Editor-in-Chief: John W Griffin, MD

Nature Clinical Practice Neurology delivers timely interpretations of key research developments, translating the latest findings into clinical practice. Our Editor-in-Chief and international Advisory Board ensure comprehensive coverage of topical issues throughout the year, with the highest standards of editorial quality and integrity that are hallmarks of Nature Publishing Group.

Table of Contents: November 2008

Free featured article

A case of cocaine-induced basilar artery thrombosis

Clare MacEwen, Mike Ward and Alastair Buchan

This article discusses the case of a 40-year-old man with basilar artery thrombosis, which, after numerous investigations, was found to be attributable to cocaine use. The authors highlight the importance of asking patients about cocaine exposure as part of a routine cardiovascular history, and they provide the first description of the use of thrombolysis to treat cocaine-induced stroke.

Free featured article

Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis

Claire Henchcliffe and M Flint Beal

Mitochondrial dysfunction and oxidative stress have been strongly implicated in the pathogenesis of Parkinson disease (PD), and the products of several PD-associated genes become localized to the mitochondria under certain conditions. In this article, Henchcliffe and Beal review recent developments in mitochondrial biology that have contributed to our understanding of the disease process in PD, and they discuss how this knowledge might aid in the development of 'mitochondrial therapies' for PD.

Nature Insights Neuropsychiatric disorders

Nature Insight Neuropsychiatric disorders

This Insight highlights recent progress made in our understanding of the molecular and cellular biology, genetics, and neural circuitry underlying neuropsychiatric diseases. Together, this research points to promising integrative approaches for tackling neuropsychiatric research in the post-genomic era, and strategies for developing future therapies.

Access the Insight free online for six months
Produced with an educational grant provided by Eli Lilly & Company

Training Matters

The new pain curriculum: a guide for neurologists who teach

Beth Murinson and Jason Rosenberg

Pain is a leading reason for seeking medical care, but the management of pain is often felt to be inadequate. A good place to start tackling this problem is in the training of future doctors. This Training Matters article provides excellent advice for neurologists who are involved in the teaching of pain and its management.