Access
To read this story in full you will need to login or make a payment (see right).
Insight
Nature 438, 937-945 (15 December 2005) | doi:10.1038/nature04479; Published online 14 December 2005
Open Innovation Challenges
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
-
Direct Molecular Detection of Proteins and Nucleic Acids
This Challenge is looking for novel approaches to protein and nucleic acid detection. This is an Id...
- More Challenges
- Powered by:
nature jobs
Post Doctoral Research Assistant
- University of Bedfordshire
- Bedford, UK
Senior Lecturer / Lecturer in Filarial Parasitology
- LSTM
- Liverpool, United Kingdom
Review Article Endothelial cells and VEGF in vascular development
Leigh Coultas1, Kallayanee Chawengsaksophak1 & Janet Rossant1
Abstract
The intricate patterning processes that establish the complex vascular system during development depend on a combination of intrinsic pre-patterning and extrinsic responses to environmental parameters. Mutational studies in mice and fish have shown that the vascular system is highly sensitive to genetic disruption and have identified potential targets for therapeutic interventions. New insights into non-vascular roles of vascular endothelial growth factor and the requirement for endothelial cells in adult organs and stem-cell niches highlight possible side effects of anti-angiogenic therapy and the need for new targets.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Splitting vessels: Keeping lymph apart from bloodNature Medicine News and Views (01 Feb 2003)
