Editorials

Sustainable outcomes from Gleneagles p1137

African nations will be more likely to support development projects whose outcomes are indispensable to them. Participants at next week's G8 summit should focus aid in this direction.

doi: 10.1038/4351137a

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Bringing neuroscience to the classroom p1138

Is the US National Science Foundation jumping the gun with its plans for education?

doi: 10.1038/4351138a

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Crystal clear p1138

Clarifying the Nature journals' policy on data deposition for chemical structures.

doi: 10.1038/4351138b

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Research Highlights

Research highlights p1140

doi: 10.1038/4351140a

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News

Japan consoled with contracts as France snares fusion project p1142

International partners finally agree that next-generation reactor will be built in Europe.

Declan Butler

doi: 10.1038/4351142a

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Clear skies raise global-warming estimates p1142

Cleaner air could remove a vital brake on climate change.

Quirin Schiermeier

doi: 10.1038/4351142b

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Sidelines p1144

doi: 10.1038/4351144a

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Japan's university shake-up wins faint praise after first year p1144

Despite some benefits, few are convinced that research standards will rise.

Ichiko Fuyuno

doi: 10.1038/4351144b

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Shrinking budget grounds German space research p1145

Scientists fear specialized labs will founder if budget cuts continue.

Alison Abbott

doi: 10.1038/4351145a

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Science & Africa:  A message to the G8 summit p1146

Africa's scientists tell industrialized nations what they need to hear.

doi: 10.1038/4351146a

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News in brief p1150

doi: 10.1038/4351150a

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News Features

Energy:  China's burning ambition p1152

The economic miracle that is transforming the world's most populous nation is threatened by energy shortages and rising pollution. It also risks plunging the planet's climate into chaos. Peter Aldhous reports.

doi: 10.1038/4351152a

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See also: Editor's summary

Educational research:  Big plans for little brains p1156

Experts in neuroscience, computing and education are coming together in a massive effort to put the way in which children are taught on a sounder scientific footing. Trisha Gura profiles this ambitious — some might say foolhardy — initiative.

doi: 10.1038/4351156a

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Business

Array of possibilities opens up in genotyping p1159

Technology is no longer limiting the search for genetic diseases.

Virginia Gewin

doi: 10.1038/4351159a

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In brief p1159

doi: 10.1038/4351159b

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Correspondence

Promoting dialogue is the best way to combat ID in classrooms p1160

Herman L. Mays, Jr

doi: 10.1038/4351160a

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Science and religion can strengthen each other p1160

Philip C. Farese

doi: 10.1038/4351160b

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Thoughtful peer review is worth the time it takes p1160

Xavier Michalet

doi: 10.1038/4351160c

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Despite some flaws, online submission is the future p1160

Ying-Hen Hsieh

doi: 10.1038/4351160d

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Books and Arts

Expanding the Universe p1161

Just how many dimensions are there?

Paul Davies reviews Warped Passages: Unravelling the Universe's Hidden Dimensions by Lisa Randall

doi: 10.1038/4351161a

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Making small talk p1162

Fran Balkwill reviews The Language of Life: How Cells Communicate in Health and Disease by Debra Niehoff

doi: 10.1038/4351162a

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Exhibition:  Colour vision p1162

doi: 10.1038/4351162b

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Hitching a lift p1163

Gabor Lövei reviews Out of Eden: An Odyssey of Ecological Invasion by Alan Burdick

doi: 10.1038/4351163a

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Essay

Now you see it, now you don't p1165

Cell doctrine: modern biology and medicine see the cell as the fundamental building block of living organisms, but this concept breaks down at different perspectives and scales.

Neil D. Theise

doi: 10.1038/4351165a

Full Text | PDF (125K)

News and Views

Evolutionary biology:  Males from Mars p1167

In an ant species — or is it two species? — females are produced only by females and males only by males. Explanations of this revelation have to invoke some decidedly offbeat patterns of natural selection.

David Queller

doi: 10.1038/4351167a

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Fluid dynamics:  Impact on Everest p1168

When a drop of liquid plummets onto a surface, the result is a splash — but not it seems if the process occurs at reduced atmospheric pressure. Here, perhaps, is a way to tune splash behaviour for practical ends.

David Quéré

doi: 10.1038/4351168a

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Cancer biology:  Summing up cancer stem cells p1169

Are current cancer drugs targeted at the wrong kinds of cells? A pioneering approach to the development of treatments uses a mathematical model to follow how different types of tumour cells respond to therapy.

Brian J. P. Huntly and D. Gary Gilliland

doi: 10.1038/4351169a

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Geophysics:  Hot fluids and cold crusts p1171

Conventional wisdom says that changes to crustal rocks pushed down deep when continents collide develop over millions of years. But it seems that some metamorphism may be caused by tectonic events lasting only a decade.

