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Editorials

Resurgent nuclear threats p107

The world faces great risks from nuclear weapons that need to be urgently addressed by political leaders and scientists worldwide. There is now a window of opportunity to do so.

doi:10.1038/451107a


Don't panic p108

Whether to build the International Linear Collider is an open question, but R&D on it should be supported.

doi:10.1038/451108a


Spread the word p108

Evolution is a scientific fact, and every organization whose research depends on it should explain why.

doi:10.1038/451108b


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Research Highlights

Research highlights p110

doi:10.1038/451110a


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Journal Club

Journal club p111

Dirk Brockmann

doi:10.1038/451111a


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News

Accelerator plans stalled after US and UK cuts p112

Budget woes spell trouble for International Linear Collider.

Eric Hand & Geoff Brumfiel

doi:10.1038/451112a


India aims for 'quantum jump' in science p112

Government plans multiple universities and hikes science spending.

K. S. Jayaraman

doi:10.1038/451112b


Could global gardening fix climate change? p113

Biomass proposal could hugely reduce carbon dioxide levels.

Jeff Tollefson

doi:10.1038/451113a


Nuclear war: the threat that never went away p114

In the first of a series of articles covering nuclear issues, Declan Butler looks at the nuclear non-proliferation treaty and finds that there has never been a better climate for negotiation.

Declan Butler

doi:10.1038/451114a


China bows to public over chemical plant p117

Environmental protesters score landmark victory.

Jane Qiu

doi:10.1038/451117a


Sidelines p117

Scribbles on the margins of science.

doi:10.1038/451117b


Fears for oldest human footprints p118

Fossilized tracks pose preservation puzzle.

Rex Dalton

doi:10.1038/451118a


Snapshot: Making light work of indoor gardening p119

Car manufacturers give plants a healthy glow.

David Cyranoski

doi:10.1038/451119a


Software magnates give $30 million to telescope p121

doi:10.1038/451121a


Creator and first chair of climate-change panel dies p121

doi:10.1038/451121b


China amends patent-rights law to boost innovation p121

doi:10.1038/451121c


Zoo's abandoned polar bear cubs 'will be left to die' p121

doi:10.1038/451121d


National Academies updates book on evolution p121

doi:10.1038/451121e


A colourful discovery in Costa Rica p121

doi:10.1038/451121f


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News Features

Conservation: Providential outcome p122

A winning combination of isolation, local involvement and a broad ecological remit are making the management of the seas around Colombia's San Andrés islands a model for other conservationists, reports Mark Schrope.

doi:10.1038/451122a


Cell biology: Bacteria's new bones p124

Long dismissed as featureless, disorganized sacks, bacteria are now revealing a multitude of elegant internal structures. Ewen Callaway investigates a new field in cell biology.

doi:10.1038/451124a


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Correspondence

Conservation: in a rut, we need rut-inspired solutions p127

Kai M. A. Chan

doi:10.1038/451127a


Conservation: academics should 'conserve or perish' p127

Guillaume Chapron & Raphaël Arlettaz

doi:10.1038/451127b


Frog transparency led to discovery of melatonin p127

Thomas C. Erren, Russel J. Reiter & V. Benno Meyer-Rochow

doi:10.1038/451127c


Schizophrenia is a disease, so electrons aren't at risk p127

Ronald Chase

doi:10.1038/451127d


Schizophrenia does not mean split personality p127

Alex C. W. May

doi:10.1038/451127e


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Books and Arts

From bench to book p128

Web publishing and marketing might put more science into fiction and attract new readers.

Jennifer Rohn reviews A Version of the Truth by Jennifer Kaufman & Karen Mack and The Gift: Discovery, Treachery & Revenge by Jon Kalb and The Expeditions by Karl Iagnemma

doi:10.1038/451128a

See also: Editor's summary


Exhibition: Dreamscapes p129

Henry Nicholls

doi:10.1038/451129a


Rex appeal p129

Frank A. J. L. James reviews The Earth on Show: Fossils and the Poetics of Popular Science, 1802–1856 by Ralph O'Connor and Victorian Popularizers of Science: Designing Nature for New Audiences by Bernard Lightman

doi:10.1038/451129b


Pulling power p130

Sean Carroll reviews The Universal Force: Gravity, Creator of Worlds by Louis A. Girifalco

doi:10.1038/451130a


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News and Views

Molecular biology: RNA rules p131

Studies of an old genetic puzzle in a little-known protozoan reveal a new frontier in the expanding world of RNAs: an RNA template guides genome-wide DNA rearrangements during sexual reproduction.

