• 1600 BC
    • Indian texts describe fever with malaria-like symptoms.
    • 95 BC
    • Lucretius suggests that a micro-organism might cause 'swamp fever'
    • 450 AC
    • Oldest known source of malarial DNA.
    • c. 1640
    • Spanish colonists in South America discover quinine. The natives probably knew about it before then.
    • 1716
    • Giovanni Maria Lancisi, a Roman doctor, notes that draining swamps curbs malaria. He suggests mosquitoes spread the disease, but few listen.
    • 1880
    • French army surgeon Charles Louis Alfonse Laveran spots malaria parasite in blood.
    • 1897
    • British doctor Ronald Ross observes malaria parasite in mosquitoes.
    • 1934
    • Chloroquine discovered in Germany. Forgotten and rediscovered in 1940s.
    • 1939
    • DDT developed
    • 1939-45
    • Second World War: the risk to soldiers prompts probably the most intense malaria research effort ever. Several new drugs discovered as a result.
    • 1956
    • WHO launches global campaign to eradicate malaria.
    • 1960s
    • Drug-resistant parasites and DDT-resistant mosquitoes become widespread.
    • 1967
    • WHO abandons malaria eradication in favour of control.
    • 1979
    • Chinese researchers describe artemisinins, a new class of malaria drug derrived from the sweet wormwood plant.
    • 1983
    • First Plasmodium gene cloned. Mutation leading to drug resistance found.
    • 1999
    • PATH malaria vaccine initiative founded on a $50 million grant from the Gates Foundation.
    • 2003
    • 2,000 children in Africa are given an experimental vaccine, RTS,S, to see how it fares in protecting against malaria.
    • 2006
    • Artemisinin is synthesized in the lab for the first time, raising the prospect of cheaper, more adaptable drugs.
    • 2006
    • The World Health Organisation launches an International Medical Products Anti-Counterfeiting Taskforce (IMPACT), in large part to beat back the tide of fake malarial drugs in Asia.
    • 2007
    • The Bill & Melinda Gates foundation calls to eradicate malaria.
  •  

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