Simon Kelley

doi: 10.1038/4351171a

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Biophysics:  Fashionable cells p1172

How can cells deform yet maintain optimal function? Probing the similarities in the properties of a cell's network of structural filaments, and those of soft glassy materials, may help in tackling this question.

Chun Y. Seow

doi: 10.1038/4351172a

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Cancer:  A changing global view p1172

Barbara Marte

doi: 10.1038/4351172b

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Imaging techniques:  Particular magnetic insights p1173

Over the past 30 years magnetic resonance imaging has been refined into a widely used technique. A method known as magnetic particle imaging has now been devised which offers an inner view from a different angle.

Andreas Trabesinger

doi: 10.1038/4351173a

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50 & 100 years ago p1174

doi: 10.1038/4351174a

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Gene regulation:  Expression and silencing coupled p1174

The RNA interference pathway can inhibit the expression of specific genes. It now seems that an essential component of the silencing process is the gene-expression machinery itself.

Stephen Buratowski and Danesh Moazed

doi: 10.1038/4351174b

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Obituary:  Keiiti Aki (1930−2005) p1176

Seismologist extraordinaire.

Paul G. Richards

doi: 10.1038/4351176a

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Brief Communications

Animal behaviour:  Continuous activity in cetaceans after birth p1177

The exceptional wakefulness of newborn whales and dolphins has no ill-effect on their development.

Oleg Lyamin, Julia Pryaslova, Valentine Lance and Jerome Siegel

doi: 10.1038/4351177a

First paragraph | Full Text | PDF (138K) | Supplementary information

Feature

China's environment in a globalizing world p1179

How China and the rest of the world affect each other.

Jianguo Liu and Jared Diamond

doi: 10.1038/4351179a

Full Text | PDF (561K) | Supplementary information

See also: Editor's summary

Progress

Strong present-day aerosol cooling implies a hot future p1187

Meinrat O. Andreae, Chris D. Jones and Peter M. Cox

doi: 10.1038/nature03671

Abstract | Full Text | PDF (226K)

Articles

Short-lived orogenic cycles and the eclogitization of cold crust by spasmodic hot fluids p1191

Alfredo Camacho, James K. W. Lee, Bastiaan J. Hensen and Jean Braun

doi: 10.1038/nature03643

Abstract | Full Text | PDF (429K) | Supplementary information

See also: Editor's summary | News and Views by Kelley

Structure of a Na⁺/H⁺ antiporter and insights into mechanism of action and regulation by pH p1197

Carola Hunte, Emanuela Screpanti, Miro Venturi, Abraham Rimon, Etana Padan and Hartmut Michel

doi: 10.1038/nature03692

Abstract | Full Text | PDF (447K) | Supplementary information

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Letters

The U/Th production ratio and the age of the Milky Way from meteorites and Galactic halo stars p1203

Nicolas Dauphas

doi: 10.1038/nature03645

First paragraph | Full Text | PDF (183K) | Supplementary information

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Neutron and X-ray diffraction study of the broken symmetry phase transition in solid deuterium p1206

Igor Goncharenko and Paul Loubeyre

doi: 10.1038/nature03699

First paragraph | Full Text | PDF (289K)

Soft X-ray microscopy at a spatial resolution better than 15 nm p1210

Weilun Chao, Bruce D. Harteneck, J. Alexander Liddle, Erik H. Anderson and David T. Attwood

doi: 10.1038/nature03719

First paragraph | Full Text | PDF (293K)

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Tomographic imaging using the nonlinear response of magnetic particles p1214

Bernhard Gleich and Jürgen Weizenecker

doi: 10.1038/nature03808

First paragraph | Full Text | PDF (278K)

See also: Editor's summary | News and Views by Trabesinger

Remobilization of southern African desert dune systems by twenty-first century global warming p1218

David S. G. Thomas, Melanie Knight and Giles F. S. Wiggs

doi: 10.1038/nature03717

First paragraph | Full Text | PDF (512K) | Supplementary information

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Imaging the Indian subcontinent beneath the Himalaya p1222

Vera Schulte-Pelkum, Gaspar Monsalve, Anne Sheehan, M. R. Pandey, Som Sapkota, Roger Bilham and Francis Wu

doi: 10.1038/nature03678

First paragraph | Full Text | PDF (575K) | Supplementary information

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Experimental demonstration of chaos in a microbial food web p1226

Lutz Becks, Frank M. Hilker, Horst Malchow, Klaus Jürgens and Hartmut Arndt

doi: 10.1038/nature03627

First paragraph | Full Text | PDF (315K) | Supplementary information

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Clonal reproduction by males and females in the little fire ant p1230

