Editorials

French science after Chirac p401

Presidential elections next spring are set to lend fresh impetus to research reform in France.

doi:10.1038/444401a

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Smiles all round p401

Can research buy you happiness?

doi:10.1038/444401b

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A fresh start for Japan p402

Japan has a new prime minister, a new science adviser, and a chance to change its science policy.

doi:10.1038/444402a

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Research Highlights

Research highlights p404

doi:10.1038/444404a

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News

Anti-evolutionists raise their profile in Europe p406

The teaching of alternative theories to evolution in schools is not just an issue in the United States. Almut Graebsch and Quirin Schiermeier assess whether creationism is threatening science in Europe.

doi:10.1038/444406a

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Q&A Peter Korevaar p407

Peter Korevaar is head of the physics and cosmology working group of Germany's Studiengemeinschaft Wort und Wissen, one of the largest creationist groups in Europe. He holds a PhD in astrophysics and now works at IBM in Mannheim. Quirin Schiermeier asks him about his group's aims.

doi:10.1038/444407a

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Tragedy increases woes of US ice fleet p408

Diver deaths spark safety concerns.

Rex Dalton

doi:10.1038/444408a

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Italian government eases in radical reforms p408

Changes to science policy get warm reception despite budget worries.

Alison Abbott

doi:10.1038/444408b

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Britain plans tough limits to curb emissions p409

Ambitious targets seek to tackle climate change.

Michael Hopkin

doi:10.1038/444409a

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Aboriginal remains head for home p411

UK museum's decision rattles researchers.

Jim Giles

doi:10.1038/444411a

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Sidelines p412

doi:10.1038/444412a

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Universities urged to do more for poor nations p412

Fruits of research should be made available to developing world, say critics.

Erika Check

doi:10.1038/444412b

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Snapshot: A night out in the park p413

Tyger! Tyger! Burning bright...

Erika Check

doi:10.1038/444413a

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News in brief p414

doi:10.1038/444414a

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Business

Nuclear's core business p415

The job of cleaning up Britain's nuclear plants is up for auction — so who might profit from the newly privatized industry? Andrea Chipman reports.

doi:10.1038/444415a

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News Features

Science in Africa: Conscious of change p416

Khotso Mokhele, formerly in charge of developing research in South Africa, talks to Michael Cherry about the role that science is playing in the nation's development.

doi:10.1038/444416a

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Well-being research: A measure of happiness p418

Philosophers since Aristotle have puzzled over the meaning of happiness. Tony Reichhardt asks what scientists, psychologists and economists can bring to the topic. Are we any closer to being able to quantify joy?

doi:10.1038/444418a

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See also: Editor's summary

Ecology: Spying on nature p420

The biggest project in the history of ecology is nearing its dawn. Can its organizers pull off the seemingly impossible and unite a disparate field behind its vision to observe the ecosystems of the United States? Michael Hopkin reports.

doi:10.1038/444420a

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Correspondence

The science community must unite over Iraq p422

Bengt Gustafsson

doi:10.1038/444422a

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German societies want to keep an international voice p422

Peter Gruss

doi:10.1038/444422b

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Imagine projects with a strong emotional appeal p422

Patricia Osseweijer

doi:10.1038/444422c

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Religious authorities overrule scientists in Iran p422

Kamran Behnia

doi:10.1038/444422d

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One small point p422

Rupert C. Marshall

doi:10.1038/444422e

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Books and Arts

Life in the universal porridge p423

What were the chances that the conditions in the Universe would be just right for life?

Jim Al-Khalili reviews The Goldilocks Enigma: Why Is the Universe Just Right for Life? by Paul Davies

doi:10.1038/444423a

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A giant leap? p424

James R. Hansen reviews Dark Side of the Moon: The Magnificent Madness of the American Lunar Quest by Gerard J. DeGroot

doi:10.1038/444424a

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Healthy fats p425

Asim K. Duttaroy reviews The Queen of Fats: Why Omega-3s Were Removed from the Western Diet and What We Can Do to Replace Them by Susan Allport

doi:10.1038/444425a

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Learning from nature p425

Robert W. Cahn reviews Biomimetics: Biologically Inspired Technologies edited by Yoseph Bar-Cohen

doi:10.1038/444425b

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Science in culture: Burning Bush p426

An exhibition in Australia highlights the country's bushfires.

