Focuses and supplements
Nature Immunology provides reviews and commentary illuminating topics of particular interest.
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2008
Leukocyte Trafficking
Immune cells are constantly in motion in surveillance for potential microbial threats. Here we present a collection of reviews that describe the trafficking patterns, cues and means by which immune cells transit tissues in health and in response to infections.
Nov Vol. 9, No. 9
Natural Killer Cells
An overview, two review articles, two perspective articles and one personal essay discuss the differentiation, responsiveness and biological functions of natural killer cells.
Nov Vol. 9, No. 5
2007
Pathogenesis
A comprehensive overview of pathogenesis: seven specially commissioned articles discuss host-pathogen encounters from several angles, with special emphasis on immune outcomes.
Nov Vol. 8, No. 11
Signaling in the Type I Interferon Antiviral Innate Immune Response
Virus infection triggers a type I interferon response. This poster provides an overview of the networks and components of the antiviral-induced IFN signaling pathways. The poster is available thanks to support from
Sep Vol. 8, No. 9
Lymphocyte Lineage Specification Factors
An overview, three review articles and two personal essays discuss the identification and function of transcription factors that regulate the differentiation of lymphocyte lineages.
May Vol. 8, No. 5
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2006
Non-Toll-like Innate Immune Proteins -
A comprehensive overview and four review articles discuss the functions of plant and animal innate immune system receptors in the context of pathogen recognition and other immune functions.
December Vol. 7, No. 12
Specialized Immunological Niches -
Five especially commissioned articles that discuss how immune cells communicate in selected tissue microenvironments.
April Vol. 7, No. 4
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2005
Dampening Inflammation -
A comprehensive overview, and three review articles examine how inflammation is dampened by the immune system.
December Vol. 6, No. 12
Nature Immunology turns five -
To celebrate our 5 years of serving the immunology community, we have assembled a collection of papers that illustrates the breadth of subject matter our pages cover.
July Vol. 6, No. 7
Regulatory T Cells -
Four review articles and a perspective examine the biology and function of regulatory T cells.
April Vol. 6, No. 4
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2004
Bridging Innate and Adaptive Immunity -
A comprehensive overview, three review articles and a perspective examine how the innate immunity influences the outcome of the adaptive immune response.
October Vol. 5, No. 10
Making Peptides for Presentation -
Immune surveillance requires constant sampling of cellular peptides by T cells. Here, we present four reviews describing the generation of antigenic peptide epitopes and the cellular enzymes responsible.
July Vol. 5, No. 7
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2003
Chromatin Dynamics -
A comprehensive overview and four review articles that demystify the molecular mechanisms underlying lymphocytes' unique recombination events and specific gene expression programs.
July Vol. 4, No. 7
Cell Death and Immunity -
This joint web focus with Nature Reviews Immunology examines recent inroads into how cell death pathways intersect with the immune system during both development and disease.
May Vol. 4, No. 5
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2002
Immune Evasion -
A series of comprehensive reviews examining mechanisms of immune escape. The juxtaposition of tumor with microbial immune evasion reveals the many parallels between the different systems.
November Vol. 3, No. 11
Hematopoietic Stem Cells -
The hematopoietic stem cells that reside in our bone marrow might aptly be described as our source of vitality. This focus contains an analysis of progress and news in hematopoietic stem cell research.
April Vol. 3, No. 4
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2001
Autoimmunity -
The mechanisms that cause autoimmune disorders are not fully worked out, in spite of intense effort. This focus thoroughly examines recent clinical and research progress in understanding autoimmunity.
September Vol. 2, No. 9
Chemokines -
Chemokines orchestrate the migration of cells that bear appropriate receptors. Here Nature Immunology chronicles progress in chemokine research, an area that has exploded in the last 10 years.
February Vol. 2, No. 2