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Nature 440, 284-285 (16 March 2006) | doi:10.1038/440284a; Published online 15 March 2006
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Alzheimer's disease: A needle from the haystack
Richard Morris1 & Lennart Mucke2
Abstract
Abnormal protein clumps of many varieties build up in the brains of individuals with Alzheimer's disease. But which types actually cause memory deficits? The behaviour of model mice might help to find out.
A huge array of neurodegenerative diseases seems to be caused by abnormal clusters of certain proteins. Many of these disorders are on the rise and cannot be treated effectively, including the most frequent among them — Alzheimer's disease1.
- Richard Morris is in the Laboratory for Cognitive Neuroscience, College of Medicine and Veterinary Medicine, University of Edinburgh, 1 George Square, Edinburgh EH8 9JZ, UK.
Email: r.g.m.morris@ed.ac.uk - Lennart Mucke is at the Gladstone Institute of Neurological Disease and the University of California, San Francisco, 1650 Owens Street, San Francisco, California 94158, USA.
Email: lmucke@gladstone.ucsf.edu
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