Table of contents
Volume 453 Number 7199 pp1143-1284
(this content only available online) indicates content that is available online only
Editorials
The unlikely matters p1143
The study of cosmic impacts and the effects they have offers two lessons for students of science.
doi:10.1038/4531143a
See also: Editor's summary
Unbalanced portfolio p1144
British research councils should still foster basic science.
doi:10.1038/4531144a
Comédie-Française p1144
Regional and minority languages should be protected, in France, and elsewhere.
doi:10.1038/4531144b
Research Highlights
Zoology: Spotted! p1146
doi:10.1038/4531146a
Statistics: Who's the driver? p1146
doi:10.1038/4531146b
Evolution: Model lives p1146
doi:10.1038/4531146c
Materials science: Diatomic power p1146
doi:10.1038/4531146d
Microbiology: Infection injection p1146
doi:10.1038/4531146e
Geoscience: The geyser forecast p1146
doi:10.1038/4531146f
Genetics: The Mod Squad p1147
doi:10.1038/4531147a
Physiology: Environmental awareness p1147
doi:10.1038/4531147b
Cell biology: Motor control p1147
doi:10.1038/4531147c
Microfluidics: Groove train p1147
doi:10.1038/4531147d
News
Gene-testing firms face legal battle p1148
The state of California is clamping down on companies that offer direct-to-consumer genetic testing in a move that threatens the burgeoning industry. Meredith Wadman looks at a grey area in US regulation.
Meredith Wadman
doi:10.1038/4531148a
Biogen fights takeover bid p1149
Board members reject billionaire's plans.
Heidi Ledford
doi:10.1038/4531149a
Scientists get online news aggregator p1149
Canadian researcher launches science version of Google News.
Declan Butler
doi:10.1038/4531149b
Payback time p1150
The UK government has invested heavily in science. Now it's looking for a return, and some worry that the research councils are being pressured to deliver, possibly at the expense of 'blue skies' research. Geoff Brumfiel looks at the changing landscape of science funding in Britain.
Geoff Brumfiel
doi:10.1038/4531150a
When water gushed on Mars p1153
Could crevasses in the ice have been caused by a recent volcanic eruption?
Eric Hand
doi:10.1038/4531153a
Population genomics for fruitflies p1154
Aggressive drosophila prompt study of genetic make-up.
Heidi Ledford
doi:10.1038/4531154a
Online anthropology draws protest from aboriginal group p1155
South African tribe objects to multimedia images of remains.
Tony Scully
doi:10.1038/4531155a
Sidelines p1155
Scribbles on the margins of science.
doi:10.1038/4531155b
US Congress signals new funds for key science areas p1156
doi:10.1038/4531156a
Boost biosafety funding to cut risks, say UK officials p1156
doi:10.1038/4531156b
Phoenix digger uncovers ice in Martian soil p1156
doi:10.1038/4531156c
International stem-cell collaborations launched p1156
doi:10.1038/4531156d
Latest satellite launches to monitor sea level p1156
doi:10.1038/4531156e
Radar and wind farms should coexist, say advisers p1156
doi:10.1038/4531156f
News Features
Planetary science: Tunguska at 100 p1157
The most dramatic cosmic impact in recent history has gathered up almost as many weird explanations as it knocked down trees, writes Duncan Steel.
doi:10.1038/4531157a
Planetary science: The hole at the bottom of the Moon p1160
A giant crater on the lunar farside holds the key to a catastrophic bombardment that reshaped the Moon, Earth and other planets. Eric Hand reports.
doi:10.1038/4531160a
Planetary science: The burger bar that saved the world p1164
Fewer people are searching for near-Earth asteroids, astronomer David Morrison said in the 1990s, than work a shift in a small McDonalds. But that group — a little larger now — has over the past two decades discovered a host of happily harmless rocks, and in doing so reduced the risk of an unknown asteroid blighting civilization (see page 1178). David Chandler puts together the story in the words of those who watched, and those who watched the watchers.
