Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 443, 37-38 (7 September 2006) | doi:10.1038/nature05003; Published online 16 August 2006
Open Innovation Challenges
-
Novel Approaches to Protecting Maize from Insect Damage
The Seeker is looking for novel approaches to protecting maize from insect damage. This Challenge re...
-
Single-cell Analysis Platform
This Challenge is looking for novel approaches to analyzing changes at a single-cell level. This is...
- More Challenges
- Powered by:
nature jobs
Basic Science Medical Educators
- Texas Tech University Health Sciences Center
- El Paso, Texas, USA
Flash Animator
- Indegene Lifesystems Pvt. Ltd
- Bengaluru 560 071 India
Structural biology: Antiviral drugs fit for a purpose
Ming Luo1
Abstract
Did drug researchers have a lucky break when they developed antiviral drugs for influenza? Crystal structures of enzymes from the H5N1 virus suggest that they did, and provide avenues for further exploration.
Oseltamivir (Tamiflu) and zanamivir (Relenza) have been stockpiled by several nations to counter the threat of a flu pandemic, should the highly pathogenic avian influenza virus H5N1 develop into a human strain. These drugs are inhibitors of an enzyme known as neuraminidase, which is found on the surface of the flu virus.
- Ming Luo is in the Department of Microbiology, University of Alabama, Birmingham, 1025 18th Street South, Birmingham, Alabama 35294, USA.
Email: mingluo@uab.edu
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
NEWS AND VIEWS
Extinct 1918 virus comes aliveNature Medicine News and Views (01 Nov 2005)
New clues to the emergence of flu pandemicsNature Medicine News and Views (01 Oct 1998)
RESEARCH
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug designNature Article (07 Sep 2006)
Influenza drug could abort a pandemicNature Correspondence (14 Apr 2005)
See all 11 matches for Research