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Published online 5 December 2007 | Nature 450, 775 (2007) | doi:10.1038/450775a
News in Brief
Safer way to make human stem-like cells revealed
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Please note this is News in Brief, and so will be a short article.
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Removing a carcinogenic gene will not remove the deceptive nature of iPS cells Shi V. Liu (SVL@logibio.com) In my previous communications to Yamanaka I have pointed out to him that his so-called ‘induced’ pluripotent stem (iPS) cells may well be the pre-existing stem cells that were somehow activated and/or enhanced in their reproduction. C-Myc as a carcinogenic gene might play a role in this activation/enhancement but may not be essential since the so-called ‘induction’ of new stem cells is in fact a selection/proliferation of the pre-existing stem cells which can be facilitated by the introduction of some ‘stemness’ markers. The so-called ‘reprogramming’ an adult normal (differentiated) skin cell back to an embryonic stem cell (ES)-like cell is a hoax. The ‘indistinguishable’ claim made for iPS cells against ES cells is just a self-cheating. For more information please read many publications (some were rejected by the ‘top’ journals) in the following links: Stem cells (http://im1.biz/StemCell.htm or http://im1.biz/StemCell.pdf) Cloning (http://im1.biz/Cloning.htm or http://im1.biz/Cloning.pdf) Aging (http://im1.biz/Aging.htm or http://im1.biz/Aging.pdf)