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Published online 6 August 2008 | Nature 454, 674 (2008) | doi:10.1038/454674a
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Genetic fact-check for ageing story
Study probes geriatric gene pool.
A genetic study of healthy elderly people aims to uncover the secret of living to a ripe old age — intact.
The 'Wellderly Study' is a joint initiative between the Scripps Research Institute in La Jolla, California, and scientists at the J.
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It seems a very nice idea for study of identifying longivity basis. I would like to mention here that whole genome sequencing for the 2000 genomes is a big task and take a longer duration. As there is basic differences among humans is SNPs and CNVs, why not concentrate on that first. I think that the same kind of conclusion can be drawn. At last a great initiative... Thanks.
The people above 80 years from the diverse populations could be taken for the genotyping, and the differences vs. similarity analysis will contribute to understanding of possible genes and their role to longivity as well as to prioritize genes for sequencing.
It a nice research the world awaits to conclude. I wonder, if in a large enough group of 2000 study units, the research team have couple(s) with off spring: inherited the targeted genes of health and longevity, should be included in the study. The offspring must be able to perform too with these genes…