Therapeutic applications for hematopoietic stem cell gene transfer
Claudio Bordignon
& Maria Grazia Roncarolo
HSR−Telethon Institute for Gene Therapy (TIGET) of Genetic Disease, Cancer Immunotherapy and Gene Therapy Program, Istituto Scientifico H.S. Raffaele, Universitá Vita-Salute San Raffaele, via Olgettina 58, 20132 Milan, Italy. claudio.bordignon@hsr.it
Transfer of genes into HSCs could be used to treat a variety of diseases from AIDS to cancer. Here Bordignon and Roncarolo discuss the logistics and progress of HSC gene transfer technology for the treatment of different diseases.