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Nature 434, 443 (24 March 2005) | doi:10.1038/434443a; Published online 23 March 2005

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Genetics:  Hotheaded healer

Detlef Weigel1 & Gerd Jürgens2

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A previously unknown way of reversing genome-wide sequence changes in DNA has been revealed by an analysis of plants carrying mutations in a gene called HOTHEAD. The mechanism remains a mystery.

Variety is the spice of life. This adage applies as much to genetic material as to anything else — if DNA were static, there would be no change over time and no evolution.

  1. Detlef Weigel is in the Department of Molecular Biology, Max Planck Institute for Developmental Biology, D-72076 Tübingen, Germany.
    e-mail: Email: weigel@weigelworld.org
  2. Gerd Jürgens is at the Centre for Molecular Biology of Plants (ZMBP), University of Tübingen, D-72076 Tübingen, Germany.
    e-mail: Email: gerd.juergens@zmbp.uni-tuebingen.de

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