1
Laurence Hurst is in the Department of Biology and Biochemistry, University of Bath, UK. l.d.hurst@bath.ac.uk
2
Csaba Pál is at MTA, Theoretical Biology Research Group, Eotvos Lorand University, Budapest, Hungary
Like most organisms, yeast has relatively few genes that are necessary for viability. The presence of a duplicate gene elsewhere in the genome underpins many cases of dispensability. A new study suggests that the backup mechanism is more complex than previously assumed and requires feedback loops that ensure transcriptional upregulation of the duplicate.
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