravi Allada

doi:10.1038/nature01235

First paragraph | Full Text | PDF (307K)

Glucose transporter recycling in response to insulin is facilitated by myosin Myo1c p821

Avirup Bose, Adilson Guilherme, Stacey I. Robida, Sarah M. C. Nicoloro, Qiong L. Zhou, Zhen Y. Jiang, Darcy P. Pomerleau and Michael P. Czech

doi:10.1038/nature01246

First paragraph | Full Text | PDF (419K) | Supplementary information

Helper T cells regulate type-2 innate immunity in vivo p825

Kanade Shinkai, Markus Mohrs and Richard M. Locksley

doi:10.1038/nature01202

First paragraph | Full Text | PDF (488K) | Supplementary information

Chloroplast avoidance movement reduces photodamage in plants p829

Masahiro Kasahara, Takatoshi Kagawa, Kazusato Oikawa, Noriyuki Suetsugu, Mitsue Miyao and Masamitsu Wada

doi:10.1038/nature01213

First paragraph | Full Text | PDF (296K)

Role for a Drosophila Myb-containing protein complex in site-specific DNA replication p833

Eileen L. Beall, J. Robert Manak, Sharleen Zhou, Maren Bell, Joseph S. Lipsick and Michael R. Botchan

doi:10.1038/nature01228

First paragraph | Full Text | PDF (428K) | Supplementary information

The RNA processing exosome is linked to elongating RNA polymerase II in Drosophila p837

Erik D. Andrulis, Janis Werner, Arpi Nazarian, Hediye Erdjument-Bromage, Paul Tempst and John T. Lis

doi:10.1038/nature01181

First paragraph | Full Text | PDF (369K)

A ribozyme composed of only two different nucleotides p841

John S. Reader and Gerald F. Joyce

doi:10.1038/nature01185

First paragraph | Full Text | PDF (175K)

insight

Inflammation p845

Ursula Weiss

doi:10.1038/nature01319

Full Text | PDF (102K)

Points of control in inflammation p846

Carl Nathan

doi:10.1038/nature01320

Abstract | Full Text | PDF (253K)

The inflammatory reflex p853

Kevin J. Tracey

doi:10.1038/nature01321

Abstract | Full Text | PDF (277K)

Inflammation and cancer p860

Lisa M. Coussens and Zena Werb

doi:10.1038/nature01322

Abstract | Full Text | PDF (561K)

Inflammation in atherosclerosis p868

Peter Libby

doi:10.1038/nature01323

Abstract | Full Text | PDF (348K)

Mast cells in autoimmune disease p875

Christophe Benoist and Diane Mathis

doi:10.1038/nature01324

Abstract | Full Text | PDF (249K)

Inflammation and therapeutic vaccination in CNS diseases p879

Howard L. Weiner and Dennis J. Selkoe

doi:10.1038/nature01325

Abstract | Full Text | PDF (236K)

The immunopathogenesis of sepsis p885

Jonathan Cohen

doi:10.1038/nature01326

Abstract | Full Text | PDF (1,775K)