Colin Martin

doi:10.1038/444426a

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News and Views

Solid-state physics: Super silicon p427

Silicon is the archetypal semiconductor, and base material of the microelectronic age. But it turns out that, treated the right way, silicon the semiconductor can become silicon the superconductor.

Robert J. Cava

doi:10.1038/444427a

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Human genomics: In search of normality p428

The first map of copy-number variation in the human genome has been created. It is now feasible to examine the role of such genome variation in disease and to explore in depth the extent of 'normal' variability.

Kevin V. Shianna and Huntington F. Willard

doi:10.1038/444428a

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Cell biology: Infectious Alzheimer's disease? p429

Accumulation of organized, self-polymerizing protein aggregates is a hallmark of Alzheimer's disease and infectious prion diseases. The similarities between these conditions may be even closer than that.

Roland Riek

doi:10.1038/444429a

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Spectroscopy: Molecular motion pictures p431

Molecules in solution change their conformations so quickly that no method has been able to record the process. This looks set to change, as infrared spectroscopy rises to the challenge.

Minhaeng Cho

doi:10.1038/444431a

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Medicine: Blastomeres and stem cells p432

Generating human stem cells from a single cell recovered during preimplantation genetic diagnosis does not, in principle, harm the embryo. Can the approach be used in assisted reproductive technology programmes?

Joe Leigh Simpson

doi:10.1038/444432a

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50 & 100 Years Ago p432

doi:10.1038/444432b

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Molecular biology: Triggering positive competition p435

In most bacteria, a molecule known as trigger factor prevents misfolding of newly made proteins emerging from their ribosome factory. The dynamic action of this molecule has been followed using fluorescence spectroscopy.

Ada Yonath

doi:10.1038/444435a

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Correction p436

doi:10.1038/444436a

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Brief Communications

Mullite and the mystery of Hessian wares p437

Crucibles popular in the Middle Ages owed their success to an ingredient used in modern ceramics.

Marcos Martinón-Torres, Thilo Rehren and Ian C. Freestone

doi:10.1038/444437a

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Synaesthesia: The taste of words on the tip of the tongue p438

Julia Simner and Jamie Ward

doi:10.1038/444438a

Full Text | PDF (112K) | Supplementary information

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Brief Communications Arising

Astrochemistry: Complex organic matter in Titan's aerosols? pE6

K Biemann

doi:10.1038/nature05417

First paragraph | Full Text | PDF (80K)

Astrochemistry: Complex organic matter in Titan's aerosols? (Reply) pE6

G. Israël, C. Szopa, F. Raulin, M. Cabane, H. B. Niemann, S. K. Atreya, S. J. Bauer, J.-F. Brun, E. Chassefière, P. Coll, E. Condé, D. Coscia, A. Hauchecorne, P. Millian, M. J. Nguyen, T. Owen, W. Riedler, R. E. Samuelson, J.-M. Siguier, M. Steller, R. Sternberg and C. Vidal-Madjar

doi:10.1038/nature05418

First paragraph | Full Text | PDF (85K)

Corrigendum pE8

doi:10.1038/nature05460

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Articles

Dynamics of seismogenic volcanic extrusion at Mount St Helens in 2004–05 p439

Richard M. Iverson, Daniel Dzurisin, Cynthia A. Gardner, Terrence M. Gerlach, Richard G. LaHusen, Michael Lisowski, Jon J. Major, Stephen D. Malone, James A. Messerich, Seth C. Moran, John S. Pallister, Anthony I. Qamar, Steven P. Schilling and James W. Vallance

doi:10.1038/nature05322

Abstract | Full Text | PDF (715K) | Supplementary information

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Global variation in copy number in the human genome p444