Denis Fournier, Arnaud Estoup, Jérôme Orivel, Julien Foucaud, Hervé Jourdan, Julien Le Breton and Laurent Keller

doi: 10.1038/nature03705

First paragraph | Full Text | PDF (284K)

See also: Editor's summary | News and Views by Queller

Orofacial somatomotor responses in the macaque monkey homologue of Broca's area p1235

Michael Petrides, Geneviève Cadoret and Scott Mackey

doi: 10.1038/nature03628

First paragraph | Full Text | PDF (240K) | Supplementary information

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Phosphoinositide phosphatase activity coupled to an intrinsic voltage sensor p1239

Yoshimichi Murata, Hirohide Iwasaki, Mari Sasaki, Kazuo Inaba and Yasushi Okamura

doi: 10.1038/nature03650

First paragraph | Full Text | PDF (392K) | Supplementary information

Ephrin signalling controls brain size by regulating apoptosis of neural progenitors p1244

Vanessa Depaepe, Nathalie Suarez-Gonzalez, Audrey Dufour, Lara Passante, Jessica A Gorski, Kevin R. Jones, Catherine Ledent and Pierre Vanderhaeghen

doi: 10.1038/nature03651

First paragraph | Full Text | PDF (576K) | Supplementary information

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Auxin inhibits endocytosis and promotes its own efflux from cells p1251

Tomasz Paciorek, Eva Zaímalová, Nadia Ruthardt, Jan Petráek, York-Dieter Stierhof, Jürgen Kleine-Vehn, David A. Morris, Neil Emans, Gerd Jürgens, Niko Geldner and Jií Friml

doi: 10.1038/nature03633

First paragraph | Full Text | PDF (528K) | Supplementary information

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The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae p1257

Thimo Kurz, Nurhan Özlü, Fabian Rudolf, Sean M. O'Rourke, Brian Luke, Kay Hofmann, Anthony A. Hyman, Bruce Bowerman and Matthias Peter

doi: 10.1038/nature03662

First paragraph | Full Text | PDF (466K) | Supplementary information

Global histone modification patterns predict risk of prostate cancer recurrence p1262

David B. Seligson, Steve Horvath, Tao Shi, Hong Yu, Sheila Tze, Michael Grunstein and Siavash K. Kurdistani

doi: 10.1038/nature03672

First paragraph | Full Text | PDF (356K) | Supplementary information

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Dynamics of chronic myeloid leukaemia p1267

Franziska Michor, Timothy P. Hughes, Yoh Iwasa, Susan Branford, Neil P. Shah, Charles L. Sawyers and Martin A. Nowak

doi: 10.1038/nature03669

First paragraph | Full Text | PDF (319K) | Supplementary information

See also: Editor's summary | News and Views by Huntly & Gilliland

Escherichia coli swim on the right-hand side p1271

Willow R. DiLuzio, Linda Turner, Michael Mayer, Piotr Garstecki, Douglas B. Weibel, Howard C. Berg and George M. Whitesides

doi: 10.1038/nature03660

First paragraph | Full Text | PDF (224K) | Supplementary information

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RNA-interference-directed chromatin modification coupled to RNA polymerase II transcription p1275

Vera Schramke, Daniel M. Sheedy, Ahmet M. Denli, Carolina Bonila, Karl Ekwall, Gregory J. Hannon and Robin C. Allshire

doi: 10.1038/nature03652

First paragraph | Full Text | PDF (685K) | Supplementary information

See also: News and Views by Buratowski & Moazed

Erratum: Large Cretaceous sphenodontian from Patagonia provides insight into lepidosaur evolution in Gondwana p1280

Sebastián Apesteguía and Fernando E. Novas

doi: 10.1038/nature03878

Full Text | PDF (62K)

Corrigendum: Mg isotope evidence for contemporaneous formation of chondrules and refractory inclusions p1280

Martin Bizzarro, Joel A. Baker and Henning Haack

doi: 10.1038/nature03919

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Naturejobs

Take your partner by the hand... p1281

Analysing company partners is key to succeeding in shifting biotech landscape

Paul Smaglik

doi: 10.1038/nj7046-1281a

Full Text | PDF (119K)

Immunology goes global p1282

Scientists seeking immunology posts are looking beyond the United States and scattering all over the globe. They are re-evaluating both the focus of their work and where they choose to pursue it, says Myrna Watanabe.

Myrna Watanabe

doi: 10.1038/nj7046-1282a

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Futures

Are we not men? p1286

Meet the family...

Henry Gee

doi: 10.1038/4351286a

Full Text | PDF (311K)