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Published online 10 September 2008 | Nature 455, 160-164 (2008) | doi:10.1038/455160a
Corrected online: 3 October 2008

News Feature

Protein engineering: The fate of fingers

Proteins with 'zinc fingers' designed to bind almost any DNA sequence will soon be available to any lab that wants them — from two very different sources. Helen Pearson reports on a revolution in designer biology.

"There is only one word that matters in biology," says pioneering molecular biologist Aaron Klug, "and that is specificity. The truth is in the details, not the broad sweeps.

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