Access
To read this story in full you will need to login or make a payment (see right).
News and Views
Nature 453, 863-864 (12 June 2008) | doi:10.1038/nature06365; Published online 11 June 2008
nature jobs
Senior Staff Scientist (Ref 80251)
- Wellcome Trust Sanger Institute
- Cambridge CB10 1SA United Kingdom
Lecturer in Medical Bacteriology
- University of Strathclyde Glasgow
- Glasgow United Kingdom
Huntington's disease: Genetics lends a hand
Stéphane Palfi1 & Bechir Jarraya1
Abstract
A monkey model of Huntington's disease created by gene transfer is only a work in progress. But as a technological feat it offers great promise for fathoming this devastating condition.
Huntington's disease is a heritable disorder that affects more than 1 in 10,000 people. Its associated neurological symptoms are severe, and there is no therapy to halt or slow its progress.
- Stéphane Palfi and Bechir Jarraya are in the CEA/DSV/I2BM–MIRCen, Fontenay-aux-Roses, and at the Assistance Publique-Hôpitaux de Paris, l'Hôpital Henri Mondor, Service de Neurochirurgie, Université Paris 12, Faculté de Médecine, Créteil F-94010, France.
Email: stephane.palfi@hmn.aphp.fr
To read this story in full you will need to login or make a payment (see right).
MORE ARTICLES LIKE THIS
These links to content published by NPG are automatically generated.
RESEARCH
Expression of Mutated Huntingtin Fragment in the Putamen Is Sufficient to Produce Abnormal Movement in Non-human PrimatesMolecular Therapy Original Article
Expression of Mutated Huntingtin Fragment in the Putamen Is Sufficient to Produce Abnormal Movement in Non-human PrimatesMolecular Therapy Original Article
