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Published online 26 July 2007 | Nature | doi:10.1038/news070723-10

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Single gene deletion boosts lifespan

Mutant mice live longer, age slower and eat more.

Researchers have created a mutant mouse that lives longer despite eating more and weighing less — all thanks to the loss of a single protein.

Without this protein, the body is less susceptible to the heart-pounding effects of the hormone adrenaline, and may become more resistant to some forms of stress.

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