Nature Neuroscience 8, 1635 - 1636 (2005)
doi:10.1038/nn1205-1635
Tinker to Evers to Chance: semaphorin signaling takes teamworkPaul A Garrity
Paul A. Garrity is in the Department of Biology, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, Massachusetts 02139-4307, USA. pgarrity@mit.edu
The Rho-family GTPases act downstream of axon guidance receptors, controlling proteins that remodel the cytoskeleton. New work now suggests that these GTPases also team up to regulate activation of the semaphorin-3A receptor itself.
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