Nature Clinical Practice Rheumatology Nature Clinical Practice Rheumatology provides physicians with authoritative and timely interpretations of key developments in the field, translating the latest findings into clinical practice. http://www.nature.com/ncprheum/current_issue/ Nature Publishing Group en © Nature Publishing Group Nature Clinical Practice Rheumatology 1745-8382 1745-8390 © Nature Publishing Group permissions@nature.com Nature Clinical Practice Rheumatology http://www.nature.com/includes/rj_globnavimages/ncprheum_logo.gif http://www.nature.com/ncprheum/ Screening for osteoporosis in men: comment on the American College of Physicians clinical guidelines http://dx.doi.org/10.1038/ncprheum0923 Screening for osteoporosis in men: comment on the American College of Physicians clinical guidelines

Nature Clinical Practice Rheumatology. doi:10.1038/ncprheum0923

Authors: Marc C Hochberg & Robert A Adler

]]> Screening for osteoporosis in men: comment on the American College of Physicians clinical guidelines Marc C Hochberg Robert A Adler doi:10.1038/ncprheum0923 Nature Clinical Practice Rheumatology 2008-10-07 Nature Clinical Practice Rheumatology 2008-10-07 Guidelines Summary Etanercept for patients with RA: more is not always better http://dx.doi.org/10.1038/ncprheum0936 Etanercept for patients with RA: more is not always better

Nature Clinical Practice Rheumatology. doi:10.1038/ncprheum0936

Author: Joel M Kremer

]]> Etanercept for patients with RA: more is not always better Joel M Kremer doi:10.1038/ncprheum0936 Nature Clinical Practice Rheumatology 2008-10-28 Nature Clinical Practice Rheumatology 2008-10-28 Practice Point Is long-term etanercept therapy safe and effective in patients with juvenile RA? http://dx.doi.org/10.1038/ncprheum0925 Is long-term etanercept therapy safe and effective in patients with juvenile RA?

Nature Clinical Practice Rheumatology. doi:10.1038/ncprheum0925

Author: Raphael Hirsch

]]> Is long-term etanercept therapy safe and effective in patients with juvenile RA? Raphael Hirsch doi:10.1038/ncprheum0925 Nature Clinical Practice Rheumatology 2008-10-14 Nature Clinical Practice Rheumatology 2008-10-14 Practice Point Do wedged insoles improve outcomes in patients with knee osteoarthritis? http://dx.doi.org/10.1038/ncprheum0926 Do wedged insoles improve outcomes in patients with knee osteoarthritis?

Nature Clinical Practice Rheumatology. doi:10.1038/ncprheum0926

Author: Jeffrey N Katz

]]> Do wedged insoles improve outcomes in patients with knee osteoarthritis? Jeffrey N Katz doi:10.1038/ncprheum0926 Nature Clinical Practice Rheumatology 2008-10-14 Nature Clinical Practice Rheumatology 2008-10-14 Practice Point First pregabalin and now duloxetine for fibromyalgia syndrome: closer to a brave new world? http://dx.doi.org/10.1038/ncprheum0938 First pregabalin and now duloxetine for fibromyalgia syndrome: closer to a brave new world?

Nature Clinical Practice Rheumatology. doi:10.1038/ncprheum0938

Author: Chad S Boomershine

]]> First pregabalin and now duloxetine for fibromyalgia syndrome: closer to a brave new world? Chad S Boomershine doi:10.1038/ncprheum0938 Nature Clinical Practice Rheumatology 2008-11-04 Nature Clinical Practice Rheumatology 2008-11-04 Clinical Advance Are patients with RA at increased risk of malignancy? http://dx.doi.org/10.1038/ncprheum0924 Are patients with RA at increased risk of malignancy?

Nature Clinical Practice Rheumatology. doi:10.1038/ncprheum0924

Author: Kimme L Hyrich

]]> Are patients with RA at increased risk of malignancy? Kimme L Hyrich doi:10.1038/ncprheum0924 Nature Clinical Practice Rheumatology 2008-10-14 Nature Clinical Practice Rheumatology 2008-10-14 Clinical Advance Denosumab—a novel strategy to prevent structural joint damage in patients with RA? http://dx.doi.org/10.1038/ncprheum0927 Denosumab—a novel strategy to prevent structural joint damage in patients with RA?

Nature Clinical Practice Rheumatology. doi:10.1038/ncprheum0927

Authors: Georg Schett & Jean-Pierre David

]]> Denosumab—a novel strategy to prevent structural joint damage in patients with RA? Georg Schett Jean-Pierre David doi:10.1038/ncprheum0927 Nature Clinical Practice Rheumatology 2008-10-07 Nature Clinical Practice Rheumatology 2008-10-07 Clinical Advance The importance of recognizing scleroderma-type disorders in clinical practice http://dx.doi.org/10.1038/ncprheum0937 Scleroderma-like disorders, which often have marked clinical overlap with scleroderma, can present a diagnostic challenge. In this Viewpoint, the author describes key clinical and laboratory features that can aid early diagnosis and prompt appropriate management. The importance of recognizing scleroderma-type disorders in clinical practice

Nature Clinical Practice Rheumatology. doi:10.1038/ncprheum0937

Author: Laura K Hummers

]]> The importance of recognizing scleroderma-type disorders in clinical practice Laura K Hummers doi:10.1038/ncprheum0937 Nature Clinical Practice Rheumatology 2008-10-28 Nature Clinical Practice Rheumatology 2008-10-28 Viewpoint Common mistakes in the clinical use of bone mineral density testing http://dx.doi.org/10.1038/ncprheum0928 Bone mineral density testing is used to diagnose osteoporosis, assess the associated fracture risk and monitor changes over time. In this Review, the authors describe the common technical and interpretation errors that are encountered in the clinical use of bone densitometry, with a primary focus on DXA. Common mistakes in the clinical use of bone mineral density testing

Nature Clinical Practice Rheumatology. doi:10.1038/ncprheum0928

Authors: E Michael Lewiecki & Nancy E Lane

]]> Common mistakes in the clinical use of bone mineral density testing E Michael Lewiecki Nancy E Lane doi:10.1038/ncprheum0928 Nature Clinical Practice Rheumatology 2008-10-21 Nature Clinical Practice Rheumatology 2008-10-21 Review Painful knee locking caused by gouty tophi successfully treated with allopurinol http://dx.doi.org/10.1038/ncprheum0945 Although arthroscopic removal is the usual treatment for intra-articular tophi, surgery is not always an option. This Case Study demonstrates that continuous urate-lowering therapy is a suitable alternative: in a 67-year-old man, painful locking of the knee secondary to intra-articular tophi was alleviated following continuous allopurinol therapy. Resolution of the tophi was demonstrated by CT. Painful knee locking caused by gouty tophi successfully treated with allopurinol

Nature Clinical Practice Rheumatology. doi:10.1038/ncprheum0945

Authors: Soumya Chatterjee & Hakan Ilaslan

]]> Painful knee locking caused by gouty tophi successfully treated with allopurinol Soumya Chatterjee Hakan Ilaslan doi:10.1038/ncprheum0945 Nature Clinical Practice Rheumatology 2008-11-11 Nature Clinical Practice Rheumatology 2008-11-11 Case Study