An expanded role for wild-type huntingtin in neuronal transcription
Leslie Michels Thompson
The author is in the Department of Psychiatry and Human Behavior, Department of Biological Chemistry, University of California Irvine, Irvine, California 92697-4260, USA. lmthomps@uci.edu
Huntington disease is caused by a polyglutamine repeat expansion in the huntingtin protein. A new study highlights an important role for the normal protein in neuronal transcriptional regulation.
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