Meng-Chao Yao

doi:10.1038/451131a

See also: Editor's summary


Materials science: Desperately seeking silicon p132

Using silicon as a 'thermoelectric' material to convert heat into electricity would be a technological leap forward. But silicon conducts heat so well that nobody thought that could work — until now.

Cronin B. Vining

doi:10.1038/451132a


Palaeontology: Ancient worms in armour p133

It requires a quirk of fossilization for the soft parts of an animal to be preserved. Study of such a specimen of the mysterious machaeridians provides these organisms with a well defined evolutionary home.

Jean-Bernard Caron

doi:10.1038/451133a

See also: Editor's summary


Conservation biology: Cats, rats and seabirds p134

Cats kill birds, and therefore eradicating cats from an island would seem to be a good strategy for protecting the native population of seabirds. But that thinking does not take account of ecological complications.

Matthieu Le Corre

doi:10.1038/451134a


Stem cells: A new year and a new era p135

Manipulating cells from adult human tissue, scientists have generated cells with the same developmental potential as embryonic stem cells. The research opportunities these exciting observations offer are limitless.

Martin F. Pera

doi:10.1038/451135a

See also: Editor's summary


Physics: The force of fluctuations p136

Strange forces and effects dominate the world at the microscopic level. One such force, rooted in the random fluctuations of matter, has only now been accurately measured — 30 years after it was first predicted.

Sébastien Balibar

doi:10.1038/451136a


Quantum mechanics: Evolution stopped in its tracks p137

How do you watch the evolution of something that doesn't evolve? In the classical world, even posing this question would provoke raised eyebrows. But where quantum physics is involved, no question is too silly.

Lev Vaidman

doi:10.1038/451137a

See also: Editor's summary


Obituary: Seymour Benzer (1921–2007) p139

Restless spirit, and pioneer in molecular genetics.

David Anderson & Sydney Brenner

doi:10.1038/451139a


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Articles

Reprogramming of human somatic cells to pluripotency with defined factors p141

In-Hyun Park, Rui Zhao, Jason A. West, Akiko Yabuuchi, Hongguang Huo, Tan A. Ince, Paul H. Lerou, M. William Lensch & George Q. Daley

doi:10.1038/nature06534

See also: Editor's summary | News and Views by Pera


Endogenous human microRNAs that suppress breast cancer metastasis p147

Sohail F. Tavazoie, Claudio Alarcón, Thordur Oskarsson, David Padua, Qiongqing Wang, Paula D. Bos, William L. Gerald & Joan Massagué

doi:10.1038/nature06487

See also: Editor's summary


RNA-mediated epigenetic programming of a genome-rearrangement pathway p153

Mariusz Nowacki, Vikram Vijayan, Yi Zhou, Klaas Schotanus, Thomas G. Doak & Laura F. Landweber

doi:10.1038/nature06452

See also: Editor's summary | News and Views by Yao


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Letters

An asymmetric distribution of positrons in the Galactic disk revealed by bold gamma-rays p159

Georg Weidenspointner, Gerry Skinner, Pierre Jean, Jürgen Knödlseder, Peter von Ballmoos, Giovanni Bignami, Roland Diehl, Andrew W. Strong, Bertrand Cordier, Stéphane Schanne & Christoph Winkler

doi:10.1038/nature06490

See also: Editor's summary


Enhanced thermoelectric performance of rough silicon nanowires p163

Allon I. Hochbaum, Renkun Chen, Raul Diaz Delgado, Wenjie Liang, Erik C. Garnett, Mark Najarian, Arun Majumdar & Peidong Yang

