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| Food intake and body weight are subject to complex regulation by the hypothalamus and other brain centers. This focus presents six commissioned articles highlighting current progress in the neurobiology of feeding regulation, energy metabolism and obesity. It is sponsored by the Obesity Research Task Force of the National Institutes of Health, and freely accessible through July 2005. |
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| Editorial | Top |
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The perils of public debate p535
doi:10.1038/nn0505-535
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(72K)
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| Correspondence | Top |
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Is prefrontal white matter enlargement a human evolutionary specialization? pp537 - 538
Chet C Sherwood, Ralph L Holloway, Katerina Semendeferi
& Patrick R Hof
doi:10.1038/nn0505-537
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(105K)
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Reply to "Is prefrontal white matter enlargement a human evolutionary specialization?" p538
P Thomas Schoenemann, L Daniel Glotzer
& Michael J Sheehan
doi:10.1038/nn0505-538
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(60K)
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| Book Review | Top |
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Understanding brain evolution p539
Reviewed by: Jon H Kaas
doi:10.1038/nn0505-539
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(130K)
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| News and Views | Top |
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Imaging orientation selectivity: decoding conscious perception in V1 pp541 - 542
Geoffrey M Boynton
doi:10.1038/nn0505-541
Abstract | Full text | PDF
(174K)
See also: Article by Kamitani & Tong | Article by Haynes & Rees |
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Finding the G spot on fusion machinery pp542 - 544
Jane Sullivan
doi:10.1038/nn0505-542
Abstract | Full text | PDF
(136K)
See also: Article by Gerachshenko et al. |
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Axon formation: fate versus growth pp544 - 546
Hui Jiang
& Yi Rao
doi:10.1038/nn0505-544
Abstract | Full text | PDF
(291K)
See also: Article by Da Silva et al. |
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Song learning and sleep pp546 - 548
Daniel Margoliash
doi:10.1038/nn0505-546
Abstract | Full text | PDF
(157K)
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Trafficking in emotions pp548 - 550
Dan Ehninger, Anna Matynia
& Alcino J Silva
doi:10.1038/nn0505-548
Abstract | Full text | PDF
(251K)
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SK channels: a new twist to synaptic plasticity p550
Kalyani Narasimhan
doi:10.1038/nn0505-550
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(171K)
See also: Article by Ngo-Anh et al. | Article by Faber et al. |
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| Introduction | Top |
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Focus on Feeding Regulation and Obesity
Neurobiology of obesity p551
Annette Markus
doi:10.1038/nn0505-551
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(73K)
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| Sponsor's Foreword | Top |
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Focus on Feeding Regulation and Obesity
Obesity on the brain pp552 - 553
Allen Spiegel, Elizabeth Nabel, Nora Volkow, Story Landis
& Ting-Kai Li
doi:10.1038/nn0505-552
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(91K)
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| Commentary | Top |
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Focus on Feeding Regulation and Obesity
How can drug addiction help us understand obesity? pp555 - 560
Nora D Volkow
& Roy A Wise
Published online: 26 April 2005 | doi:10.1038/nn1452
Abstract | Full text | PDF
(564K)
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| Perspective | Top |
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Focus on Feeding Regulation and Obesity
The hardship of obesity: a soft-wired hypothalamus pp561 - 565
Tamas L Horvath
Published online: 06 April 2005 | doi:10.1038/nn1453
Abstract | Full text | PDF
(439K)
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| Reviews | Top |
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Focus on Feeding Regulation and Obesity
Molecular and anatomical determinants of central leptin resistance pp566 - 570
Heike Münzberg
& Martin G Myers Jr
Published online: 26 April 2005 | doi:10.1038/nn1454
Abstract | Full text | PDF
(161K)
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Focus on Feeding Regulation and Obesity
Anatomy and regulation of the central melanocortin system pp571 - 578
Roger D Cone
Published online: 26 April 2005 | doi:10.1038/nn1455
Abstract | Full text | PDF
(312K)
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Focus on Feeding Regulation and Obesity
Hypothalamic sensing of fatty acids pp579 - 584
Tony K T Lam, Gary J Schwartz
& Luciano Rossetti
Published online: 26 April 2005 | doi:10.1038/nn1456
Abstract | Full text | PDF
(795K)
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Focus on Feeding Regulation and Obesity
