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Nature 452, 548-552 (3 April 2008) | doi:10.1038/nature06913; Published online 2 April 2008
Open Innovation Challenges
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Efficient Chromosome Doubling: Plant Cell Division
The Seeker is looking for an efficient chromosome doubling method in plants and in particular, metho...
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Protect Enzyme from In Planta Degradation
A proposal for stable expression of an enzyme in corn seed is desired.
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Postdoctoral Research Fellow positions - Brain and Cognitive Sciences
- University of Toronto, Seoul National University
- Seoul Korea, Toronto, ON Canada
Cells for Sight Tissue Bank Manager (Cellular Therapies)
- University College London, Division of Ocular Biology and Therapeutics
- London, EC1V 9EL UK
Overview Article The cancer biomarker problem
Charles L. Sawyers1
Abstract
Genomic technologies offer the promise of a comprehensive understanding of cancer. These technologies are being used to characterize tumours at the molecular level, and several clinical successes have shown that such information can guide the design of drugs targeted to a relevant molecule. One of the main barriers to further progress is identifying the biological indicators, or biomarkers, of cancer that predict who will benefit from a particular targeted therapy.
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