Access
To read this story in full you will need to login or make a payment (see right).
Insight
Nature 441, 431-436 (25 May 2006) | doi:10.1038/nature04870; Published online 24 May 2006
Open Innovation Challenges
-
Fast Growth of Transformed Soybean Shoots
A method for accelerating growth of soybean shoots is desired.
-
Efficient Chromosome Doubling: Plant Cell Division
The Seeker is looking for an efficient chromosome doubling method in plants and in particular, metho...
- More Challenges
- Powered by:
nature jobs
Two year postdoctoral position in ethics, health and law
- University Paris Descartes
- Paris, 75 006, France
Research Scientist for Analytical Development
- Novo Nordisk
- Bagsværd, Denmark
Review article Nuclear factor-
B in cancer development and progression
Michael Karin1
Abstract
Nuclear factor-
B (NF-B) transcription factors and the signalling pathways that activate them are central coordinators of innate and adaptive immune responses. More recently, it has become clear that NF-B signalling also has a critical role in cancer development and progression. NF-B provides a mechanistic link between inflammation and cancer, and is a major factor controlling the ability of both pre-neoplastic and malignant cells to resist apoptosis-based tumour-surveillance mechanisms. NF-B might also regulate tumour angiogenesis and invasiveness, and the signalling pathways that mediate its activation provide attractive targets for new chemopreventive and chemotherapeutic approaches.
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