doi:10.1038/4531164a
Gallery feature: All craters great and small p1170
From a 5-millimetre dent on a satellite to a 3-kilometre pit in the surface of Mars, the scars of impact events can be seen at every scale. We present a gallery of some particularly appealing ones from Earth and beyond.
doi:10.1038/4531170a
Correspondence
Agronomy and plant breeding are key to combating food crisis p1177
Lucas Borrás & Gustavo A. Slafer
doi:10.1038/4531177a
The ethical basis of the null hypothesis p1177
John Pastor
doi:10.1038/4531177b
Stem-cell urological treatment was not carried out illegally p1177
Hannes Strasser
doi:10.1038/4531177c
Commentary
What Spaceguard did p1178
A survey of large objects near Earth has shown that there is little risk of a cataclysmic impact in the next century. Alan Harris asks if such cataloguing efforts should continue.
doi:10.1038/4531178a
See also: Editor's summary
Books and Arts
The end of the line? p1180
A spotlight on the historic US fishing port of Gloucester fails to capture the complexity of the fisheries collapse caused by overexploitation and regulation, says Daniel Pauly.
Daniel Pauly reviews The Last Fish Tale: The Fate of the Atlantic and Survival in Gloucester, America's Oldest Fishing Port and Most Original Town by Mark Kurlansky
doi:10.1038/4531180a
Making genetic history p1181
Jerry A. Coyne reviews In Pursuit of the Gene: From Darwin to DNA by James Schwartz
doi:10.1038/4531181a
Swayonomics p1182
Michael Shermer reviews Sway: The Irresistible Pull of Irrational Behavior by Ori Brafman & Rom Brafman
doi:10.1038/4531182a
Q&A: Travels with a paintbrush p1183
Watercolour artist and explorer Tony Foster paints in some extreme places. He has climbed mountains, sketched erupting volcanoes and drawn underwater. As an exhibition of his works of Mount Everest and the Grand Canyon opens in London, he tells Nature why he goes to such extraordinary efforts.
Daniel Cressey
doi:10.1038/4531183a
In Retrospect: Lucifer's Hammer p1184
Oliver Morton recalls how the first major science fiction novel to depict an impact event conjured the thrill and the horror of natural cataclysm — and even inspired some researchers.
Oliver Morton reviews Lucifer's Hammer by Larry Niven & Jerry Pournelle
doi:10.1038/4531184a
Message from the heavens p1185
Discerning the meaning behind Maurizio Cattelan's violent, provocative and now highly valuable sculpture of Pope John Paul II felled by a meteorite raises many questions for viewers, explains Martin Kemp.
Martin Kemp
doi:10.1038/4531185a
Essays
Beyond the notes p1186
The way performers shape notes brings music to life. Nicholas Cook argues that measuring these subtle changes can help us appreciate and replicate the performer's art.
Nicholas Cook
doi:10.1038/4531186a
The other beetle-hunter p1188
Thanks to a fateful letter, the theory of evolution by natural selection was unveiled 150 years ago this week. Andrew Berry and Janet Browne celebrate the letter's writer, Alfred Russel Wallace.
Andrew Berry & Janet Browne
doi:10.1038/4531188a
News and Views
Planetary science: Forming the martian great divide p1191
Early in its history, Mars suffered a convulsion that left a lasting geological and topographical scar. The latest work adds to evidence that the cause was external — a massive impact.
Walter S. Kiefer
doi:10.1038/4531191a
See also: Editor's summary
Behavioural neuroscience: Out of sight, but not out of mind p1192
Flies are cleverer than previously thought. They can remember their original destination even if distracted en route by another landmark. This behaviour depends on a specific group of neurons.
Seth M. Tomchik & Ronald L. Davis
doi:10.1038/4531192a
See also: Editor's summary
50 & 100 Years Ago p1193
doi:10.1038/4531193a
Drug discovery: A lifeline for suffocating tissues p1194
When a blood vessel becomes blocked, the ideal treatment would be a drug that induces new vessel formation in the damaged tissue, without affecting healthy tissues. With the chemical nitrite, we might be on to a winner.