doi:10.1038/nature06381

See also: Editor's summary | News and Views by Vining


Silicon nanowires as efficient thermoelectric materials p168

Akram I. Boukai, Yuri Bunimovich, Jamil Tahir-Kheli, Jen-Kan Yu, William A. Goddard III & James R. Heath

doi:10.1038/nature06458

See also: Editor's summary | News and Views by Vining


Direct measurement of critical Casimir forces p172

C. Hertlein, L. Helden, A. Gambassi, S. Dietrich & C. Bechinger

doi:10.1038/nature06443

See also: News and Views by Balibar


Crude-oil biodegradation via methanogenesis in subsurface petroleum reservoirs p176

D. M. Jones, I. M. Head, N. D. Gray, J. J. Adams, A. K. Rowan, C. M. Aitken, B. Bennett, H. Huang, A. Brown, B. F. J. Bowler, T. Oldenburg, M. Erdmann & S. R. Larter

doi:10.1038/nature06484

See also: Editor's summary


Seismic identification of along-axis hydrothermal flow on the East Pacific Rise p181

M. Tolstoy, F. Waldhauser, D. R. Bohnenstiehl, R. T. Weekly & W.-Y. Kim

doi:10.1038/nature06424

See also: Editor's summary


Machaeridians are Palaeozoic armoured annelids p185

Jakob Vinther, Peter Van Roy & Derek E. G. Briggs

doi:10.1038/nature06474

See also: Editor's summary | News and Views by Caron


The coevolution of choosiness and cooperation p189

John M. McNamara, Zoltan Barta, Lutz Fromhage & Alasdair I. Houston

doi:10.1038/nature06455

See also: Editor's summary


Identification of the sex genes in an early diverged fungus p193

Alexander Idnurm, Felicia J. Walton, Anna Floyd & Joseph Heitman

doi:10.1038/nature06453

See also: Editor's summary


Ultra-fine frequency tuning revealed in single neurons of human auditory cortex p197

Y. Bitterman, R. Mukamel, R. Malach, I. Fried & I. Nelken

doi:10.1038/nature06476


Epigenetic silencing of tumour suppressor gene p15 by its antisense RNA p202

Wenqiang Yu, David Gius, Patrick Onyango, Kristi Muldoon-Jacobs, Judith Karp, Andrew P. Feinberg & Hengmi Cui

doi:10.1038/nature06468


Abscisic acid controls calcium-dependent egress and development in Toxoplasma gondii p207

Kisaburo Nagamune, Leslie M. Hicks, Blima Fux, Fabien Brossier, Eduardo N. Chini & L. David Sibley

doi:10.1038/nature06478

See also: Editor's summary


Defective tryptophan catabolism underlies inflammation in mouse chronic granulomatous disease p211

Luigina Romani, Francesca Fallarino, Antonella De Luca, Claudia Montagnoli, Carmen D'Angelo, Teresa Zelante, Carmine Vacca, Francesco Bistoni, Maria C. Fioretti, Ursula Grohmann, Brahm H. Segal & Paolo Puccetti

doi:10.1038/nature06471

See also: Editor's summary


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Erratum

Two stellar components in the halo of the Milky Way p216

Daniela Carollo, Timothy C. Beers, Young Sun Lee, Masashi Chiba, John E. Norris, Ronald Wilhelm, Thirupathi Sivarani, Brian Marsteller, Jeffrey A. Munn, Coryn A. L. Bailer-Jones, Paola Re Fiorentin & Donald G. York

doi:10.1038/nature06542


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Naturejobs

Prospect

Prospects p217

A controversial move to central London for the Medical Research Council's flagship lab will have career repercussions.

Paul Smaglik

doi:10.1038/nj7175-217a


Special Report

A career at the museum p218

For scientists who want to combine public outreach with research, a museum may be the perfect place to work, says Ricki Lewis.

Ricki Lewis

doi:10.1038/nj7175-218a


Highlights

Opportunities: The National Institutes of Health

doi:10.1038/nj0193


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Futures

Zed's fanverse p222

It's only a game...

Toiya Kristen Finley

doi:10.1038/451222a


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