Richard Redon, Shumpei Ishikawa, Karen R. Fitch, Lars Feuk, George H. Perry, T. Daniel Andrews, Heike Fiegler, Michael H. Shapero, Andrew R. Carson, Wenwei Chen, Eun Kyung Cho, Stephanie Dallaire, Jennifer L. Freeman, Juan R. González, Mònica Gratacòs, Jing Huang, Dimitrios Kalaitzopoulos, Daisuke Komura, Jeffrey R. MacDonald, Christian R. Marshall, Rui Mei, Lyndal Montgomery, Kunihiro Nishimura, Kohji Okamura, Fan Shen, Martin J. Somerville, Joelle Tchinda, Armand Valsesia, Cara Woodwark, Fengtang Yang, Junjun Zhang, Tatiana Zerjal, Jane Zhang, Lluis Armengol, Donald F. Conrad, Xavier Estivill, Chris Tyler-Smith, Nigel P. Carter, Hiroyuki Aburatani, Charles Lee, Keith W. Jones, Stephen W. Scherer and Matthew E. Hurles

doi:10.1038/nature05329

Abstract | Full Text | PDF (1,166K) | Supplementary information

See also: Editor's summary | News and Views by Shianna & Willard

Real-time observation of trigger factor function on translating ribosomes p455

Christian M. Kaiser, Hung-Chun Chang, Vishwas R. Agashe, Sathish K. Lakshmipathy, Stephanie A. Etchells, Manajit Hayer-Hartl, F. Ulrich Hartl and José M. Barral

doi:10.1038/nature05225

Abstract | Full Text | PDF (1,590K) | Supplementary information

See also: Editor's summary | News and Views by Yonath

Letters

Magnetic vortex core reversal by excitation with short bursts of an alternating field p461

B. Van Waeyenberge, A. Puzic, H. Stoll, K. W. Chou, T. Tyliszczak, R. Hertel, M. Fähnle, H. Brückl, K. Rott, G. Reiss, I. Neudecker, D. Weiss, C. H. Back and G. Schütz

doi:10.1038/nature05240

First paragraph | Full Text | PDF (547K) | Supplementary information

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Superconductivity in doped cubic silicon p465

E. Bustarret, C. Marcenat, P. Achatz, J. Kamarik, F. Lévy, A. Huxley, L. Ortéga, E. Bourgeois, X. Blase, D. Débarre and J. Boulmer

doi:10.1038/nature05340

First paragraph | Full Text | PDF (507K)

See also: Editor's summary | News and Views by Cava

Watching hydrogen-bond dynamics in a -turn by transient two-dimensional infrared spectroscopy p469

Christoph Kolano, Jan Helbing, Mariusz Kozinski, Wolfram Sander and Peter Hamm

doi:10.1038/nature05352

First paragraph | Full Text | PDF (602K) | Supplementary information

See also: News and Views by Cho

Slip zone and energetics of a large earthquake from the Taiwan Chelungpu-fault Drilling Project p473

Kuo-Fong Ma, Hidemi Tanaka, Sheng-Rong Song, Chien-Ying Wang, Jih-Hao Hung, Yi-Ben Tsai, Jim Mori, Yen-Fang Song, Eh-Chao Yeh, Wonn Soh, Hiroki Sone, Li-Wei Kuo and Hung-Yu Wu

doi:10.1038/nature05253

First paragraph | Full Text | PDF (500K) | Supplementary information

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Ecological consequences of major hydrodynamic disturbances on coral reefs p477

Joshua S. Madin and Sean R. Connolly

doi:10.1038/nature05328

First paragraph | Full Text | PDF (514K) | Supplementary information

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Human embryonic stem cell lines derived from single blastomeres p481

Irina Klimanskaya, Young Chung, Sandy Becker, Shi-Jiang Lu and Robert Lanza

doi:10.1038/nature05142

First paragraph | Full Text | PDF (2,039K) | Supplementary information

See also: Editor's summary | News and Views by Simpson

Endogenous neurosteroids regulate GABA_A receptors through two discrete transmembrane sites p486

Alastair M. Hosie, Megan E. Wilkins, Helena M. A. da Silva and Trevor G. Smart

doi:10.1038/nature05324

First paragraph | Full Text | PDF (555K) | Supplementary information

Self-incompatibility in Papaver targets soluble inorganic pyrophosphatases in pollen p490