Massimiliano Mazzone & Peter Carmeliet
doi:10.1038/4531194a
Atmospheric chemistry: Sun, sea and ozone destruction p1195
Halogens are known to decrease the levels of stratospheric ozone. The latest measurements show that something similar occurs in the lower atmosphere over tropical oceans — and probably above most other oceans, too.
Roland von Glasow
doi:10.1038/4531195a
See also: Editor's summary
Psychology: Bias at the ballot box p1197
Tim Lincoln
doi:10.1038/4531197a
Molecular biology: Power sequencing p1197
Advances in DNA-sequencing technology provide unprecedented insight into the entire collection of four genomes' transcribed sequences. They herald a new era in the study of gene regulation and genome function.
Brenton R. Graveley
doi:10.1038/4531197b
See also: Editor's summary
Articles
Ventastega curonica and the origin of tetrapod morphology p1199
Per E. Ahlberg,
Jennifer A. Clack,
Erv
ns Luk
evi
s,
Henning Blom
&
Ivars Zupi

doi:10.1038/nature06991
Abstract | Full Text | PDF (1,495K) | Supplementary information
See also: Editor's summary
Scaling of the BMP activation gradient in Xenopus embryos p1205
Danny Ben-Zvi, Ben-Zion Shilo, Abraham Fainsod & Naama Barkai
doi:10.1038/nature07059
Abstract | Full Text | PDF (591K) | Supplementary information
See also: Editor's summary
Letters
The Borealis basin and the origin of the martian crustal dichotomy p1212
Jeffrey C. Andrews-Hanna, Maria T. Zuber & W. Bruce Banerdt
doi:10.1038/nature07011
First paragraph | Full Text | PDF (641K) | Supplementary information
See also: Editor's summary | News and Views by Kiefer
Mega-impact formation of the Mars hemispheric dichotomy p1216
Margarita M. Marinova, Oded Aharonson & Erik Asphaug
doi:10.1038/nature07070
First paragraph | Full Text | PDF (1,429K) | Supplementary information
See also: Editor's summary | News and Views by Kiefer
Implications of an impact origin for the martian hemispheric dichotomy p1220
F. Nimmo, S. D. Hart, D. G. Korycansky & C. B. Agnor
doi:10.1038/nature07025
First paragraph | Full Text | PDF (2,102K) | Supplementary information
See also: Editor's summary | News and Views by Kiefer
A BCS-like gap in the superconductor SmFeAsO0.85F0.15 p1224
T. Y. Chen, Z. Tesanovic, R. H. Liu, X. H. Chen & C. L. Chien
doi:10.1038/nature07081
First paragraph | Full Text | PDF (525K) | Supplementary information
See also: Editor's summary
The total synthesis of (-)-cyanthiwigin F by means of double catalytic enantioselective alkylation p1228
John A. Enquist Jr & Brian M. Stoltz
doi:10.1038/nature07046
First paragraph | Full Text | PDF (316K) | Supplementary information
See also: Editor's summary
Extensive halogen-mediated ozone destruction over the tropical Atlantic Ocean p1232
Katie A. Read, Anoop S. Mahajan, Lucy J. Carpenter, Mathew J. Evans, Bruno V. E. Faria, Dwayne E. Heard, James R. Hopkins, James D. Lee, Sarah J. Moller, Alastair C. Lewis, Luis Mendes, James B. McQuaid, Hilke Oetjen, Alfonso Saiz-Lopez, Michael J. Pilling & John M. C. Plane
doi:10.1038/nature07035
First paragraph | Full Text | PDF (282K) | Supplementary information
See also: Editor's summary | News and Views by von Glasow
Explosive volcanism on the ultraslow-spreading Gakkel ridge, Arctic Ocean p1236
Robert A. Sohn, Claire Willis, Susan Humphris, Timothy M. Shank, Hanumant Singh, Henrietta N. Edmonds, Clayton Kunz, Ulf Hedman, Elisabeth Helmke, Michael Jakuba, Bengt Liljebladh, Julia Linder, Christopher Murphy, Ko-ichi Nakamura, Taichi Sato, Vera Schlindwein, Christian Stranne, Maria Tausenfreund, Lucia Upchurch, Peter Winsor, Martin Jakobsson & Adam Soule
