Top 10
The top ten charts the articles that have been downloaded most often, in PDF format, from the Nature website in the last month. The chart does not rank the quality, scientific significance or citation impact of the content. However, it may bring articles to your attention that you might not have otherwise noticed. We hope you enjoy them.
Top of pageLast month's Nature top ten
Insight
The cancer biomarker problem
Charles L. Sawyers
doi:10.1038/nature06913
Letter
The complete genome of an individual by massively parallel DNA sequencing
David A. Wheeler, Maithreyan Srinivasan, Michael Egholm, Yufeng Shen, Lei Chen, Amy McGuire, Wen He, Yi-Ju Chen, Vinod Makhijani, G. Thomas Roth, Xavier Gomes, Karrie Tartaro, Faheem Niazi, Cynthia L. Turcotte, Gerard P. Irzyk, James R. Lupski, Craig Chinault, Xing-zhi Song, Yue Liu, Ye Yuan, Lynne Nazareth, Xiang Qin, Donna M. Muzny, Marcel Margulies, George M. Weinstock, Richard A. Gibbs & Jonathan M. Rothberg
doi:10.1038/nature06884
Abstract | Full Text | PDF (264K) | Supplementary information
Article
Sequence- and target-independent angiogenesis suppression by siRNA via TLR3
Mark E. Kleinman, Kiyoshi Yamada, Atsunobu Takeda, Vasu Chandrasekaran, Miho Nozaki, Judit Z. Baffi, Romulo J. C. Albuquerque, Satoshi Yamasaki, Masahiro Itaya, Yuzhen Pan, Binoy Appukuttan, Daniel Gibbs, Zhenglin Yang, Katalin Karikó, Balamurali K. Ambati, Traci A. Wilgus, Luisa A. DiPietro, Eiji Sakurai, Kang Zhang, Justine R. Smith, Ethan W. Taylor & Jayakrishna Ambati
doi:10.1038/nature06765
Abstract | Full Text | PDF (824K) | Supplementary information
Insight
Imaging in the era of molecular oncology
Ralph Weissleder & Mikael J. Pittet
doi:10.1038/nature06917
Article
Following translation by single ribosomes one codon at a time
Jin-Der Wen, Laura Lancaster, Courtney Hodges, Ana-Carolina Zeri, Shige H. Yoshimura, Harry F. Noller, Carlos Bustamante & Ignacio Tinoco
doi:10.1038/nature06716
Abstract | Full Text | PDF (397K) | Supplementary information
Insight
Translating insights from the cancer genome into clinical practice
Lynda Chin & Joe W. Gray
doi:10.1038/nature06914
Commentary
Dangerous assumptions
Roger Pielke, Jr, Tom Wigley & Christopher Green
doi:10.1038/452531a
Insight
Enabling personalized cancer medicine through analysis of gene-expression patterns
Laura J. van 't Veer & René Bernards
doi:10.1038/nature06915
News and Views
RNA interference: Generic block on angiogenesis
Raghu Kalluri & Keizo Kanasaki
doi:10.1038/452543a