Barend H. J. de Graaf, Jason J. Rudd, Michael J. Wheeler, Ruth M. Perry, Elizabeth M. Bell, Kim Osman, F. Christopher H. Franklin and Vernonica E. Franklin-Tong

doi:10.1038/nature05311

First paragraph | Full Text | PDF (241K) | Supplementary information

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Polo kinase controls cell-cycle-dependent transcription by targeting a coactivator protein p494

Zoulfia Darieva, Richard Bulmer, Aline Pic-Taylor, Kathryn S. Doris, Marco Geymonat, Steven G. Sedgwick, Brian A. Morgan and Andrew D. Sharrocks

doi:10.1038/nature05339

First paragraph | Full Text | PDF (1,402K) | Supplementary information

In vivo enhancer analysis of human conserved non-coding sequences p499

Len A. Pennacchio, Nadav Ahituv, Alan M. Moses, Shyam Prabhakar, Marcelo A. Nobrega, Malak Shoukry, Simon Minovitsky, Inna Dubchak, Amy Holt, Keith D. Lewis, Ingrid Plajzer-Frick, Jennifer Akiyama, Sarah De Val, Veena Afzal, Brian L. Black, Olivier Couronne, Michael B. Eisen, Axel Visel and Edward M. Rubin

doi:10.1038/nature05295

First paragraph | Full Text | PDF (316K) | Supplementary information

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Structure of the E. coli signal recognition particle bound to a translating ribosome p503

Christiane Schaffitzel, Miro Oswald, Imre Berger, Takashi Ishikawa, Jan Pieter Abrahams, Henk K. Koerten, Roman I. Koning and Nenad Ban

doi:10.1038/nature05182

First paragraph | Full Text | PDF (2,167K) | Supplementary information

Following the signal sequence from ribosomal tunnel exit to signal recognition particle p507

Mario Halic, Michael Blau, Thomas Becker, Thorsten Mielke, Martin R. Pool, Klemens Wild, Irmgard Sinning and Roland Beckmann

doi:10.1038/nature05326

First paragraph | Full Text | PDF (1,413K) | Supplementary information

Addendum

Human embryonic stem cell lines derived from single blastomeres p512

Irina Klimanskaya, Young Chung, Sandy Becker, Shi-Jiang Lu and Robert Lanza

doi:10.1038/nature05366

Full Text | PDF (60K) | Supplementary information

Erratum

Eastern Pacific cooling and Atlantic overturning circulation during the last deglaciation p512

Markus Kienast, Stephanie S. Kienast, Stephen E. Calvert, Timothy I. Eglinton, Gesine Mollenhauer, Roger François and Alan C. Mix

doi:10.1038/nature05377

Full Text | PDF (60K) | Supplementary information

Corrigenda

Insights into social insects from the genome of the honeybee Apis mellifera p512

The Honeybee Genome Sequencing Consortium

doi:10.1038/nature05400

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Potential of stem-cell-based therapies for heart disease p512

Deepak Srivastava and Kathryn N. Ivey

doi:10.1038/nature05423

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Naturejobs

Prospects p513

Funding initiative offers boost for young scientists in Germany.

Paul Smaglik

doi:10.1038/nj7118-513a

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Small talk p514

Nanobiotechnology is a growing field, but will it emulate the biotech boom? Virginia Gewin investigates.

Virginia Gewin

doi:10.1038/nj7118-514a

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Robert Huber, professor, Cardiff University, Cardiff, UK p516

Robert Huber continues to help advance structural biology.

Virginia Gewin

doi:10.1038/nj7118-516a

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Unhealthy choices p516

Monya Baker

doi:10.1038/nj7118-516b

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Roller hockey or science? p516

Sometimes I wonder what I'd do instead of science.

Milan de Vries

doi:10.1038/nj7118-516c

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Highlight: Germany's Excellence Initiative

doi:10.1038/nj0134

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Futures

The liquidators p518

A rose by any other name.

Michael Garrett Farrelly

doi:10.1038/444518a

Full Text | PDF (286K)