Masaru Taniguchi, Ken-ichiro Seino & Toshinori Nakayama are in the Laboratory for Immunoregulation, RIKEN Research Center for Allergy and Immunology, Tsurumi, Yokohama and Department of Molecular Immunology, Graduate School of Medicine, Chiba University, Chiba, Japan. taniguti@med.m.chiba-u.ac.jp
Although natural killer T cells are activated during infection, it is not clear how this process occurs. Closer examination indicates that recognition of endogenous ligands and interleukin 12, rather than bacterial products, may drive the activation process.
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–producing NKT response induced with 
-galactosylceramide–loaded DCs