Endocannabinoid control of food intake and energy balance pp585 - 589
Vincenzo Di Marzo
& Isabel Matias
Published online: 26 April 2005 | doi:10.1038/nn1457
Abstract | Full text | PDF
(193K)
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| Brief Communications | Top |
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Neurons in macaque area V4 acquire directional tuning after adaptation to motion stimuli pp591 - 593
Andreas S Tolias, Georgios A Keliris, Stelios M Smirnakis
& Nikos K Logothetis
Published online: 17 April 2005 | doi:10.1038/nn1446
Abstract | Full text | PDF
(138K)
| Supplementary Information |
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Midbrain dopamine and prefrontal function in humans: interaction and modulation by COMT genotype pp594 - 596
Andreas Meyer-Lindenberg, Philip D Kohn, Bhaskar Kolachana, Shane Kippenhan, Aideen McInerney-Leo, Robert Nussbaum, Daniel R Weinberger
& Karen Faith Berman
Published online: 10 April 2005 | doi:10.1038/nn1438
Abstract | Full text | PDF
(233K)
| Supplementary Information |
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| Articles | Top |
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G  acts at the C terminus of SNAP-25 to mediate presynaptic inhibition pp597 - 605
Tatyana Gerachshenko, Trillium Blackmer, Eun-Ja Yoon, Cheryl Bartleson, Heidi E Hamm
& Simon Alford
Published online: 17 April 2005 | doi:10.1038/nn1439
Abstract | Full text | PDF
(520K)
| Supplementary Information
See also: News and Views by Sullivan |
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Asymmetric membrane ganglioside sialidase activity specifies axonal fate pp606 - 615
Jorge Santos Da Silva, Takafumi Hasegawa, Taeko Miyagi, Carlos G Dotti
& Jose Abad-Rodriguez
Published online: 17 April 2005 | doi:10.1038/nn1442
Abstract | Full text | PDF
(580K)
| Supplementary Information
See also: News and Views by Jiang & Rao |
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A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis pp616 - 625
Fei He, Weihong Ge, Keri Martinowich, Sara Becker-Catania, Volkan Coskun, Wenyu Zhu, Hao Wu, Diogo Castro, Francois Guillemot, Guoping Fan, Jean de Vellis
& Yi E Sun
Published online: 24 April 2005 | doi:10.1038/nn1440
Abstract | Full text | PDF
(539K)
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PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain pp626 - 634
Tibor Rohács, Coeli M B Lopes, Ioannis Michailidis
& Diomedes E Logothetis
Published online: 24 April 2005 | doi:10.1038/nn1451
Abstract | Full text | PDF
(465K)
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SK channels regulate excitatory synaptic transmission and plasticity in the lateral amygdala pp635 - 641
E S Louise Faber, Andrew J Delaney
& Pankaj Sah
Published online: 24 April 2005 | doi:10.1038/nn1450
Abstract | Full text | PDF
(574K)
See also: News and Views by Narasimhan |
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SK channels and NMDA receptors form a Ca2+-mediated feedback loop in dendritic spines pp642 - 649
Thu Jennifer Ngo-Anh, Brenda L Bloodgood, Michael Lin, Bernardo L Sabatini, James Maylie
& John P Adelman
Published online: 24 April 2005 | doi:10.1038/nn1449
Abstract | Full text | PDF
(500K)
See also: News and Views by Narasimhan |
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Fast delayed rectifier potassium current is required for circadian neural activity pp650 - 656
Jason N Itri, Stephan Michel, Mariska J Vansteensel, Johanna H Meijer
& Christopher S Colwell
Published online: 24 April 2005 | doi:10.1038/nn1448
Abstract | Full text | PDF
(364K)
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 -Synuclein phosphorylation controls neurotoxicity and inclusion formation in a Drosophila model of Parkinson disease pp657 - 663
Li Chen
& Mel B Feany
Published online: 17 April 2005 | doi:10.1038/nn1443
Abstract | Full text | PDF
(430K)
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The MAPK pathway and Egr-1 mediate stress-related behavioral effects of glucocorticoids pp664 - 672
Jean-Michel Revest, Francesco Di Blasi, Pierre Kitchener, Françoise Rougé-Pont, Aline Desmedt, Marc Turiault, François Tronche
& Pier Vincenzo Piazza
Published online: 17 April 2005 | doi:10.1038/nn1441
Abstract | Full text | PDF
(472K)
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Electroreceptor neuron dynamics shape information transmission pp673 - 678
Maurice J Chacron, Leonard Maler
& Joseph Bastian
Published online: 03 April 2005 | doi:10.1038/nn1433
Abstract | Full text | PDF
(271K)
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Decoding the visual and subjective contents of the human brain pp679 - 685
Yukiyasu Kamitani
& Frank Tong
Published online: 24 April 2005 | doi:10.1038/nn1444
Abstract | Full text | PDF
(474K)
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See also: News and Views by Boynton |
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Predicting the orientation of invisible stimuli from activity in human primary visual cortex pp686 - 691
John-Dylan Haynes
& Geraint Rees
Published online: 24 April 2005 | doi:10.1038/nn1445
Abstract | Full text | PDF
(401K)
| Supplementary Information
See also: News and Views by Boynton |
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