doi:10.1038/nature07075
First paragraph | Full Text | PDF (648K)
See also: Editor's summary
Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolution p1239
Brian T. Wilhelm, Samuel Marguerat, Stephen Watt, Falk Schubert, Valerie Wood, Ian Goodhead, Christopher J. Penkett, Jane Rogers & Jürg Bähler
doi:10.1038/nature07002
First paragraph | Full Text | PDF (1,523K) | Supplementary information
See also: Editor's summary | News and Views by Graveley
Analysis of a spatial orientation memory in Drosophila p1244
Kirsa Neuser, Tilman Triphan, Markus Mronz, Burkhard Poeck & Roland Strauss
doi:10.1038/nature07003
First paragraph | Full Text | PDF (336K) | Supplementary information
See also: Editor's summary | News and Views by Tomchik & Davis
Hippocampus-independent phase precession in entorhinal grid cells p1248
Torkel Hafting, Marianne Fyhn, Tora Bonnevie, May-Britt Moser & Edvard I. Moser
doi:10.1038/nature06957
First paragraph | Full Text | PDF (1,023K) | Supplementary information
See also: Editor's summary
Rapid strengthening of thalamo-amygdala synapses mediates cue–reward learning p1253
Kay M. Tye, Garret D. Stuber, Bram de Ridder, Antonello Bonci & Patricia H. Janak
doi:10.1038/nature06963
First paragraph | Full Text | PDF (978K) | Supplementary information
See also: Editor's summary
Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants p1258
Patrick J. Collins, Lesley F. Haire, Yi Pu Lin, Junfeng Liu, Rupert J. Russell, Philip A. Walker, John J. Skehel, Stephen R. Martin, Alan J. Hay & Steven J. Gamblin
doi:10.1038/nature06956
First paragraph | Full Text | PDF (595K) | Supplementary information
See also: Editor's summary
Assembly reflects evolution of protein complexes p1262
Emmanuel D. Levy, Elisabetta Boeri Erba, Carol V. Robinson & Sarah A. Teichmann
doi:10.1038/nature06942
First paragraph | Full Text | PDF (829K) | Supplementary information
See also: Editor's summary
Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins p1266
Nathan HyunJoong Joh, Andrew Min, Salem Faham, Julian P. Whitelegge, Duan Yang, Virgil L. Woods & James U. Bowie
doi:10.1038/nature06977
First paragraph | Full Text | PDF (653K) | Supplementary information
See also: Editor's summary
Structural basis for EGFR ligand sequestration by Argos p1271
Daryl E. Klein, Steven E. Stayrook, Fumin Shi, Kartik Narayan & Mark A. Lemmon
doi:10.1038/nature06978
First paragraph | Full Text | PDF (817K) | Supplementary information
See also: Editor's summary
Translation factors promote the formation of two states of the closed-loop mRNP p1276
Nadia Amrani, Shubhendu Ghosh, David A. Mangus & Allan Jacobson
doi:10.1038/nature06974
First paragraph | Full Text | PDF (424K) | Supplementary information
See also: Editor's summary
Naturejobs
ProspectProspects p1281
Pruning the prickly path to industry.
Gene Russo
doi:10.1038/nj7199-1281a
Career View
James Halpert, Associate Dean for Scientific Affairs, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego p1282
Biochemist dares to take on new challenge.
Virginia Gewin
doi:10.1038/nj7199-1282a
Postdoc competencies p1282
The making of postdoc 'core competencies'.
Lisa Curtis, Keith Micoli & Jennifer Reineke Pohlhaus
doi:10.1038/nj7199-1282b
Cool and collected p1282
Mouth-watering T-bone dreams.
Aliza le Roux
doi:10.1038/nj7199-1282c

